Search Results - "Borisova, Ksenia L."
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Dimeric (Poly)Hydroxynaphthazarins, Metabolites of Echinoderms and Lichens: The History of the Synthesis and Structure Elucidation
Published in Marine drugs (19-07-2023)“…This review provides information on the synthesis and revision of the structures of natural dimeric (poly)hydroxynaphthazarins, metabolites of echinoderms and…”
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Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer
Published in Marine drugs (11-05-2020)“…The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred…”
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Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
Published in Pharmaceuticals (Basel, Switzerland) (22-09-2021)“…Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here,…”
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Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
Published in Cancers (30-10-2019)“…Treatment of castration-resistant prostate cancer (CRPC) remains challenging due to the development of drug resistance. The Warburg effect describes the…”
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Quinone–carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: Synthesis and determination of in vitro activity
Published in European journal of medicinal chemistry (22-04-2014)“…We have found that 2-methoxy-1,4-naphthoquinones easily react with primary alcohols to produce the corresponding 2-alkoxyderivatives. Using this reaction, we…”
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Concerning the structure of islandoquinone isolated from the lichen Cetraria islandica
Published in Natural product communications (01-06-2014)“…An investigation of the oxidative coupling products of some substituted hydroxynaphthazarins led to a revision of the proposed structure of islandoquinone,…”
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A simple synthesis of natural spinazarins and their analogues
Published in Mendeleev communications (01-03-2023)“…[Display omitted] A short simple synthesis of spinazarins (2,3-dihydroxy-naphthazarins or 2,3,5,8-tetrahydroxy-1,4-naphtho-quinones) from available…”
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Unexpected conversion of echinochrome to brominated spinochrome D. Synthesis of 2-amino-3,6,7-trihydroxynaphthazarin produced by the sea urchins Strongylocentrotus nudus and Psammechinus miliaris
Published in Tetrahedron letters (17-02-2016)“…[Display omitted] Two approaches to the total synthesis of 2-amino-3,6,7-trihydroxynaphthazarin, a metabolite of the sea urchins Strongylocentrotus nudus and…”
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