Search Results - "Borlat, Irene"

Arrestin Recruitment to C-C Chemokine Receptor 5: Potent C-C Chemokine Ligand 5 Analogs Reveal Differences in Dependence on Receptor Phosphorylation and Isoform-Specific Recruitment Bias by Martins, Elsa, Brodier, Hellena, Rossitto-Borlat, Irène, Ilgaz, Ilke, Villard, Mélanie, Hartley, Oliver

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Highly potent, fully recombinant anti-HIV chemokines: Reengineering a low-cost microbicide by Gaertner, Hubert, Cerini, Fabrice, Escola, Jean-Michel, Kuenzi, Gabriel, Melotti, Astrid, Offord, Robin, Rossitto-Borlat, Irène, Nedellec, Rebecca, Salkowitz, Janelle, Gorochov, Guy, Mosier, Donald, Hartley, Oliver

“…New prevention strategies for use in developing countries are urgently needed to curb the worldwide HIV/AIDS epidemic. The N-terminally modified chemokine…”
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Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5 by Bönsch, Claudia, Munteanu, Mihaela, Rossitto-Borlat, Irène, Fürstenberg, Alexandre, Hartley, Oliver

“…G protein-coupled receptors (GPCRs) are desensitized and internalized following activation. They are then subjected to post-endocytic sorting (degradation,…”
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Generating Chemokine Analogs with Enhanced Pharmacological Properties Using Phage Display by Dorgham, Karim, Cerini, Fabrice, Gaertner, Hubert, Melotti, Astrid, Rossitto-Borlat, Irène, Gorochov, Guy, Hartley, Oliver

“…Phage display technology, which allows extremely rare ligands to be selected from libraries of variants according to user-defined selection criteria, has made…”
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Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1 by Yuzugulen, Jale, Douthwaite, Julie A., Wood, Elizabeth G., Villar, Inmaculada C., Patel, Nimesh S. A., Jegard, James, Gaertner, Hubert, Rossitto-Borlat, Irène, Rose, Keith, Hartley, Oliver, Cutillas, Pedro R., Ahluwalia, Amrita, Corder, Roger

“…Endothelin-1 (ET-1) is involved in the pathogenesis of cardiac and renal diseases, and in the progression of tumour growth in cancer, but current diagnosis and…”
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C2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and human by Bontems, Franck, Fish, Richard J, Borlat, Irene, Lembo, Frédérique, Chocu, Sophie, Chalmel, Frédéric, Borg, Jean-Paul, Pineau, Charles, Neerman-Arbez, Marguerite, Bairoch, Amos, Lane, Lydie

“…Vertebrate genomes contain around 20,000 protein-encoding genes, of which a large fraction is still not associated with specific functions. A major task in…”
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Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments by Fagète, Séverine, Botas-Perez, Ledicia, Rossito-Borlat, Irène, Adea, Kenneth, Gueneau, Franck, Ravn, Ulla, Rousseau, François, Kosco-Vilbois, Marie, Fischer, Nicolas, Hartley, Oliver

“…ABSTRACT Antibody phage display technology has supported the emergence of numerous therapeutic antibodies. The development of bispecific antibodies, a…”
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Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1β/CCL4 by Gaertner, Hubert, Lebeau, Olivier, Borlat, Irène, Cerini, Fabrice, Dufour, Brigitte, Kuenzi, Gabriel, Melotti, Astrid, Fish, Richard J., Offord, Robin, Springael, Jean-Yves, Parmentier, Marc, Hartley, Oliver

“…The HIV coreceptor CCR5 is a validated target for both the prevention and therapy of HIV infection. PSC-RANTES, an N-terminally modified analogue of one of the…”
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Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene by Yuzugulen, Jale, Wood, Elizabeth G., Villar, Inmaculada C., Douthwaite, Julie A., Patel, Nimesh S.A./INS, Jegard, James, Montoya, Alexander, Cutillas, Pedro, Gaertner, Hubert, Rossitto-Borlat, Irene, Rose, Keith, Hartley, Oliver, Ahluwalia, Amrita, Corder, Roger

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Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5: e0125396 by Bonsch, Claudia, Munteanu, Mihaela, Rossitto-Borlat, Irene, Fuerstenberg, Alexandre, Hartley, Oliver

“…G protein-coupled receptors (GPCRs) are desensitized and internalized following activation. They are then subjected to post-endocytic sorting (degradation,…”
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C2orf62 and TTC17 Are Involved in Actin Organization and Ciliogenesis in Zebrafish and Human: e86476 by Bontems, Franck, Fish, Richard J, Borlat, Irene, Lembo, Frederique, Chocu, Sophie, Chalmel, Frederic, Borg, Jean-Paul, Pineau, Charles, Neerman-Arbez, Marguerite, Bairoch, Amos

“…Vertebrate genomes contain around 20,000 protein-encoding genes, of which a large fraction is still not associated with specific functions. A major task in…”
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RB110 and RB157 antibodies recognize by ELISA specific phosphorylation patterns on CCR5 C-terminal peptides by Paolini-Bertrand, Marianne, Rossitto-Borlat, Irène, Martins, Elsa, Hartley, Oliver

“…Recombinant antibodies RB110 and RB157 can be used in ELISA assays to specifically detect human CCR5 phosphorylated at serines 336/337 and at serine 349,…”
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Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 /CCL4 by Gaertner, H., Lebeau, O., Borlat, I., Cerini, F., Dufour, B., Kuenzi, G., Melotti, A., Fish, R. J., Offord, R., Springael, J.-Y., Parmentier, M., Hartley, O.

“…The HIV coreceptor CCR5 is a validated target for both the prevention and therapy of HIV infection. PSC-RANTES, an N-terminally modified analogue of one of the…”
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