Search Results - "Borgono, C"

Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis by YOUSEF, G. M, BORGONO, C. A, SCORILAS, A, PONZONE, R, BIGLIA, N, ISKANDER, L, POLYMERIS, M.-E, ROAGNA, R, SISMONDI, P, DIAMANDIS, E. P

“…KLK14 (formerly known as KLK-L6) is a recently identified member of the human kallikrein gene family. This family harbours several genes aberrantly expressed…”
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Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status by FRITZSCHE, F, GANSUKH, T, STEPHAN, C, DIETEL, M, DIAMANDIS, E. P, DAHL, E, KRISTIANSEN, G, BORGONO, C. A, BURKHARDT, M, PAHL, S, MAYORDOMO, E, WINZER, K.-J, WEICHERT, W, DENKERT, C, JUNG, K

“…Human kallikrein 14 (KLK14) is a steroid hormone-regulated member of the tissue kallikrein family of serine proteases, for which a prognostic and diagnostic…”
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Patterns of benzodiazepine (B) use and dependence in Canada by Borgoño, C., Busto, U.E., Sellers, E.M.

“…Clinical Pharmacology & Therapeutics (1999) 65, 142–142; doi:…”
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Hypersensitivity to acetaldehyde-protein adducts by Israel, Y, MacDonald, A, Niemelä, O, Zamel, D, Shami, E, Zywulko, M, Klajner, F, Borgono, C

“…Acetaldehyde, the first product in the metabolism of ethanol, is known to condense with plasma proteins, forming stable adducts. We have previously shown that…”
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In-silico Analysis of Kallikrein Gene Expression in Pancreatic and Colon Cancers by YOUSEF, George M, BORGONO, Carla A, POPALIS, Cynthia, YACOUB, George M, POLYMERIS, Mary-Ellen, SOOSAIPILLAI, Antoninus, DIAMANDIS, Eleftherios P

“…Human kallikreins are a cluster of 15 serine protease genes located in the chromosomal band 19q13.4, a non-randomly rearranged region in many solid tumors,…”
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Human kallikrein 5: A potential novel serum biomarker for breast and ovarian cancer by YOUSEF, George M, POLYMERIS, Mary-Ellen, SCHMITT, Manfred, DIAMANDIS, Eleftherios P, GRASS, Linda, SOOSAIPILLAI, Antoninus, CHAN, Pak-Cheung, SCORILAS, Andreas, BORGONO, Carla, HARBECK, Nadia, SCHMALFELDT, Barbara, DORN, Julia

“…The kallikrein family is a group of 15 serine protease genes clustered on chromosome 19q13.4. Human kallikrein (hK) gene 5 (KLK5) is a member of this family…”
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A survey of alternative transcripts of human tissue kallikrein genes by Kurlender, Lisa, Borgono, Carla, Michael, Iacovos P., Obiezu, Christina, Elliott, Marc B., Yousef, George M., Diamandis, Eleftherios P.

“…Alternative splicing is prevalent within the human tissue kallikrein gene locus. Aside from being the most important source of protein diversity in eukaryotes,…”
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The emerging roles of human tissue kallikreins in cancer by Diamandis, Eleftherios P, Borgoño, Carla A

“…Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of protease genes in the human genome, are secreted serine proteases with…”
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Prognostic Value of the Human Kallikrein Gene 15 Expression in Ovarian Cancer by YOUSEF, George M, SCORILAS, Andreas, KATSAROS, Dionyssios, FRACCHIOLI, Stefano, ISKANDER, Lisa, BORGONO, Carla, RIGAULT DE LA LONGRAIS, Irene A, PUOPOLO, Manuela, MASSOBRIO, Marco, DIAMANDIS, Eleftherios P

“…KLK15 is a newly cloned human kallikrein gene. Many kallikreins were found to be differentially expressed in ovarian cancer. Like other kallikreins, KLK15 is…”
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Human Tissue Kallikreins: Physiologic Roles and Applications in Cancer by Borgoño, Carla A, Michael, Iacovos P, Diamandis, Eleftherios P

“…Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases and are present in at least six mammalian orders. In humans, tissue…”
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Differential expression of a human kallikrein 5 (KLK5) splice variant in ovarian and prostate cancer by Kurlender, Lisa, Yousef, George M, Memari, Nader, Robb, John-Desmond, Michael, Iacovos P, Borgoño, Carla, Katsaros, Dionyssios, Stephan, Carsten, Jung, Klaus, Diamandis, Eleftherios P

