Search Results - "Borin, Lorenza"

Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission by Wei, Andrew H, Döhner, Hartmut, Pocock, Christopher, Montesinos, Pau, Afanasyev, Boris, Dombret, Hervé, Ravandi, Farhad, Sayar, Hamid, Jang, Jun-Ho, Porkka, Kimmo, Selleslag, Dominik, Sandhu, Irwindeep, Turgut, Mehmet, Giai, Valentina, Ofran, Yishai, Kizil Çakar, Merih, Botelho de Sousa, Aida, Rybka, Justyna, Frairia, Chiara, Borin, Lorenza, Beltrami, Germana, Čermák, Jaroslav, Ossenkoppele, Gert J, La Torre, Ignazia, Skikne, Barry, Kumar, Keshava, Dong, Qian, Beach, C.L, Roboz, Gail J

“…Older patients with acute myeloid leukemia were treated with intensive chemotherapy and then randomly assigned to receive placebo or oral azacitidine (CC-486)…”
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Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes by Bersanelli, Matteo, Travaglino, Erica, Meggendorfer, Manja, Matteuzzi, Tommaso, Sala, Claudia, Mosca, Ettore, Chiereghin, Chiara, Di Nanni, Noemi, Gnocchi, Matteo, Zampini, Matteo, Rossi, Marianna, Maggioni, Giulia, Termanini, Alberto, Angelucci, Emanuele, Bernardi, Massimo, Borin, Lorenza, Bruno, Benedetto, Bonifazi, Francesca, Santini, Valeria, Bacigalupo, Andrea, Voso, Maria Teresa, Oliva, Esther, Riva, Marta, Ubezio, Marta, Morabito, Lucio, Campagna, Alessia, Saitta, Claudia, Savevski, Victor, Giampieri, Enrico, Remondini, Daniel, Passamonti, Francesco, Ciceri, Fabio, Bolli, Niccolò, Rambaldi, Alessandro, Kern, Wolfgang, Kordasti, Shahram, Sole, Francesc, Palomo, Laura, Sanz, Guillermo, Santoro, Armando, Platzbecker, Uwe, Fenaux, Pierre, Milanesi, Luciano, Haferlach, Torsten, Castellani, Gastone, Della Porta, Matteo G

“…Recurrently mutated genes and chromosomal abnormalities have been identified in myelodysplastic syndromes (MDS). We aim to integrate these genomic features…”
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Predicting the probability of Gaucher disease in subjects with splenomegaly and thrombocytopenia by Motta, Irene, Consonni, Dario, Stroppiano, Marina, Benedetto, Christian, Cassinerio, Elena, Tappino, Barbara, Ranalli, Paola, Borin, Lorenza, Facchini, Luca, Patriarca, Andrea, Barcellini, Wilma, Lanza, Federica, Filocamo, Mirella, Cappellini, Maria Domenica

“…Hematologists are frequently involved in the diagnostic pathway of Gaucher disease type 1 (GD1) patients since they present several hematological signs…”
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Feasibility and effectiveness of the prolonged use of eltrombopag in addition to immunosuppression in patients with acquired aplastic anemia: a single-center real-life experience by Carpenedo, Monica, Zappaterra, Arianna, Del Castello, Lorenzo, Ferrari, Beatrice, Cotilli, Giulia, Bernasconi, Davide Paolo, Pezzatti, Sara, Sacco, Filippo, Borin, Lorenza, Carrer, Andrea, Verga, Luisa, Brioschi, Filippo

“…Acquired Aplastic Anemia (AAA) is a rare disease involving primary bone marrow failure with consequent pancytopenia. The addition of the synthetic…”
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Nilotinib interferes with cell cycle, ABC transporters and JAK-STAT signaling pathway in CD34+/lin- cells of patients with chronic phase chronic myeloid leukemia after 12 months of treatment by Trojani, Alessandra, Pungolino, Ester, Dal Molin, Alessandra, Lodola, Milena, Rossi, Giuseppe, D'Adda, Mariella, Perego, Alessandra, Elena, Chiara, Turrini, Mauro, Borin, Lorenza, Bucelli, Cristina, Malato, Simona, Carraro, Maria Cristina, Spina, Francesco, Latargia, Maria Luisa, Artale, Salvatore, Spedini, Pierangelo, Anghilieri, Michela, Di Camillo, Barbara, Baruzzo, Giacomo, De Canal, Gabriella, Iurlo, Alessandra, Morra, Enrica, Cairoli, Roberto

