Search Results - "Bornancin, F"
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Retinal layers and symptoms and inflammation in schizophrenia
Published in European archives of psychiatry and clinical neuroscience (01-08-2024)“…Schizophrenia is a neurodevelopmental disorder that affects brain structure and function. The retina, as well as the brain, consists of neuronal and glial…”
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Phosphorylation of Protein Kinase C-α on Serine 657 Controls the Accumulation of Active Enzyme and Contributes to Its Phosphatase-resistant State
Published in The Journal of biological chemistry (07-02-1997)“…Serine 657 in protein kinase C-α (PKCα) is a site of phosphorylation on expression of the recombinant protein in mammalian cells. To define the function of…”
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Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Cα
Published in Current biology (01-09-1996)“…Background It has been widely reported that multisite phosphorylation plays an essential role in the regulation of protein kinases. However, our understanding…”
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4
Threonine-497 is a critical site for permissive activation of protein kinase Cα
Published in Biochemical journal (15-07-1994)“…Phosphorylation of the region containing Thr-494, Thr-495 and Thr-497, present in the catalytic domain of protein kinase C alpha (PKC alpha), is a preliminary…”
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5
Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases
Published in Molecular cell (05-03-2020)“…Metacaspases and paracaspases are proteases that were first identified as containing a caspase-like structural fold ( Uren et al., 2000 ). Like caspases, meta-…”
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Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases
Published in The Journal of biological chemistry (28-11-2003)“…The immunomodulatory drug FTY720 is phosphorylated in vivo , and the resulting FTY720 phosphate as a ligand for sphingosine-1-phosphate receptors is…”
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Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720
Published in Blood (15-02-2006)“…FTY720, a potent immunomodulatory drug in phase 2/3 clinical trials, induces rapid and reversible sequestration of lymphocytes into secondary lymphoid organs,…”
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ADP-ribosylation of Gs by cholera toxin is potentiated by agonist activation of beta-adrenergic receptors in the absence of GTP
Published in The Journal of biological chemistry (15-08-1993)“…Purified Gs is a substrate for ADP-ribosylation catalyzed by cholera toxin (CTx). In S49 cyc- membranes complemented with in vitro translated Gs alpha, the…”
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Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1β and TNF-α induced production of inflammatory mediators
Published in Cellular signalling (01-10-2005)“…Sphingosine-1-phosphate, a lipid mediator produced by sphingosine kinases, regulates diverse cellular processes, ranging from cell growth and survival to…”
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10
Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice
Published in Biochemical and biophysical research communications (15-08-2008)“…Ceramide kinase-like (CerkL) is the most recently identified member of the sphingolipid metabolizing enzyme family. This protein is believed to have ceramide…”
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The role of sphingosine and ceramide kinases in inflammatory responses
Published in Immunology letters (31-01-2005)“…The 1-phosphates of sphingosine and ceramide (S1P and C1P) have emerged as key representatives of a new group of lipid signalling molecules. S1P is known to…”
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Imaging Protein Kinase Cα Activation in Cells
Published in Science (American Association for the Advancement of Science) (26-03-1999)“…Spatially resolved fluorescence resonance energy transfer (FRET) measured by fluorescence lifetime imaging microscopy (FLIM), provides a method for tracing the…”
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Normal neutrophil functions in sphingosine kinase type 1 and 2 knockout mice
Published in Immunology Letters (15-03-2007)“…Abstract Sphingosine kinase (SPHK) has been implicated as an important element in neutrophil responses to diverse stimulatory agents. To get more insight into…”
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Early Activation of Sphingosine Kinase in Mast Cells and Recruitment to FcεRI Are Mediated by Its Interaction with Lyn Kinase
Published in Molecular and Cellular Biology (01-10-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multisite dephosphorylation and desensitization of conventional protein kinase C isotypes
Published in Biochemical journal (01-09-1999)“…The generation of antisera specific for the priming phosphorylation sites on protein kinase Calpha (PKCalpha) has permitted analysis of the dephosphorylation…”
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16
Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain
Published in Biochemical and biophysical research communications (26-11-2004)“…The N-terminus of ceramide kinase (CERK) is thought to be myristoylated and to contain a pleckstrin homology (PH) domain. We found that deletion of this region…”
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12-O-Tetradecanoylphorbol-13-acetate-induced Dephosphorylation of Protein Kinase Cα Correlates with the Presence of a Membrane-associated Protein Phosphatase 2A Heterotrimer
Published in The Journal of biological chemistry (20-12-1996)“…Protein kinase C signaling is desensitized through a combination of dephosphorylation and proteolysis in intact cells. The process of dephosphorylation is…”
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The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation
Published in Biochemical journal (01-08-1998)“…Dominant negative properties are conferred on protein kinase (PK) Calpha by mutation of the phosphorylation site in the activation loop of the kinase domain…”
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20
Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha
Published in Current biology (01-09-1996)“…It has been widely reported that multisite phosphorylation plays an essential role in the regulation of protein kinases. However, our understanding of how…”
Get full text
Journal Article