Search Results - "Bornand, David"

Tobacco Alkaloid Assessment in a DSS-Induced Colitis Mouse Model with a Fully Humanized Immune System by Verhaeghe, Catherine, Talikka, Marja, Sewer, Alain, Sierro, Nicolas, Auberson, Mehdi, Peric, Dariusz, Bornand, David, Dulize, Remi, Guedj, Emmanuel, Nef, Patrick, Tabruyn, Sebastien P, Hoeng, Julia, Peitsch, Manuel C, Lo Sasso, Giuseppe

“…Inflammatory bowel disease (IBD) refers to chronic intestinal immune-mediated diseases including two main disease manifestations: ulcerative colitis (UC) and…”
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The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts by Lo Sasso, Giuseppe, Phillips, Blaine W., Sewer, Alain, Battey, James N. D., Kondylis, Athanasios, Talikka, Marja, Titz, Bjoern, Guedj, Emmanuel, Peric, Dariusz, Bornand, David, Dulize, Remi, Merg, Celine, Corciulo, Maica, Ouadi, Sonia, Yanuar, Rendy, Tung, Ching Keong, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia

“…Exposure to cigarette smoke (CS) causes detrimental health effects, increasing the risk of cardiovascular, pulmonary diseases and carcinogenesis in exposed…”
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Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis by Ruiz Castro, Pedro A, Kogel, Ulrike, Lo Sasso, Giuseppe, Phillips, Blaine W, Sewer, Alain, Titz, Bjorn, Garcia, Llenalia, Kondylis, Athanasios, Guedj, Emmanuel, Peric, Dariusz, Bornand, David, Dulize, Remi, Merg, Celine, Corciulo, Maica, Ivanov, Nikolai V, Peitsch, Manuel C, Hoeng, Julia

“…Inflammatory bowel disease (IBD) is the collective term for chronic immune-mediated diseases of unknown, multifactorial etiology, arising from the interplay…”
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Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells by Marescotti, Diego, Mathis, Carole, Belcastro, Vincenzo, Leroy, Patrice, Acali, Stefano, Martin, Florian, Dulize, Rémi, Bornand, David, Peric, Dariusz, Guedj, Emmanuel, Ortega Torres, Laura, Biasioli, Matteo, Fuhrimann, Matthieu, Fernandes, Estela, Frauendorfer, Felix, Gonzalez Suarez, Ignacio, Sciuscio, Davide, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia

“…[Display omitted] •A 3-step approach combining 1) real-time cytotoxicity, 2) high-content screening and 3) gene expression analysis was developed in NHBE…”
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A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products by Sewer, Alain, Zanetti, Filippo, Iskandar, Anita R., Guedj, Emmanuel, Dulize, Remi, Peric, Dariusz, Bornand, David, Mathis, Carole, Martin, Florian, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia

“…[Display omitted] •This meta-analysis evaluated 12 miRNA expression datasets from aerodigestive tissues.•Treatments included cigarette smoke (CS) and…”
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Elementary abelian subgroups in p-groups with a cyclic derived subgroup by Bornand, David

“…Let p be an arbitrary prime number and let P be a finite p-group. Let A p ( P ) be the partially ordered set (poset for short) of all non-trivial elementary…”
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Counterexamples to a fiber theorem by Bornand, David

“…We exhibit a counterexample to a fiber theorem stated by F. Fumagalli in [Francesco Fumagalli, On the homotopy type of the Quillen complex of finite soluble…”
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The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product by van der Toorn, Marco, Sewer, Alain, Marescotti, Diego, Johne, Stephanie, Baumer, Karin, Bornand, David, Dulize, Remi, Merg, Celine, Corciulo, Maica, Scotti, Elena, Pak, Claudius, Leroy, Patrice, Guedj, Emmanuel, Ivanov, Nikolai, Martin, Florian, Peitsch, Manuel, Hoeng, Julia, Luettich, Karsta

“…Cigarette smoking is the leading cause of preventable lung cancer (LC). Reduction of harmful constituents by heating rather than combusting tobacco may have…”
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Blood and urine multi-omics analysis of the impact of e-vaping, smoking, and cessation: from exposome to molecular responses by Poussin, Carine, Titz, Bjoern, Xiang, Yang, Baglia, Laurel, Berg, Rachel, Bornand, David, Choukrallah, Mohammed-Amin, Curran, Timothy, Dijon, Sophie, Dossin, Eric, Dulize, Remi, Etter, Doris, Fatarova, Maria, Medlin, Loyse Felber, Haiduc, Adrian, Kishazi, Edina, Kolli, Aditya R., Kondylis, Athanasios, Kottelat, Emmanuel, Laszlo, Csaba, Lavrynenko, Oksana, Eb-Levadoux, Yvan, Nury, Catherine, Peric, Dariusz, Rizza, Melissa, Schneider, Thomas, Guedj, Emmanuel, Calvino, Florian, Sierro, Nicolas, Guy, Philippe, Ivanov, Nikolai V., Picavet, Patrick, Spinelli, Sherry, Hoeng, Julia, Peitsch, Manuel C.

