Search Results - "Borges Shimada, Ana Lucia"
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Retrospective application of ICH M7 to anti-hypertensive drugs in Brazil: Risk assessment of potentially mutagenic impurities
Published in Regulatory toxicology and pharmacology (01-08-2024)“…Potentially mutagenic impurities are likely to be formed in any drug substance, since their synthesis requires reactive intermediates which may also react with…”
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In vivo hydroquinone exposure alters circulating neutrophil activities and impairs LPS-induced lung inflammation in mice
Published in Toxicology (Amsterdam) (09-10-2011)“…Abstract Hydroquinone (HQ) is an environmental contaminant which causes immune toxicity. In this study, the effects of exposure to low doses of HQ on…”
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In vivo hydroquinone exposure impairs MCP-1 secretion and monocyte recruitment into the inflamed lung
Published in Toxicology (Amsterdam) (14-06-2012)“…Abstract Alveolar macrophages (AMs) are important cells in the resolution of the inflammatory process and they come into direct contact with inhaled…”
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Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
Published in International journal of nanomedicine (01-01-2015)“…Fully dispersible, cationic ultrasmall (7 nm diameter) superparamagnetic iron oxide nanoparticles, exhibiting high relaxivity (178 mM(-1)s(-1) in 0.47 T) and…”
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Anacardic Acids from Cashew Nuts Ameliorate Lung Damage Induced by Exposure to Diesel Exhaust Particles in Mice
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…Anacardic acids from cashew nut shell liquid, a Brazilian natural substance, have antimicrobial and antioxidant activities and modulate immune responses and…”
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In vivo hydroquinone exposure causes tracheal hyperresponsiveness due to TNF secretion by epithelial cells
Published in Toxicology letters (20-05-2012)“…► In vivo exposure to hydroquinone induces tracheal muscle hyperreactivity to methacholine. ► The effect depends on TNF secretion by trachea epithelial cells…”
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