“…The presence of more than one mRNA form is common among kallikrein genes. We identified an mRNA transcript of the human kallikrein gene 5 (KLK5), denoted KLK5…”
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Human kallikrein 14: A new potential biomarker for ovarian and breast cancer by BORGONO, Carla A, GRASS, Linda, SOOSAIPILLAI, Antoninus, YOUSEF, George M, PETRAKI, Constantina D, HOWARTH, David H. C, FRACCHIOLI, Stefano, KATSAROS, Dionyssios, DIAMANDIS, Eleftherios P

“…Human kallikrein gene 14 (KLK14) is a recently discovered member of the tissue kallikrein family of secreted serine proteases, which includes…”
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Human Kallikrein 8 Protein Is a Favorable Prognostic Marker in Ovarian Cancer by BORGONO, Carla A, KISHI, Tadaaki, SCORILAS, Andreas, HARBECK, Nadia, DORN, Julia, SCHMALFELDT, Barbara, SCHMITT, Manfred, DIAMANDIS, Eleftherios P

“…Human kallikrein 8 (hK8/neuropsin/ovasin; encoded by KLK8 ) is a steroid hormone–regulated secreted serine protease differentially expressed in ovarian…”
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Human Kallikrein 13 Protein in Ovarian Cancer Cytosols: A New Favorable Prognostic Marker by SCORILAS, Andreas, BORGONO, Carla A, HARBECK, Nadia, DORN, Julia, SCHMALFELDT, Barbara, SCHMITT, Manfred, DIAMANDIS, Eleftherios P

“…Human kallikrein 13 (hK13; encoded by the KLK13 gene) is a secreted serine protease expressed in endocrine tissues, including the prostate, testis, breast, and…”
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The human kallikrein protein 5 (hK5) is enzymatically active, glycosylated and forms complexes with two protease inhibitors in ovarian cancer fluids by Yousef, George M., Kapadia, Carl, Polymeris, Mary-Ellen, Borgoňo, Carla, Hutchinson, Shirley, Wasney, Gregory A., Soosaipillai, Antoninus, Diamandis, Eleftherios P.

“…The kallikrein family is a group of 15 serine protease genes clustered on chromosome 19q13.4. Binding of kallikreins to protease inhibitors is an important…”
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Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients by Diamandis, Eleftherios P., Borgoño, Carla A., Scorilas, Andreas, Harbeck, Nadia, Dorn, Julia, Schmitt, Manfred

“…Objectives: Human kallikrein 11 (hK11) is a secreted serine protease, highly expressed in hormonally regulated tissues, including the prostate and the ovary…”
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Enzymatic profiling of human kallikrein 14 using phage-display substrate technology by Felber, Loyse M, Borgoño, Carla A, Cloutier, Sylvain M, Kündig, Christoph, Kishi, Tadaaki, Ribeiro Chagas, Jair, Jichlinski, Patrice, Gygi, Christian M, Leisinger, Hans-Jürg, Diamandis, Eleftherios P, Deperthes, David

“…The human KLK14 gene is one of the newly identified serine protease genes belonging to the human kallikrein family, which contains 15 members. KLK14 , like all…”
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Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma by Borgoño, Carla A., Fracchioli, Stefano, Yousef, George M., Rigault de la Longrais, Irene A., Luo, Liu‐Ying, Soosaipillai, Antoninus, Puopolo, Manuela, Grass, Linda, Scorilas, Andreas, Diamandis, Eleftherios P., Katsaros, Dionyssios

“…Human kallikrein 11 (hK11/trypsin‐like serine protease/TLSP, encoded by the KLK11 gene) is a member of the kallikrein family of secreted serine proteases…”
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Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer by YOUSEF, George M, FRACCHIOLI, Stefano, SCORILAS, Andreas, BORGONO, Carla A, ISKANDER, Lisa, PUOPOLO, Manuela, MASSOBRIO, Marco, DIAMANDIS, Eleftherios P, KATSAROS, Dionyssios

“…To study KLK14 gene expression in endocrine-related cancers, we studied its hormonal regulation in breast and ovarian cancer cell lines. Our kinetic and…”
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Immunofluorometric quantification of human kallikrein 5 expression in ovarian cancer cytosols and its association with unfavorable patient prognosis by Diamandis, Eleftherios P, Borgoño, Carla A, Scorilas, Andreas, Yousef, George M, Harbeck, Nadia, Dorn, Julia, Schmalfeldt, Barbara, Schmitt, Manfred

“…Human kallikrein 5 (hK5; encoded by the KLK5 gene) is a secreted serine protease expressed in hormonally regulated tissues, including the breast and ovary. We…”
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