Search Results - "Bormann, Nicole"
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Different Achilles Tendon Pathologies Show Distinct Histological and Molecular Characteristics
Published in International journal of molecular sciences (30-01-2018)“…Reasons for the development of chronic tendon pathologies are still under debate and more basic knowledge is needed about the different diseases. The aim of…”
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Antibiotic-loaded amphora-shaped pores on a titanium implant surface enhance osteointegration and prevent infections
Published in Bioactive materials (01-08-2021)“…Artificial prostheses for joint replacement are indispensable in orthopedic surgery. Unfortunately, the implanted surface is attractive to not only host cells…”
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Histological and molecular features of the subacromial bursa of rotator cuff tears compared to non-tendon defects: a pilot study
Published in BMC musculoskeletal disorders (14-10-2021)“…Abstract Background The role of the subacromial bursa in the development or healing of shoulder pathologies is unclear. Due to this limited knowledge, we aimed…”
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Burst Release of Antibiotics Combined with Long-Term Release of Silver Targeting Implant-Associated Infections: Design, Characterization and in vitro Evaluation of Novel Implant Hybrid Surface
Published in Materials (21-11-2019)“…Implant-associated infections represent a serious risk in human medicine and can lead to complications, revisions and in worst cases, amputations. To target…”
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Impact of Gentamicin-Loaded Bone Graft on Defect Healing in a Sheep Model
Published in Materials (04-04-2019)“…Infections of bone are severe complications, and an optimization of grafting material with antimicrobial drugs might be useful for prevention and treatment…”
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Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved?
Published in Cells (Basel, Switzerland) (20-12-2023)“…So far, tendon regeneration has mainly been analyzed independent from its adjacent tissues. However, the subacromial bursa in particular appears to influence…”
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Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling
Published in Cells (Basel, Switzerland) (18-10-2019)“…The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture…”
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Analysis of the Ability of Different Allografts to Act as Carrier Grafts for Local Drug Delivery
Published in Journal of functional biomaterials (01-06-2023)“…Bone defects and infections pose significant challenges for treatment, requiring a comprehensive approach for prevention and treatment. Thus, this study sought…”
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Bursa-Derived Cells Show a Distinct Mechano-Response to Physiological and Pathological Loading in vitro
Published in Frontiers in cell and developmental biology (31-05-2021)“…The mechano-response of highly loaded tissues such as bones or tendons is well investigated, but knowledge regarding the mechano-responsiveness of adjacent…”
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Slight Changes in the Mechanical Stimulation Affects Osteoblast- and Osteoclast-Like Cells in Co-Culture
Published in Transfusion medicine and hemotherapy (01-01-2013)“…SummaryBackground: Osteoblast- and osteoclast-like cells are responsible for coordinated bone maintenance, illustrated by a balanced formation and resorption…”
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Sequential release kinetics of two (gentamicin and BMP-2) or three (gentamicin, IGF-I and BMP-2) substances from a one-component polymeric coating on implants
Published in Journal of controlled release (30-11-2011)“…The local application of antibiotics in combination with timely controlled growth factor delivery might be beneficial for the prevention of infections and to…”
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Assessment of Bones Deficient in Fibrillin-1 Microfibrils Reveals Pronounced Sex Differences
Published in International journal of molecular sciences (01-12-2019)“…Defects in the extracellular matrix protein fibrillin-1 that perturb transforming growth factor beta (TGFβ) bioavailability lead to Marfan syndrome (MFS). MFS…”
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Testing of antibiotic releasing implant coatings to fight bacteria in combat-associated osteomyelitis – an in-vitro study
Published in International orthopaedics (01-05-2016)“…Purpose Surgical procedures to prevent osteomyelitis after trauma can be supported by local application of antibiotics. This in-vitro study investigated the…”
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