“…Chronic myeloid leukemia (CML) is characterized by the constitutive tyrosine kinase activity of the oncoprotein BCR-ABL1 in myeloid progenitor cells that…”
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Valproic Acid at Therapeutic Plasma Levels May Increase 5-Azacytidine Efficacy in Higher Risk Myelodysplastic Syndromes by VOSO, Maria Teresa, SANTINI, Valeria, BUCCISANO, Francesco, GOBBI, Marco, BORIN, Lorenza, DI TUCCI, Anna, ZINI, Gina, PETTI, Maria Concetta, MARTINELLI, Giovanni, FABIANI, Emiliano, FAZI, Paola, VIGNETTI, Marco, FINELLI, Carlo, PICIOCCHI, Alfonso, LISO, Vincenzo, AMADORI, Sergio, LEONE, Giuseppe, MUSTO, Pellegrino, POGLIANI, Enrico, ANGELUCCI, Emanuele, FIORITONI, Giuseppe, ALIMENA, Giuliana, MAURILLO, Luca, CORTELEZZI, Agostino

“…Purpose: Epigenetic changes play a role and cooperate with genetic alterations in the pathogenesis of myelodysplastic syndromes (MDS). We conducted a phase II…”
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Danazol Treatment for Thrombocytopenia in Myelodysplastic Syndromes: Can an “Old‐fashioned” Drug be Effective? by Riva, Marta, Bosi, Alessandro, Rizzo, Lorenzo, Mazzon, Federico, Ferrari, Silvia, Lussana, Federico, Borin, Lorenza, Castelli, Andrea, Cairoli, Roberto, Barcellini, Wilma, Molteni, Alfredo, Fattizzo, Bruno

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Non transferrin bound iron (NTBI) in acute leukemias throughout conventional intensive chemotherapy: Kinetics of its appearance and potential predictive role in infectious complications by Belotti, Angelo, Duca, Lorena, Borin, Lorenza, Realini, Silvia, Renso, Rossella, Parma, Matteo, Pioltelli, Pietro, Pogliani, Enrico, Cappellini, Maria Domenica

“…Highlights • Intensive chemotherapy causes the appearance of NTBI, independently from transfusions. • Formation of NTBI is a consequence of chemotherapy…”
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PB1879: EFFICACY AND SAFETY OF CPX‐351 COMPARED TO STANDARD OF CARE CHEMOTHERAPY IN A REAL‐LIFE SETTING: SUPPORTING PREVIOUS EVIDENCE AND FACING NEW CHALLENGES by Manghisi, Beatrice, Alberti, Sara, Ripamonti, Alessia, Perfetti, Paola, Borin, Lorenza Maria, Fumagalli, Monica, Passerini, Carlo Gambacorti

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Humoral and cellular immune response in patients with hematological disorders after two doses of BNT162b2 mRNA COVID‐19 vaccine: A single‐center prospective observational study (NCT05074706) by Bossi, Elisa, Aroldi, Andrea, Borin, Lorenza Maria, Verga, Luisa, Fontana, Diletta, Cocito, Federica, Manghisi, Beatrice, Rindone, Giovanni, Cavalca, Fabrizio, Ripamonti, Alessia, Raggi, Monica, Malandrin, Sergio Maria Ivano, Cavallero, Annalisa, Antolini, Laura, Bonardi, Diego, Piazza, Rocco Giovanni, Gambacorti‐Passerini, Carlo

“…Hematological patients at higher risk of severe COVID‐19 were excluded from the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccine trials. In…”
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A CASE OF ATYPICAL PROLONGED HEMATOLOGIC TOXICITY WITH AZACITIDINE IN CHRONIC MYELOMONOCYTIC LEUKEMIA (CMML), REVIEW OF LITERATURE AND A PROPOSAL OF MANAGEMENT by Elli, Elena, Cecchetti, Caterina, Belotti, Angelo, Borin, Lorenza

“…Hypomethylating drugs are useful and approved in the management of myelodysplastic syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML). However, phase 2…”
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Iron toxicity – Its effect on the bone marrow by Isidori, Alessandro, Borin, Lorenza, Elli, Elena, Latagliata, Roberto, Martino, Bruno, Palumbo, Giuseppe, Pilo, Federica, Loscocco, Federica, Visani, Giuseppe, Cianciulli, Paolo

“…Excess iron can be extremely toxic for the body and may cause organ damage in the absence of iron chelation therapy. Preclinical studies on the role of free…”
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Real-World Validation of Molecular International Prognostic Scoring System for Myelodysplastic Syndromes by Sauta, Elisabetta, Robin, Marie, Bersanelli, Matteo, Travaglino, Erica, Meggendorfer, Manja, Zhao, Lin-Pierre, Caballero Berrocal, Juan Carlos, Sala, Claudia, Maggioni, Giulia, Bernardi, Massimo, Di Grazia, Carmen, Vago, Luca, Rivoli, Giulia, Borin, Lorenza, D'Amico, Saverio, Tentori, Cristina Astrid, Ubezio, Marta, Campagna, Alessia, Russo, Antonio, Mannina, Daniele, Lanino, Luca, Chiusolo, Patrizia, Giaccone, Luisa, Voso, Maria Teresa, Riva, Marta, Oliva, Esther Natalie, Zampini, Matteo, Riva, Elena, Nibourel, Olivier, Bicchieri, Marilena, Bolli, Niccolo', Rambaldi, Alessandro, Passamonti, Francesco, Savevski, Victor, Santoro, Armando, Germing, Ulrich, Kordasti, Shahram, Santini, Valeria, Diez-Campelo, Maria, Sanz, Guillermo, Sole, Francesc, Kern, Wolfgang, Platzbecker, Uwe, Ades, Lionel, Fenaux, Pierre, Haferlach, Torsten, Castellani, Gastone, Della Porta, Matteo Giovanni

