Search Results - "Born, Donald"

Iron and Alzheimer's Disease: From Pathology to Imaging by Tran, Dean, DiGiacomo, Phillip, Born, Donald E, Georgiadis, Marios, Zeineh, Michael

“…Alzheimer's disease (AD) is a debilitating brain disorder that afflicts millions worldwide with no effective treatment. Currently, AD progression has primarily…”
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Cytodifferentiation of pituitary tumors influences pathogenesis and cavernous sinus invasion by Asmaro, Karam, Zhang, Michael, Rodrigues, Adrian J, Mohyeldin, Ahmed, Vigo, Vera, Nernekli, Kerem, Vogel, Hannes, Born, Donald E, Katznelson, Laurence, Fernandez-Miranda, Juan C

“…Pituitary tumors (PTs) continue to present unique challenges given their proximity to the cavernous sinus, whereby invasive behavior can limit the extent of…”
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Why do inguinal hernia patients have pain? Histology points to compression neuropathy by Wright, Robert, MD, Born, Donald E., MD PhD, D'Souza, Natasha, Hurd, Larissa, Gill, Rachel, Wright, Daniel

“…Abstract Purpose The purpose of this study is to describe the known soft tissue neuro-histology factors associated with compression neuropathy in relation to…”
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Macrophage Exclusion after Radiation Therapy (MERT): A First in Human Phase I/II Trial using a CXCR4 Inhibitor in Glioblastoma by Thomas, Reena P, Nagpal, Seema, Iv, Michael, Soltys, Scott G, Bertrand, Sophie, Pelpola, Judith S, Ball, Robyn, Yang, Jaden, Sundaram, Vandana, Lavezo, Jonathan, Born, Donald, Vogel, Hannes, Brown, J Martin, Recht, Lawrence D

“…Preclinical studies have demonstrated that postirradiation tumor revascularization is dependent on a stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine…”
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Reduced Fascicle Area Demonstrated in Ilioinguinal Nerves Resected from Primary Inguinal Herniorrhaphy Patients as Evidence of Compression Neuropathy by Wright, Robert, Born, Donald E., Sanders, Troy, Landes, Jordan, Salisbury, Troy, Kumar, Anjali S., Horne, Makena

“…Background and Aim. Previous studies have reported 63% of primary inguinal hernia patients present with apparent enlargement of the ilioinguinal nerve beyond…”
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Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes by Kumar, Akash, Boyle, Evan A, Tokita, Mari, Mikheev, Andrei M, Sanger, Michelle C, Girard, Emily, Silber, John R, Gonzalez-Cuyar, Luis F, Hiatt, Joseph B, Adey, Andrew, Lee, Choli, Kitzman, Jacob O, Born, Donald E, Silbergeld, Daniel L, Olson, James M, Rostomily, Robert C, Shendure, Jay

“…The extent of intratumoral mutational heterogeneity remains unclear in gliomas, the most common primary brain tumors, especially with respect to point…”
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HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells by MATHIEU, Julie, ZHAN ZHANG, TEWARI, Muneesh, LIU, Alvin, VESSELLA, Robert, ROSTOMILY, Robert, BORN, Donald, HORWITZ, Marshall, WARE, Carol, BLAU, C. Anthony, CLEARY, MicheleA, RICH, Jeremy N, WENYU ZHOU, RUOHOLA-BAKER, Hannele, WANG, Amy J, HEDDLESTON, John M, PINNA, Claudia M. A, HUBAUD, Alexis, STADLER, Bradford, CHOI, Michael, BAR, Merav

“…Low oxygen levels have been shown to promote self-renewal in many stem cells. In tumors, hypoxia is associated with aggressive disease course and poor clinical…”
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Neuroinvasive Francisella tularensis Infection: Report of 2 Cases and Review of the Literature by Cash-Goldwasser, Shama, Beeson, Amy, Marzec, Natalie, Ho, Dora Y, Hogan, Catherine A, Budvytiene, Indre, Banaei, Niaz, Born, Donald E, Gephart, Melanie H, Patel, Jatinbhai, Dietrich, Elizabeth A, Nelson, Christina A

