Search Results - "Bornkamp, B"

Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4–5 December 2014) by Musuamba, FT, Manolis, E, Holford, N, Cheung, SYA, Friberg, LE, Ogungbenro, K, Posch, M, Yates, JWT, Berry, S, Thomas, N, Corriol‐Rohou, S, Bornkamp, B, Bretz, F, Hooker, AC, Van der Graaf, PH, Standing, JF, Hay, J, Cole, S, Gigante, V, Karlsson, K, Dumortier, T, Benda, N, Serone, F, Das, S, Brochot, A, Ehmann, F, Hemmings, R, Rusten, I Skottheim

“…Inadequate dose selection for confirmatory trials is currently still one of the most challenging issues in drug development, as illustrated by high rates of…”
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Multiple comparison procedure and modeling: a versatile tool for evaluating dose-response relationships in veterinary pharmacology - a case study with furosemide by Bieth, B., Bornkamp, B., Toutain, C., Garcia, R., Mochel, J. P.

“…Congestive heart failure (CHF) is a leading cause of mortality with an increasing prevalence in human and canine populations. While furosemide is a loop…”
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A proposal for a new PhD level curriculum on quantitative methods for drug development by Jaki, T., Gordon, A., Forster, P., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L.V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A., Vonk, R., Koenig, F.

“…This paper provides an overview of “Improving Design, Evaluation and Analysis of early drug development Studies” (IDEAS), a European Commission–funded network…”
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Model-based dose finding under model uncertainty using general parametric models by Pinheiro, José, Bornkamp, Björn, Glimm, Ekkehard, Bretz, Frank

“…The statistical methodology for the design and analysis of clinical Phase II dose‐response studies, with related software implementation, is well developed for…”
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Stochastically ordered multiple regression by Bornkamp, Björn, Ickstadt, Katja, Dunson, David

“…In various application areas, prior information is available about the direction of the effects of multiple predictors on the conditional response…”
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Macro and micro diversity in land-mobile cellular radio telephony networks with discontinuous voice transmission by Bornkamp, B., Kegel, A., Prasad, R.

“…Signals in a macrocellular environment are subject to both shadow fading and multipath fading. The effects of shadow fading can be combated by using more than…”
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Uplink and downlink performance analysis of a cellular radio system using corner base stations and directional antennas by Bornkamp, B., Kegel, A., Prasad, R.

“…A mathematical model is developed to analyze the performance of a cellular radio system with a corner exited cellular concept. Such a concept is highly…”
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