“…Myelodysplastic syndromes (MDS) are heterogeneous myeloid neoplasms in which a risk-adapted treatment strategy is needed. Recently, a new clinical-molecular…”
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Efficacy and Safety of Danazol in Patients with Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms: A Multicenter Observational Study by Bosi, Alessandro, Fattizzo, Bruno, Rizzo, Lorenzo, Ferrari, Silvia, Lussana, Federico, Borin, Lorenza Maria, Castelli, Andrea, Bianchi, Paola, Barcellini, Wilma, Cairoli, Roberto, Molteni, Alfredo, Riva, Marta

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High-Risk Population Screening for Gaucher Disease: Final Results and Key Learnings from an Italian Multicenter Observational Study by Motta, Irene, Benedetto, Christian, Stroppiano, Marina, Cassinerio, Elena, Consonni, Dario, Borin, Lorenza, Ranalli, Paola, Barcellini, Wilma, Cappellini, Maria Domenica

“…▪ Background:Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder due to the deficiency of beta-glucosidase enzyme. Its prevalence in the…”
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Communicating the diagnosis of a hematological neoplastic disease to patients' minor children: a multicenter prospective study by Manghisi, Beatrice, Borin, Lorenza, Monaco, Maria Rosaria, Sacco, Gaia Giulia Angela, Antolini, Laura, Mantegazza, Raffaele, Barichello, Monica, Mazza, Umberto, Zappasodi, Patrizia, Onida, Francesco, Arcaini, Luca, Cairoli, Roberto, Gambacorti Passerini, Carlo

“…When a hematological malignancy is diagnosed, the whole family carries the burden of the disease; parents often try to protect minor children from suffering by…”
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Retaining Parental Role Despite the Presence of Hematological Neoplastic Diseases: The Emanuela Project and the Role of the Hematologist by Manghisi, Beatrice, Borin, Lorenza Maria, Monaco, maria Rosaria, Mantegazza, Raffaele, Gambacorti-Passerini, Carlo

“…Introduction The diagnosis of a hematological neoplastic disease (HND) bears a great impact on the patient family, which suffers abrupt changes in living…”
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Validation of a new NGS-based myeloid panel in acute myeloid leukemia: A single-center experience by Steidl, Carolina, Aroldi, Andrea, Mologni, Luca, Crespiatico, Ilaria, Fontana, Diletta, Mastini, Cristina, Fumagalli, Monica, Perfetti, Paola, Borin, Lorenza, Valentini, Claudia, Piazza, Rocco, Gambacorti-Passerini, Carlo

“…Acute myeloid leukemia (AML) identifies a heterogeneous group of clonal disorders, both clinically and genetically. A large number of mutations have been…”
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Patient‐reported outcomes enhance the survival prediction of traditional disease risk classifications: An international study in patients with myelodysplastic syndromes by Efficace, Fabio, Cottone, Francesco, Abel, Gregory, Niscola, Pasquale, Gaidano, Gianluca, Bonnetain, Franck, Anota, Amelie, Caocci, Giovanni, Cronin, Angel, Fianchi, Luana, Breccia, Massimo, Stauder, Reinhard, Platzbecker, Uwe, Palumbo, Giuseppe A., Luppi, Mario, Invernizzi, Rosangela, Bergamaschi, Micaela, Borin, Lorenza, Di Tucci, Anna Angela, Zhang, Huiyong, Sprangers, Mirjam, Vignetti, Marco, Mandelli, Franco

“…BACKGROUND Current prognostic systems for myelodysplastic syndromes (MDS) are based on clinical, pathologic, and laboratory indicators. The objective of the…”
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Deferasirox for transfusion-dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial) by Angelucci, Emanuele, Santini, Valeria, Di Tucci, Anna Angela, Quaresmini, Giulia, Finelli, Carlo, Volpe, Antonio, Quarta, Giovanni, Rivellini, Flavia, Sanpaolo, Grazia, Cilloni, Daniela, Salvi, Flavia, Caocci, Giovanni, Molteni, Alfredo, Vallisa, Daniele, Voso, Maria Teresa, Fenu, Susanna, Borin, Lorenza, Latte, Giancarlo, Alimena, Giuliana, Storti, Sergio, Piciocchi, Alfonso, Fazi, Paola, Vignetti, Marco, Tura, Sante

“…Background In the absence of randomized, controlled trial data to support iron chelation therapy in transfusion‐dependent patients with myelodysplastic…”
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