“…Abstract Background Neuroinvasive infection with Francisella tularensis, the causative agent of tularemia, is rare. Establishing clinical suspicion is…”
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Mycobacterium marinum Infection of Adult Zebrafish Causes Caseating Granulomatous Tuberculosis and Is Moderated by Adaptive Immunity by Swaim, Laura E, Connolly, Lynn E, Volkman, Hannah E, Humbert, Olivier, Born, Donald E, Ramakrishnan, Lalita

“…The zebrafish, a genetically tractable model vertebrate, is naturally susceptible to tuberculosis caused by Mycobacterium marinum, a close genetic relative of…”
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Imaging crossing fibers in mouse, pig, monkey, and human brain using small-angle X-ray scattering by Georgiadis, Marios, Menzel, Miriam, Reuter, Jan A, Born, Donald E, Kovacevich, Sophie R, Alvarez, Dario, Taghavi, Hossein Moein, Schroeter, Aileen, Rudin, Markus, Gao, Zirui, Guizar-Sicairos, Manuel, Weiss, Thomas M, Axer, Markus, Rajkovic, Ivan, Zeineh, Michael M

“…Myelinated axons (nerve fibers) efficiently transmit signals throughout the brain via action potentials. Multiple methods that are sensitive to axon…”
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Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA by Costales, Cristina, Sahoo, Malaya K, Huang, ChunHong, Guimaraes, Carolina V, Born, Donald, Kushner, Lauren, Gans, Hayley A, Doan, Thuy A, Pinsky, Benjamin A

“…We report a fatal case of vaccine-associated measles encephalitis in an immunocompromised child in California, USA. The infection was confirmed by whole-genome…”
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MULTIMODALITY TREATMENT OF BRAIN ARTERIOVENOUS MALFORMATIONS WITH MICROSURGERY AFTER EMBOLIZATION WITH ONYX: SINGLE-CENTER EXPERIENCE AND TECHNICAL NUANCES by Natarajan, Sabareesh K., Ghodke, Basavaraj, Britz, Gavin W., Born, Donald E., Sekhar, Laligam N.

“…OBJECTIVETo report our experience with the treatment of brain arteriovenous malformations (AVM) with microsurgical resection after embolization with Onyx…”
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Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients by Adair, Jennifer E, Johnston, Sandra K, Mrugala, Maciej M, Beard, Brian C, Guyman, Laura A, Baldock, Anne L, Bridge, Carly A, Hawkins-Daarud, Andrea, Gori, Jennifer L, Born, Donald E, Gonzalez-Cuyar, Luis F, Silbergeld, Daniel L, Rockne, Russell C, Storer, Barry E, Rockhill, Jason K, Swanson, Kristin R, Kiem, Hans-Peter

“…Temozolomide (TMZ) is one of the most potent chemotherapy agents for the treatment of glioblastoma. Unfortunately, almost half of glioblastoma tumors are TMZ…”
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Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status by Baldock, Anne L., Yagle, Kevin, Born, Donald E., Ahn, Sunyoung, Trister, Andrew D., Neal, Maxwell, Johnston, Sandra K., Bridge, Carly A., Basanta, David, Scott, Jacob, Malone, Hani, Sonabend, Adam M., Canoll, Peter, Mrugala, Maciej M., Rockhill, Jason K., Rockne, Russell C., Swanson, Kristin R.

