Search Results - "Borhani, Shayan"
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Microwave induced thermally assisted solvent-based bonding of biodegradable thermoplastics: an eco-friendly rapid approach for fabrication of microfluidic devices and analyte detection
Published in Scientific reports (27-09-2022)“…There is an increasing interest in low-cost, facile and versatile thermoplastic bonding for microfluidic applications that can be easily transitioned from…”
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An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics
Published in New biotechnology (25-09-2023)“…This study describes the cell-free biomanufacturing of a broad-spectrum antiviral protein, griffithsin (GRFT) such that it can be produced in microgram…”
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Point-of-care production of therapeutic proteins of good-manufacturing-practice quality
Published in Nature biomedical engineering (01-09-2018)“…Manufacturing technologies for biologics rely on large, centralized, good-manufacturing-practice (GMP) production facilities and on a cumbersome…”
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Alternative Approaches to Insulin Manufacturing Using Cell-Free Systems
Published 01-01-2023“…The modular nature of cell-free protein synthesis (CFPS) has resulted in a paradigm shift in the way scientists can design, discover, and manufacture…”
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Dissertation -
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Modeling transcriptional factor cross-talk to understand parabolic kinetics, bimodal gene expression and retroactivity in biosensor design
Published in Biochemical engineering journal (15-04-2019)“…•ODE-based kinetic model formulated to simulate transcriptional factor (TF) cross-talk.•TF repression, protein degradation, and cell growth dilution were…”
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Improving the recombinant human erythropoietin glycosylation using microsome supplementation in CHO cell‐free system
Published in Biotechnology and bioengineering (01-05-2018)“…Cell‐Free Protein Synthesis (CFPS) offers many advantages for the production of recombinant therapeutic proteins using the CHO cell‐free system. However, many…”
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Manufacturing biological medicines on demand: Safety and efficacy of granulocyte colony‐stimulating factor in a mouse model of total body irradiation
Published in Biotechnology progress (01-05-2020)“…Protein therapeutics, also known as biologics, are currently manufactured at centralized facilities according to rigorous protocols. The manufacturing process…”
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Journal Article