Search Results - "Born, Timothy L."

The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins by Baranova, Ancha, Ivanov, Dmitry, Petrash, Nadezda, Pestova, Anya, Skoblov, Mikhail, Kelmanson, Ilya, Shagin, Dmitry, Nazarenko, Svetlana, Geraymovych, Elena, Litvin, Oxana, Tiunova, Anya, Born, Timothy L, Usman, Natalia, Staroverov, Dmitry, Lukyanov, Sergey, Panchin, Yury

“…We have cloned the genes PANX1, PANX2 and PANX3, encoding putative gap junction proteins homologous to invertebrate innexins, which constitute a new family of…”
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A genomic and proteomic study of the spectrum of nonalcoholic fatty liver disease by YOUNOSSI, Zobair M, BARANOVA, Ancha, ONG, Janus P, GOODMAN, Zachary, CHANDHOKE, Vikas, ZIEGLER, Katharine, DEL GIACCO, Luca, SCHLAUCH, Karen, BORN, Timothy L, ELARINY, Hazem, GORRETA, Francesco, VANMETER, Amy, YOUNOSZAI, Abraham

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and some of its forms are progressive. This study describes the profiling of…”
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Conversion of polycyclic aromatic hydrocarbons by Sphingomonas sp. VKM B-2434 by Baboshin, Mikhail, Akimov, Vladimir, Baskunov, Boris, Born, Timothy L, Khan, Shahamat U, Golovleva, Ludmila

“…A versatile bacterial strain able to convert polycyclic aromatic hydrocarbons (PAHs) was isolated, and a conversion by the isolate of both individual…”
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Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis by Born, Timothy L, Blanchard, John S

“…Within the past 18 months work has continued on the structure and mechanisms of enzymes involved in the diaminopimelic acid/lysine biosynthetic pathway. A…”
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Enzyme-Catalyzed Acylation of Homoserine:  Mechanistic Characterization of the Escherichia coli metA-Encoded Homoserine Transsuccinylase by Born, Timothy L, Blanchard, John S

“…The first unique step in bacterial and plant methionine biosynthesis involves the activation of the γ-hydroxyl of homoserine. In Escherichia coli, this…”
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Enzyme-Catalyzed Acylation of Homoserine:  Mechanistic Characterization of the Haemophilus influenzae met2-Encoded Homoserine Transacetylase by Born, Timothy L, Franklin, Matthew, Blanchard, John S

“…The first unique step in bacterial and plant methionine biosynthesis involves the acylation of the γ-hydroxyl of homoserine. In Haemophilus influenzae,…”
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Purification and characterization of Thermotoga maritima homoserine transsuccinylase indicates it is a transacetylase by GOUDARZI, Maryam, BORN, Timothy L

“…The methionine biosynthetic pathway found in bacteria is controlled at the first step, acylation of the gamma-hydroxyl of homoserine. This reaction is…”
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Protein profile of osteoarthritic human articular cartilage using tandem mass spectrometry by Garcia, Benjamin A., Platt, Mark D., Born, Timothy L., Shabanowitz, Jeffrey, Marcus, Norman A., Hunt, Donald F.

“…Articular cartilage contains both chondrocyte cells and extracellular matrix (ECM) components. Currently, comprehensive information concerning the protein…”
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Substrate analysis of homoserine acyltransferase from Bacillus cereus by Ziegler, Katharine, Yusupov, Muzaffar, Bishop, Barney, Born, Timothy L.

“…Substrate specificity within the family of enzymes designated as homoserine transsuccinylases is variable, with some organisms utilizing succinyl-CoA and other…”
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Identification of Catalytic Cysteine, Histidine, and Lysine Residues in Escherichia coli Homoserine Transsuccinylase by Ziegler, Katharine, Noble, Schroeder M, Mutumanje, Elissa, Bishop, Barney, Huddler, Donald P, Born, Timothy L

“…Homoserine transsuccinylase catalyzes the succinylation of homoserine in several bacterial species, the first unique step in methionine biosynthesis in these…”
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Use of surface-enhanced laser desorption/ionization -time of flight to explore bacterial proteomes by Barzaghi, Dagania, Isbister, Jenefir D., Lauer, Kimberly P., Born, Timothy L.

“…Surface‐enhanced laser desorption/ionization (SELDI)‐time of flight is a recent technology that allows proteomic analysis with limited material requirements…”
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Hydrolysis of N-Succinyl-l,l-diaminopimelic Acid by the Haemophilus influenzae dapE-Encoded Desuccinylase:  Metal Activation, Solvent Isotope Effects, and Kinetic Mechanism by Born, Timothy L, Zheng, Renjian, Blanchard, John S

“…Hydrolysis of N-succinyl-l,l-diaminopimelic acid by the dapE-encoded desuccinylase is required for the bacterial synthesis of lysine and meso-diaminopimelic…”
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4-(Fluoromethyl)phenyl Phosphate Acts as a Mechanism-based Inhibitor of Calcineurin (∗) by Born, Timothy L., Myers, Jason K., Widlanski, Theodore S., Rusnak, Frank

“…The compound 4-(fluoromethyl)phenyl phosphate (FMPP), recently shown to be a mechanism-based inhibitor of prostatic acid phosphatase (Myers, J. K., and…”
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Functional substitution of alternative homoserine acyltransferases in E. coli by Yusupov, Muzaffar, Born, Timothy L

“…Homoserine transsuccinylase (HTS) is a bacterial enzyme that catalyzes the first unique step in methionine biosynthesis. Since methionine is an essential amino…”
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Acetylation of homoserine is required for methionine biosynthesis in Streptococcus pneumoniae by Nguyen, Minh, Born, Timothy L

“…The metabolite homoserine occupies an important juncture between methionine, lysine, threonine, and isoleucine biosynthesis, and its fate is tightly…”
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Conversion of polycyclic aromatic hydrocarbons by Sphingomonas sp. VKM B-2434 by BABOSHIN, Mikhail, AKIMOV, Vladimir, BASKUNOV, Boris, BORN, Timothy L, KHAN, Shahamat U, GOLOVLEVA, Ludmila

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Inhibition of calcineurin by cyclosporin A-cyclophilin requires calcineurin B by Haddy, Alice, Swanson, Selene K.-H., Born, Timothy L., Rusnak, Frank

“…The interaction of the immunosuppressive complex cyclosporin A-cyclophilin (CsA-CyP) with the Ca 2+/calmodulin-dependent protein phosphatase calcineurin is…”
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The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins by BARANOVA, Ancha, IVANOV, Dmitry, TIUNOVA, Anya, BORN, Timothy L, USMAN, Natalia, STAROVEROV, Dmitry, LUKYANOV, Sergey, PANCHIN, Yury, PETRASH, Nadezda, PESTOVA, Anya, SKOBLOV, Mikhail, KELMANSON, Ilya, SHAGIN, Dmitry, NAZARENKO, Svetlana, GERAYMOVYCH, Elena, LITVIN, Oxana

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