“…Background Glioblastomas with a specific mutation in the isocitrate dehydrogenase 1 (IDH1) gene have a better prognosis than gliomas with wild-type IDH1…”
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Phosphoproteomic and Kinomic Signature of Clinically Aggressive Grade I (1.5) Meningiomas Reveals RB1 Signaling as a Novel Mediator and Biomarker by Parada, Carolina A, Osbun, Joshua W, Busald, Tina, Karasozen, Yigit, Kaur, Sumanpreet, Shi, Min, Barber, Jason, Adidharma, Widya, Cimino, Patrick J, Pan, Catherine, Gonzalez-Cuyar, Luis F, Rostomily, Robert, Born, Donald E, Zhang, Jing, Ferreira, Jr, Manuel

“…Most World Health Organization (WHO) grade I meningiomas carry a favorable prognosis. Some become clinically aggressive with recurrence, invasion, and…”
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A Clinical PET Imaging Tracer ([ 18 F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma by Beinat, Corinne, Patel, Chirag B, Haywood, Tom, Murty, Surya, Naya, Lewis, Castillo, Jessa B, Reyes, Samantha T, Phillips, Megan, Buccino, Pablo, Shen, Bin, Park, Jun Hyung, Koran, Mary Ellen I, Alam, Israt S, James, Michelle L, Holley, Dawn, Halbert, Kim, Gandhi, Harsh, He, Joy Q, Granucci, Monica, Johnson, Eli, Liu, Daniel Dan, Uchida, Nobuko, Sinha, Rahul, Chu, Pauline, Born, Donald E, Warnock, Geoffrey I, Weissman, Irving, Hayden-Gephart, Melanie, Khalighi, Mehdi, Massoud, Tarik F, Iagaru, Andrei, Davidzon, Guido, Thomas, Reena, Nagpal, Seema, Recht, Lawrence D, Gambhir, Sanjiv Sam

“…Pyruvate kinase M2 (PKM2) catalyzes the final step in glycolysis, a key process of cancer metabolism. PKM2 is preferentially expressed by glioblastoma (GBM)…”
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Periostin is a novel therapeutic target that predicts and regulates glioma malignancy by Mikheev, Andrei M, Mikheeva, Svetlana A, Trister, Andrew D, Tokita, Mari J, Emerson, Samuel N, Parada, Carolina A, Born, Donald E, Carnemolla, Barbara, Frankel, Sam, Kim, Deok-Ho, Oxford, Rob G, Kosai, Yoshito, Tozer-Fink, Kathleen R, Manning, Thomas C, Silber, John R, Rostomily, Robert C

“…Periostin is a secreted matricellular protein critical for epithelial-mesenchymal transition and carcinoma metastasis. In glioblastoma, it is highly…”
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Contractility and kinetics of human fetal and human adult skeletal muscle by Racca, Alice W., Beck, Anita E., Rao, Vijay S., Flint, Galina V., Lundy, Scott D., Born, Donald E., Bamshad, Michael J., Regnier, Michael

“…Key points •  The contractile properties of human fetal skeletal muscle are unknown. •  Reductionist approaches such as isolated myofibril and isolated…”
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Clinical Utility of GlioSeq Next-Generation Sequencing Test in Pediatric and Young Adult Patients With Brain Tumors by Roy, Somak, Agnihotri, Sameer, El Hallani, Soufiane, Ernst, Wayne L, Wald, Abigail I, Santana dos Santos, Lucas, Hamilton, Ronald L, Horbinski, Craig M, Wadhwani, Nitin R, Born, Donald E, Pollack, Ian F, Nikiforov, Yuri E, Nikiforova, Marina N

“…Brain tumors are the leading cause of death in children. Establishing an accurate diagnosis and therapy is critical for patient management. This study…”
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Comparative Proteomic Profiling Using Two-Dimensional Gel Electrophoresis and Identification via LC-MS/MS Reveals Novel Protein Biomarkers to Identify Aggressive Subtypes of WHO Grade I Meningioma by Osbun, Joshua W., Tatman, Philip D., Kaur, Sumanpreet, Parada, Carolina, Busald, Tina, Gonzalez-Cuyar, Luis, Shi, Min, Born, Donald E., Zhang, Jing, Ferreira, Manuel

“…Abstract Background  Meningomas represent the most common primary intracranial tumor. The majority are benign World Health Organization (WHO) Grade I lesions,…”
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