Search Results - "Borniger, Jeremy"

Cancer neuroscience at the brain-body interface by Borniger, Jeremy C

“…Our approaches toward understanding cancer have evolved beyond cell-intrinsic and local microenvironmental changes within the tumor to encompass how the cancer…”
Get full text

Cancer as a homeostatic challenge: the role of the hypothalamus by Francis, Nikita, Borniger, Jeremy C.

“…The initiation, progression, and metastatic spread of cancer elicits diverse changes in systemic physiology. In this way, cancer represents a novel homeostatic…”
Get full text

Molecular Mechanisms of Cancer-Induced Sleep Disruption by Walker, 2nd, William H, Borniger, Jeremy C

“…Sleep is essential for health. Indeed, poor sleep is consistently linked to the development of systemic disease, including depression, metabolic syndrome, and…”
Get full text

Light at night, clocks and health: from humans to wild organisms by Dominoni, Davide M., Borniger, Jeremy C., Nelson, Randy J.

“…The increasing use of electric lights has modified the natural light environment dramatically, posing novel challenges to both humans and wildlife. Indeed,…”
Get full text

Roadmap for the Emerging Field of Cancer Neuroscience by Monje, Michelle, Borniger, Jeremy C., D’Silva, Nisha J., Deneen, Benjamin, Dirks, Peter B., Fattahi, Faranak, Frenette, Paul S., Garzia, Livia, Gutmann, David H., Hanahan, Douglas, Hervey-Jumper, Shawn L., Hondermarck, Hubert, Hurov, Jonathan B., Kepecs, Adam, Knox, Sarah M., Lloyd, Alison C., Magnon, Claire, Saloman, Jami L., Segal, Rosalind A., Sloan, Erica K., Sun, Xin, Taylor, Michael D., Tracey, Kevin J., Trotman, Lloyd C., Tuveson, David A., Wang, Timothy C., White, Ruth A., Winkler, Frank

“…Mounting evidence indicates that the nervous system plays a central role in cancer pathogenesis. In turn, cancers and cancer therapies can alter nervous system…”
Get full text

Sleep Disruption and Cancer: Chicken or the Egg? by Berisha, Adrian, Shutkind, Kyle, Borniger, Jeremy C

“…Sleep is a nearly ubiquitous phenomenon across the phylogenetic tree, highlighting its essential role in ensuring fitness across evolutionary time…”
Get full text

Hypocretin as a Hub for Arousal and Motivation by Tyree, Susan M, Borniger, Jeremy C, de Lecea, Luis

“…The lateral hypothalamus is comprised of a heterogeneous mix of neurons that serve to integrate and regulate sleep, feeding, stress, energy balance, reward,…”
Get full text

Neuroendocrine and Behavioral Consequences of Hyperglycemia in Cancer by Vasquez, Juan H, Borniger, Jeremy C

“…Abstract A hallmark of cancer is the disruption of cellular metabolism during the course of malignant growth. Major focus is now on how these cell-autonomous…”
Get full text

Peripheral Lipopolyssacharide Rapidly Silences REM-Active LHGABA Neurons by Borniger, Jeremy C., de Lecea, Luis

“…Immune factors (e.g., cytokines, chemokines) can alter the activity of neuronal circuits to promote “sickness behavior,” a suite of adaptive actions that…”
Get full text

Neuropeptides in Cancer: Friend and Foe? by Wu, Yue, Berisha, Adrian, Borniger, Jeremy C.

“…Neuropeptides are small regulatory molecules found throughout the body, most notably in the nervous, cardiovascular, and gastrointestinal systems. They serve…”
Get full text

Cancer as a tool for preclinical psychoneuroimmunology by Borniger, Jeremy C.

“…Cancer represents a novel homeostatic challenge to the host system. How the brain senses and responds to changes in peripheral physiology elicited by tumor…”
Get full text

Hypothalamic circuitry underlying stress-induced insomnia and peripheral immunosuppression by Li, Shi-Bin, Borniger, Jeremy C, Yamaguchi, Hiroshi, Hédou, Julien, Gaudilliere, Brice, de Lecea, Luis

“…The neural substrates of insomnia/hyperarousal induced by stress remain unknown. Here, we show that restraint stress leads to hyperarousal associated with…”
Get full text

Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior by Walker, William H., Borniger, Jeremy C., Gaudier-Diaz, Monica M., Hecmarie Meléndez-Fernández, O., Pascoe, Jordan L., Courtney DeVries, A., Nelson, Randy J.

“…The advent and wide-spread adoption of electric lighting over the past century has profoundly affected the circadian organization of physiology and behavior…”
Get full text

Leaping into the unknown by Borniger, Jeremy C

Get full text

Photoperiodic regulation of behavior: Peromyscus as a model system by Borniger, Jeremy C., Nelson, Randy J.

“…Winter and summer present vastly different challenges to animals living outside of the tropics. To survive and reproduce, individuals must anticipate seasonal…”
Get full text

Acute dim light at night increases body mass, alters metabolism, and shifts core body temperature circadian rhythms by Borniger, Jeremy C, Maurya, Santosh K, Periasamy, Muthu, Nelson, Randy J

“…The circadian system is primarily entrained by the ambient light environment and is fundamentally linked to metabolism. Mounting evidence suggests a causal…”
Get more information

Time-Restricted Feeding Alters the Innate Immune Response to Bacterial Endotoxin by Cissé, Yasmine M, Borniger, Jeremy C, Lemanski, Elise, Walker, 2nd, William H, Nelson, Randy J

“…An important entraining signal for the endogenous circadian clock, independent of light, is food intake. The circadian and immune systems are linked; forced…”
Get full text

A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non-metastatic Breast Cancer by Borniger, Jeremy C., Walker II, William H., Surbhi, Emmer, Kathryn M., Zhang, Ning, Zalenski, Abigail A., Muscarella, Stevie L., Fitzgerald, Julie A., Smith, Alexandra N., Braam, Cornelius J., TinKai, Tial, Magalang, Ulysses J., Lustberg, Maryam B., Nelson, Randy J., DeVries, A. Courtney

“…We investigated relationships among immune, metabolic, and sleep abnormalities in mice with non-metastatic mammary cancer. Tumor-bearing mice displayed…”
Get full text

The role of PHOX2B‐derived astrocytes in chemosensory control of breathing and sleep homeostasis by Czeisler, Catherine M., Silva, Talita M., Fair, Summer R., Liu, Jillian, Tupal, Srinivasan, Kaya, Behiye, Cowgill, Aaron, Mahajan, Salil, Silva, Phelipe E., Wang, Yangyang, Blissett, Angela R., Göksel, Mustafa, Borniger, Jeremy C., Zhang, Ning, Fernandes‐Junior, Silvio A., Catacutan, Fay, Alves, Michele J., Nelson, Randy J., Sundaresean, Vishnu, Rekling, Jens, Takakura, Ana C., Moreira, Thiago S., Otero, José J.

“…Key points The embryonic PHOX2B‐progenitor domain generates neuronal and glial cells which together are involved in chemosensory control of breathing and sleep…”
Get full text

The Heart´s rhythm 'n' blues: Sex differences in circadian variation patterns of vagal activity vary by depressive symptoms in predominantly healthy employees by Jarczok, Marc N, Aguilar-Raab, Corina, Koenig, Julian, Kaess, Michael, Borniger, Jeremy C, Nelson, Randy J, Hall, Martica, Ditzen, Beate, Thayer, Julian F, Fischer, Joachim E

“…Successful regulation of emotional states is positively associated to mental health, while difficulties in regulating emotions are negatively associated to…”
Get more information