“…Cigarette smoking is a major preventable cause of morbidity and mortality. While quitting smoking is the best option, switching from cigarettes to…”
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In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells by Poussin, Carine, Laurent, Alexandra, Kondylis, Athanasios, Marescotti, Diego, van der Toorn, Marco, Guedj, Emmanuel, Goedertier, Didier, Acali, Stefano, Pak, Claudius, Dulize, Rémi, Baumer, Karine, Peric, Dariusz, Maluenda, Elodie, Bornand, David, Suarez, Ignacio Gonzalez, Schlage, Walter K., Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia

“…Cigarette smoking causes cardiovascular diseases. Heating tobacco instead of burning it reduces the amount of toxic compounds in the aerosol and may exert a…”
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A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment by Titz, Bjoern, Kogel, Ulrike, Martin, Florian, Schlage, Walter K., Xiang, Yang, Nury, Catherine, Dijon, Sophie, Baumer, Karine, Peric, Dariusz, Bornand, David, Dulize, Remi, Phillips, Blaine, Leroy, Patrice, Vuillaume, Gregory, Lebrun, Stefan, Elamin, Ashraf, Guedj, Emmanuel, Trivedi, Keyur, Ivanov, Nikolai V., Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia

“…Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a…”
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Corrigendum to “The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product” published in Toxicology in Vitro, Volume 50, August 2018, Pages 95–108 by van der Toorn, Marco, Sewer, Alain, Marescotti, Diego, Johne, Stephanie, Baumer, Karin, Bornand, David, Dulize, Remi, Merg, Celine, Corciulo, Maica, Scotti, Elena, Pak, Claudius, Leroy, Patrice, Guedj, Emmanuel, Ivanov, Nikolai, Martin, Florian, Peitsch, Manuel, Hoeng, Julia, Luettich, Karsta

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A 6-month inhalation toxicology study in Apoe−/− mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract by Wong, Ee Tsin, Szostak, Justyna, Titz, Bjoern, Lee, Tom, Wong, Sin Kei, Lavrynenko, Oksana, Merg, Celine, Corciulo, Maica, Simicevic, Jovan, Auberson, Mehdi, Peric, Dariusz, Dulize, Remi, Bornand, David, Loh, Guo Jie, Lee, Kyeonghee Monica, Zhang, Jingjie, Miller, John H., Schlage, Walter K., Guedj, Emmanuel, Schneider, Thomas, Phillips, Blaine, Leroy, Patrice, Choukrallah, Mohamed Amin, Sierro, Nicolas, Buettner, Ansgar, Xiang, Yang, Kuczaj, Arkadiusz, Ivanov, Nikolai V., Luettich, Karsta, Vanscheeuwijck, Patrick, Peitsch, Manuel C., Hoeng, Julia

“…Cigarette smoking is the major cause of chronic obstructive pulmonary disease. Considerable attention has been paid to the reduced harm potential of…”
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How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models by Marescotti, Diego, Serchi, Tommaso, Luettich, Karsta, Xiang, Yang, Moschini, Elisa, Talikka, Marja, Martin, Florian, Baumer, Karine, Dulize, Remi, Peric, Dariusz, Bornand, David, Guedj, Emmanuel, Sewer, Alain, Cambier, Sebastian, Contal, Servane, Chary, Aline, Gutleb, Arno C, Frentzel, Stefan, Ivanov, Nikoloai V, Peitsch, Manuel C, Hoeng, Julia

“…To more accurately model inhalation toxicity in vitro, we developed a tetra-culture system that combines lung alveolar epithelial cells, endothelial cells,…”
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Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data by Xiang, Yang, Luettich, Karsta, Martin, Florian, Battey, James N D, Trivedi, Keyur, Neau, Laurent, Wong, Ee Tsin, Guedj, Emmanuel, Dulize, Remi, Peric, Dariusz, Bornand, David, Ouadi, Sonia, Sierro, Nicolas, Büttner, Ansgar, Ivanov, Nikolai V, Vanscheeuwijck, Patrick, Hoeng, Julia, Peitsch, Manuel C

“…Mice, especially A/J mice, have been widely employed to elucidate the underlying mechanisms of lung tumor formation and progression and to derive…”
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A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products by Sewer, Alain, Zanetti, Filippo, Iskandar, Anita R, Guedj, Emmanuel, Dulize, Remi, Peric, Dariusz, Bornand, David, Mathis, Carole, Martin, Florian, Ivanov, Nikolai V, Peitsch, Manuel C, Hoeng, Julia

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Fears for the O level by BORNAND, DAVID

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