Search Results - "Borisy, Gary"

Biogeography of the Oral Microbiome: The Site-Specialist Hypothesis by Mark Welch, Jessica L, Dewhirst, Floyd E, Borisy, Gary G

“…Microbial communities are complex and dynamic, composed of hundreds of taxa interacting across multiple spatial scales. Advances in sequencing and imaging…”
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Multiplexed Spectral Imaging of 120 Different Fluorescent Labels by Valm, Alex M, Oldenbourg, Rudolf, Borisy, Gary G

“…The number of fluorescent labels that can unambiguously be distinguished in a single image when acquired through band pass filters is severely limited by the…”
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Biogeography of a human oral microbiome at the micron scale by Welch, Jessica L. Mark, Rossetti, Blair J., Rieken, Christopher W., Dewhirst, Floyd E., Borisy, Gary G.

“…The spatial organization of complex natural microbiomes is critical to understanding the interactions of the individual taxa that comprise a community…”
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Oral Microbiome Geography: Micron-Scale Habitat and Niche by Mark Welch, Jessica L, Ramírez-Puebla, S Tabita, Borisy, Gary G

“…The mouth presents a multiplicity of local environments in communication with one another via saliva. The spatial organization of microbes within the mouth is…”
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Spatial Ecology of the Human Tongue Dorsum Microbiome by Wilbert, Steven A., Mark Welch, Jessica L., Borisy, Gary G.

“…A fundamental question in microbial ecology is how microbes are spatially organized with respect to each other and their host. A test bed for examining this…”
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Spatial organization of a model 15-member human gut microbiota established in gnotobiotic mice by Welch, Jessica L. Mark, Hasegawa, Yuko, McNulty, Nathan P., Gordon, Jeffrey I., Borisy, Gary G.

“…Knowledge of the spatial organization of the gut microbiota is important for understanding the physical and molecular interactions among its members. These…”
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Spatial scale in analysis of the dental plaque microbiome by Borisy, Gary G., Valm, Alex M., Darveau, Richard, Curtis, Mike

“…Ecologists have long recognized the importance of spatial scale in understanding structure‐function relationships among communities of organisms within their…”
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Oligotyping analysis of the human oral microbiome by Eren, A Murat, Borisy, Gary G, Huse, Susan M, Mark Welch, Jessica L

“…The Human Microbiome Project provided a census of bacterial populations in healthy individuals, but an understanding of the biomedical significance of this…”
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Microbiota organization is a distinct feature of proximal colorectal cancers by Dejea, Christine M., Wick, Elizabeth C., Hechenbleikner, Elizabeth M., White, James R., Welch, Jessica L. Mark, Rossetti, Blair J., Peterson, Scott N., Snesrud, Erik C., Borisy, Gary G., Lazarev, Mark, Stein, Ellen, Vadivelu, Jamuna, Roslani, April C., Malik, Ausuma A., Wanyiri, Jane W., Goh, Khean L., Thevambiga, Iyadorai, Fu, Kai, Wan, Fengyi, Llosa, Nicolas, Housseau, Franck, Romans, Katharine, Wu, XinQun, McAllister, Florencia M., Wu, Shaoguang, Vogelstein, Bert, Kinzler, Kenneth W., Pardoll, Drew M., Sears, Cynthia L.

“…Environmental factors clearly affect colorectal cancer (CRC) incidence, but the mechanisms through which these factors function are unknown. One prime…”
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Metapangenomics of the oral microbiome provides insights into habitat adaptation and cultivar diversity by Utter, Daniel R, Borisy, Gary G, Eren, A Murat, Cavanaugh, Colleen M, Mark Welch, Jessica L

“…The increasing availability of microbial genomes and environmental shotgun metagenomes provides unprecedented access to the genomic differences within related…”
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Lévy-like movement patterns of metastatic cancer cells revealed in microfabricated systems and implicated in vivo by Huda, Sabil, Weigelin, Bettina, Wolf, Katarina, Tretiakov, Konstantin V., Polev, Konstantin, Wilk, Gary, Iwasa, Masatomo, Emami, Fateme S., Narojczyk, Jakub W., Banaszak, Michal, Soh, Siowling, Pilans, Didzis, Vahid, Amir, Makurath, Monika, Friedl, Peter, Borisy, Gary G., Kandere-Grzybowska, Kristiana, Grzybowski, Bartosz A.

“…Metastatic cancer cells differ from their non-metastatic counterparts not only in terms of molecular composition and genetics, but also by the very strategy…”
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Tip extension and simultaneous multiple fission in a filamentous bacterium by Chimileski, Scott, Borisy, Gary G, Dewhirst, Floyd E, Mark Welch, Jessica L

“…Organisms display an immense variety of shapes, sizes, and reproductive strategies. At microscopic scales, bacterial cell morphology and growth dynamics are…”
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Cellular Motility Driven by Assembly and Disassembly of Actin Filaments by Pollard, Thomas D, Borisy, Gary G

“…Motile cells extend a leading edge by assembling a branched network of actin filaments that produces physical force as the polymers grow beneath the plasma…”
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Preservation of three-dimensional spatial structure in the gut microbiome by Hasegawa, Yuko, Mark Welch, Jessica L, Rossetti, Blair J, Borisy, Gary G

“…Preservation of three-dimensional structure in the gut is necessary in order to analyze the spatial organization of the gut microbiota and gut luminal…”
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Role of fascin in filopodial protrusion by Vignjevic, Danijela, Kojima, Shin-ichiro, Aratyn, Yvonne, Danciu, Oana, Svitkina, Tatyana, Borisy, Gary G

“…In this study, the mechanisms of actin-bundling in filopodia were examined. Analysis of cellular localization of known actin cross-linking proteins in mouse…”
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Systems-level analysis of microbial community organization through combinatorial labeling and spectral imaging by Valm, Alex M, Welch, Jessica L. Mark, Rieken, Christopher W, Hasegawa, Yuko, Sogin, Mitchell L, Oldenbourg, Rudolf, Dewhirst, Floyd E, Borisy, Gary G

“…Microbes in nature frequently function as members of complex multitaxon communities, but the structural organization of these communities at the micrometer…”
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Genome-Centric Dynamics Shape the Diversity of Oral Bacterial Populations by Utter, Daniel R, Cavanaugh, Colleen M, Borisy, Gary G

“…Two major viewpoints have been put forward for how microbial populations change, differing in whether adaptation is driven principally by gene-centric or…”
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Systematic evasion of the restriction-modification barrier in bacteria by Johnston, Christopher D., Cotton, Sean L., Rittling, Susan R., Starr, Jacqueline R., Borisy, Gary G., Dewhirst, Floyd E., Lemon, Katherine P.

“…Bacteria that are recalcitrant to genetic manipulation using modern in vitro techniques are termed genetically intractable. Genetic intractability is a…”
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Individuality, Stability, and Variability of the Plaque Microbiome by Utter, Daniel R, Mark Welch, Jessica L, Borisy, Gary G

“…Dental plaque is a bacterial biofilm composed of a characteristic set of organisms. Relatively little information from cultivation-independent, high-throughput…”
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Corncob structures in dental plaque reveal microhabitat taxon specificity by Morillo-Lopez, Viviana, Sjaarda, Alexandra, Islam, Imon, Borisy, Gary G, Mark Welch, Jessica L

“…The human mouth is a natural laboratory for studying how bacterial communities differ across habitats. Different bacteria colonize different surfaces in the…”
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