Search Results - "Bornancin, F"

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    Phosphorylation of Protein Kinase C-α on Serine 657 Controls the Accumulation of Active Enzyme and Contributes to Its Phosphatase-resistant State by Bornancin, Frédéric, Parker, Peter J.

    Published in The Journal of biological chemistry (07-02-1997)
    “…Serine 657 in protein kinase C-α (PKCα) is a site of phosphorylation on expression of the recombinant protein in mammalian cells. To define the function of…”
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    Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Cα by Bornancin, Frédéric, Parker, Peter J.

    Published in Current biology (01-09-1996)
    “…Background It has been widely reported that multisite phosphorylation plays an essential role in the regulation of protein kinases. However, our understanding…”
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    Threonine-497 is a critical site for permissive activation of protein kinase Cα by CAZAUBON, S, BORNANCIN, F, PARKER, P. J

    Published in Biochemical journal (15-07-1994)
    “…Phosphorylation of the region containing Thr-494, Thr-495 and Thr-497, present in the catalytic domain of protein kinase C alpha (PKC alpha), is a preliminary…”
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    Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases by Billich, Andreas, Bornancin, Frederic, Dévay, Piroska, Mechtcheriakova, Diana, Urtz, Nicole, Baumruker, Thomas

    Published in The Journal of biological chemistry (28-11-2003)
    “…The immunomodulatory drug FTY720 is phosphorylated in vivo , and the resulting FTY720 phosphate as a ligand for sphingosine-1-phosphate receptors is…”
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    Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720 by Zemann, Barbara, Kinzel, Bernd, Müller, Matthias, Reuschel, Roland, Mechtcheriakova, Diana, Urtz, Nicole, Bornancin, Frédéric, Baumruker, Thomas, Billich, Andreas

    Published in Blood (15-02-2006)
    “…FTY720, a potent immunomodulatory drug in phase 2/3 clinical trials, induces rapid and reversible sequestration of lymphocytes into secondary lymphoid organs,…”
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    ADP-ribosylation of Gs by cholera toxin is potentiated by agonist activation of beta-adrenergic receptors in the absence of GTP by BORNANCIN, F, AUDIGIER, Y, CHABRE, M

    Published in The Journal of biological chemistry (15-08-1993)
    “…Purified Gs is a substrate for ADP-ribosylation catalyzed by cholera toxin (CTx). In S49 cyc- membranes complemented with in vitro translated Gs alpha, the…”
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    Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1β and TNF-α induced production of inflammatory mediators by Billich, Andreas, Bornancin, Frédéric, Mechtcheriakova, Diana, Natt, François, Huesken, Dieter, Baumruker, Thomas

    Published in Cellular signalling (01-10-2005)
    “…Sphingosine-1-phosphate, a lipid mediator produced by sphingosine kinases, regulates diverse cellular processes, ranging from cell growth and survival to…”
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    Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice by Graf, Christine, Niwa, Satoru, Müller, Matthias, Kinzel, Bernd, Bornancin, Frédéric

    “…Ceramide kinase-like (CerkL) is the most recently identified member of the sphingolipid metabolizing enzyme family. This protein is believed to have ceramide…”
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    The role of sphingosine and ceramide kinases in inflammatory responses by Baumruker, Thomas, Bornancin, Frédéric, Billich, Andreas

    Published in Immunology letters (31-01-2005)
    “…The 1-phosphates of sphingosine and ceramide (S1P and C1P) have emerged as key representatives of a new group of lipid signalling molecules. S1P is known to…”
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    Imaging Protein Kinase Cα Activation in Cells by Ng, Tony, Squire, Anthony, Hansra, Gurdip, Bornancin, Frederic, Prevostel, Corinne, Hanby, Andrew, Harris, William, Barnes, Diana, Schmidt, Sandra, Mellor, Harry, Philippe I. H. Bastiaens, Parker, Peter J.

    “…Spatially resolved fluorescence resonance energy transfer (FRET) measured by fluorescence lifetime imaging microscopy (FLIM), provides a method for tracing the…”
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    Normal neutrophil functions in sphingosine kinase type 1 and 2 knockout mice by Zemann, Barbara, Urtz, Nicole, Reuschel, Roland, Mechtcheriakova, Diana, Bornancin, Frédéric, Badegruber, Rudolf, Baumruker, Thomas, Billich, Andreas

    Published in Immunology Letters (15-03-2007)
    “…Abstract Sphingosine kinase (SPHK) has been implicated as an important element in neutrophil responses to diverse stimulatory agents. To get more insight into…”
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    Early Activation of Sphingosine Kinase in Mast Cells and Recruitment to FcεRI Are Mediated by Its Interaction with Lyn Kinase by Urtz, Nicole, Olivera, Ana, Bofill-Cardona, Elisa, Csonga, Robert, Billich, Andreas, Mechtcheriakova, Diana, Bornancin, Frederic, Woisetschläger, Max, Rivera, Juan, Baumruker, Thomas

    Published in Molecular and Cellular Biology (01-10-2004)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Multisite dephosphorylation and desensitization of conventional protein kinase C isotypes by Hansra, G, Garcia-Paramio, P, Prevostel, C, Whelan, R D, Bornancin, F, Parker, P J

    Published in Biochemical journal (01-09-1999)
    “…The generation of antisera specific for the priming phosphorylation sites on protein kinase Calpha (PKCalpha) has permitted analysis of the dephosphorylation…”
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    Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain by Carré, Adeline, Graf, Christine, Stora, Samantha, Mechtcheriakova, Diana, Csonga, Robert, Urtz, Nicole, Billich, Andreas, Baumruker, Thomas, Bornancin, Frédéric

    “…The N-terminus of ceramide kinase (CERK) is thought to be myristoylated and to contain a pleckstrin homology (PH) domain. We found that deletion of this region…”
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    12-O-Tetradecanoylphorbol-13-acetate-induced Dephosphorylation of Protein Kinase Cα Correlates with the Presence of a Membrane-associated Protein Phosphatase 2A Heterotrimer by Hansra, Gurdip, Bornancin, Frederic, Whelan, Richard, Hemmings, Brian A., Parker, Peter J.

    Published in The Journal of biological chemistry (20-12-1996)
    “…Protein kinase C signaling is desensitized through a combination of dephosphorylation and proteolysis in intact cells. The process of dephosphorylation is…”
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    The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation by Garcia-Paramio, P, Cabrerizo, Y, Bornancin, F, Parker, P J

    Published in Biochemical journal (01-08-1998)
    “…Dominant negative properties are conferred on protein kinase (PK) Calpha by mutation of the phosphorylation site in the activation loop of the kinase domain…”
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    Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha by Bornancin, F, Parker, P J

    Published in Current biology (01-09-1996)
    “…It has been widely reported that multisite phosphorylation plays an essential role in the regulation of protein kinases. However, our understanding of how…”
    Get full text
    Journal Article