Search Results - "Bornkamp, Nicole"
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Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways
Published in Nature immunology (01-07-2019)“…The molecular and cellular processes that lead to renal damage and to the heterogeneity of lupus nephritis (LN) are not well understood. We applied single-cell…”
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Discontinuation of hydroxychloroquine in older patients with systemic lupus erythematosus: a multicenter retrospective study
Published in Arthritis research & therapy (17-08-2020)“…Abstract Background Although hydroxychloroquine (HCQ) is a mainstay of treatment for patients with systemic lupus erythematosus (SLE), ocular toxicity can…”
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When a birth cohort grows up: challenges and opportunities in longitudinal developmental origins of health and disease (DOHaD) research
Published in Journal of developmental origins of health and disease (01-04-2023)“…High-quality evidence from prospective longitudinal studies in humans is essential to testing hypotheses related to the developmental origins of health and…”
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Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis
Published in JCI insight (04-05-2017)Get full text
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CS-31 Safety of hydroxychloroquine withdrawal in older adults with systemic lupus erythematosus
Published in Lupus science & medicine (01-08-2018)“…BackgroundAlthough hydroxychloroquine (HCQ) is a mainstay of treatment for patients with Systemic Lupus Erythematosus (SLE), ocular toxicity can result from…”
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Abstract MP35: Hair Cortisol Concentrations Are Associated With Greater Adiposity in Mid-Adolescence
Published in Circulation (New York, N.Y.) (28-02-2023)“…IntroductionHair cortisol concentration (HCC) is a biomarker of long-term stress. Higher HCC is associated with body mass index (BMI) and other adiposity…”
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Abstract P320: Adverse Childhood Experiences Are Associated With Greater Adiposity in Midlife Women: Findings From the Prospective Project Viva Cohort
Published in Circulation (New York, N.Y.) (28-02-2023)“…IntroductionThe associations of adverse childhood experiences (ACEs) with adiposity are not well characterized in midlife women, a life stage when…”
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Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis
Published in JCI insight (04-05-2017)“…Lupus nephritis is a leading cause of mortality among systemic lupus erythematosus (SLE) patients, and its heterogeneous nature poses a significant challenge…”
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Human low‐affinity IgG receptor FcγRIIA polymorphism H131R associates with subclinical atherosclerosis and increased platelet activity in systemic lupus erythematosus
Published in Journal of thrombosis and haemostasis (01-03-2019)“…Essentials Systemic lupus erythematosus (SLE) patients are at increased risk for premature CVD. Platelet activity, vascular dysfunction and carotid artery…”
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Association of Autoantibody Concentrations and Trajectories With Lupus Nephritis Histologic Features and Treatment Response
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2024)“…Objective Autoantibodies are a hallmark of lupus nephritis (LN), but their association with LN classes and treatment response are not adequately known. In this…”
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Hair cortisol concentrations are associated with greater adiposity in late adolescence amongst non‐Hispanic White individuals
Published in Pediatric obesity (01-12-2024)“…Summary Introduction Hair cortisol concentration (HCC) is a biomarker of long‐term stress. Higher HCC is associated with higher adiposity in adults; however,…”
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Single-cell RNA sequencing of skin and kidney cells in lupus nephritis provides insights into pathogenesis and indicates novel potential biomarkers
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract Classification and treatment decisions in lupus nephritis (LN) are largely based on renal histology. Single-cell RNAseq (scRNAseq) analysis may…”
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Serum albumin at 1 year predicts long-term renal outcome in lupus nephritis
Published in Lupus science & medicine (01-01-2018)“…ObjectivesThe study aimed to determine if serum albumin at 12 months predicts long-term renal outcome at 48 months. Data from the NYU SAMPLE (Specimen and…”
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Sociodemographic Differences in COVID-19 Pandemic Experiences Among Families in the United States
Published in JAMA network open (01-08-2023)“…Few population-based studies in the US collected individual-level data from families during the COVID-19 pandemic. To examine differences in COVID-19…”
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Opportunities for understanding the COVID-19 pandemic and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) program
Published in Frontiers in pediatrics (15-06-2023)“…Ongoing pediatric cohort studies offer opportunities to investigate the impact of the COVID-19 pandemic on children's health. With well-characterized data from…”
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