Search Results - "Bornscheuer, Uwe"
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Biocatalysis: Enzymatic Synthesis for Industrial Applications
Published in Angewandte Chemie International Edition (04-01-2021)“…Biocatalysis has found numerous applications in various fields as an alternative to chemical catalysis. The use of enzymes in organic synthesis, especially to…”
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The fourth wave of biocatalysis is approaching
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (13-01-2018)“…Biocatalysis has undergone a tremendous development in the past few years. A plethora of methods enable the rather rapid tailored-design of an enzyme for a…”
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Feeding on plastic
Published in Science (American Association for the Advancement of Science) (11-03-2016)“…A bacterium completely degrades poly(ethylene terephthalate) [Also see Report by Yoshida et al. ] An estimated 311 million tons of plastics are produced…”
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Directed Evolution Empowered Redesign of Natural Proteins for the Sustainable Production of Chemicals and Pharmaceuticals
Published in Angewandte Chemie International Edition (02-01-2019)“…Directed evolution has advanced into a standard industrial “tool” to tailor naturally occurring proteins for a variety of biotechnological applications, thus…”
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Recent advances in (chemo)enzymatic cascades for upgrading bio-based resources
Published in Chemical communications (Cambridge, England) (14-10-2021)“…Developing (chemo)enzymatic cascades is very attractive for green synthesis, because they streamline multistep synthetic processes. In this Feature Article, we…”
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Concluding remarks: biocatalysis
Published in Faraday discussions (11-09-2024)“…Biocatalysis is a rapidly evolving field with increasing impact in organic synthesis, chemical manufacturing and medicine. The reflected the current state of…”
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Hot spots for the protein engineering of Baeyer-Villiger monooxygenases
Published in Biotechnology advances (01-01-2018)“…Baeyer-Villiger monooxygenases (BVMOs) are versatile biocatalysts for the conversion of ketones to lactones or esters while also being able to efficiently…”
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Marine Polysaccharides: Occurrence, Enzymatic Degradation and Utilization
Published in Chembiochem : a European journal of chemical biology (01-07-2021)“…Macroalgae species are fast growing and their polysaccharides are already used as food ingredient due to their properties as hydrocolloids or they have…”
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Systematic Analysis of the MIO‐forming Residues of Aromatic Ammonia Lyases
Published in Chembiochem : a European journal of chemical biology (15-03-2024)“…Aromatic ammonia lyases (AALs) and tyrosine/phenylalanine ammonia mutases (TAM/PAM) are 3,5‐dihydro‐5‐methylidene‐4H‐imidazol‐4‐one (MIO)‐dependent enzymes…”
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Enzymes in Lipid Modification
Published in Annual review of food science and technology (25-03-2018)“…This article reviews the application of enzymes in lipid modification. Lipases are the most established biocatalysts used for the synthesis of structured…”
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Biocatalysis: Successfully Crossing Boundaries
Published in Angewandte Chemie International Edition (24-03-2016)“…“ … The creation of robust biocatalysts with desired properties was previously challenging. Nowadays, knowledge of bioinformatics, protein engineering,…”
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Recent trends in biocatalysis
Published in Chemical Society reviews (21-07-2021)“…Biocatalysis has undergone revolutionary progress in the past century. Benefited by the integration of multidisciplinary technologies, natural enzymatic…”
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Cascade catalysis--strategies and challenges en route to preparative synthetic biology
Published in Chemical communications (Cambridge, England) (07-04-2015)“…Nature's smartness and efficient assembling cascade type reactions inspired biologists and chemists all around the world. Tremendous effort has been directed…”
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Cascades of Evolved Enzymes for the Synthesis of Complex Molecules
Published in Angewandte Chemie International Edition (26-09-2022)“…Thanks to advances in enzyme discovery and protein engineering combined with the development of enzymatic multistep reaction cascades, new efficient routes for…”
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Thermophilic whole‐cell degradation of polyethylene terephthalate using engineered Clostridium thermocellum
Published in Microbial biotechnology (01-03-2021)“…Summary Polyethylene terephthalate (PET) is a mass‐produced synthetic polyester contributing remarkably to the accumulation of solid plastics waste and…”
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Fatty Acids and their Derivatives as Renewable Platform Molecules for the Chemical Industry
Published in Angewandte Chemie International Edition (06-09-2021)“…Oils and fats of vegetable and animal origin remain an important renewable feedstock for the chemical industry. Their industrial use has increased during the…”
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Chemical biology: A radical change in enzyme catalysis
Published in Nature (London) (15-12-2016)Get full text
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Biocatalytic Routes to Optically Active Amines
Published in ChemCatChem (24-08-2009)“…Optically active amines and amino acids play an important role in the pharmaceutical, agrochemical, and chemical industries. They are frequently used as…”
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Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
Published in Nature communications (12-04-2019)“…The extreme durability of polyethylene terephthalate (PET) debris has rendered it a long-term environmental burden. At the same time, current recycling efforts…”
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Efficient Enzymatic Synthesis of Carbamates in Water Using Promiscuous Esterases/Acyltransferases
Published in Angewandte Chemie International Edition (22-07-2024)“…Biocatalysis provides an attractive approach to facilitate synthetic reactions in aqueous media. Motivated by the discovery of promiscuous aminolysis activity…”
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