Search Results - "Borges, Luciene"

Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells by Kimmey, Samuel C., Borges, Luciene, Baskar, Reema, Bendall, Sean C.

“…Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information…”
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Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells by Good, Zinaida, Borges, Luciene, Vivanco Gonzalez, Nora, Sahaf, Bita, Samusik, Nikolay, Tibshirani, Robert, Nolan, Garry P., Bendall, Sean C.

“…Selective differentiation of naive T cells into multipotent T cells is of great interest clinically for the generation of cell-based cancer immunotherapies…”
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Terminal deoxynucleotidyl transferase and CD84 identify human multi-potent lymphoid progenitors by Kim, YeEun, Calderon, Ariel A., Favaro, Patricia, Glass, David R., Tsai, Albert G., Ho, Daniel, Borges, Luciene, Greenleaf, William J., Bendall, Sean C.

“…Lymphoid specification in human hematopoietic progenitors is not fully understood. To better associate lymphoid identity with protein-level cell features, we…”
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An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells by Filareto, Antonio, Parker, Sarah, Darabi, Radbod, Borges, Luciene, Iacovino, Michelina, Schaaf, Tory, Mayerhofer, Timothy, Chamberlain, Jeffrey S., Ervasti, James M., McIvor, R. Scott, Kyba, Michael, Perlingeiro, Rita C. R.

“…Duchenne muscular dystrophy is a progressive and incurable neuromuscular disease caused by genetic and biochemical defects of the dystrophin–glycoprotein…”
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Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2 by Baik, June, Magli, Alessandro, Tahara, Naoyuki, Swanson, Scott A., Koyano-Nakagawa, Naoko, Borges, Luciene, Stewart, Ron, Garry, Daniel J., Kawakami, Yasuhiko, Thomson, James A., Perlingeiro, Rita C. R.

“…Mechanisms of haematopoietic and cardiac patterning remain poorly understood. Here we show that the BMP and Wnt signalling pathways are integrated in an…”
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Mass Cytometry Phenotyping of Human Granulocytes Reveals Novel Basophil Functional Heterogeneity by Vivanco Gonzalez, Nora, Oliveria, John-Paul, Tebaykin, Dmitry, Ivison, Geoffrey T., Mukai, Kaori, Tsai, Mindy M., Borges, Luciene, Nadeau, Kari C., Galli, Stephen J., Tsai, Albert G., Bendall, Sean C.

“…Basophils, the rarest granulocyte, play critical roles in parasite- and allergen-induced inflammation. We applied mass cytometry (CyTOF) to simultaneously…”
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An optimized protocol for phenotyping human granulocytes by mass cytometry by Vivanco Gonzalez, Nora, Oliveria, John-Paul, Tebaykin, Dmitry, Ivison, Geoffrey T., Mukai, Kaori, Tsai, Mindy M., Borges, Luciene, Nadeau, Kari C., Galli, Stephen J., Tsai, Albert G., Bendall, Sean C.

“…Granulocytes encompass diverse roles, from fighting off pathogens to regulating inflammatory processes in allergies. These roles are represented by distinct…”
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An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity by Glass, David R., Tsai, Albert G., Oliveria, John Paul, Hartmann, Felix J., Kimmey, Samuel C., Calderon, Ariel A., Borges, Luciene, Glass, Marla C., Wagar, Lisa E., Davis, Mark M., Bendall, Sean C.

“…B cells are capable of a wide range of effector functions including antibody secretion, antigen presentation, cytokine production, and generation of…”
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CHARACTERIZATION OF NATURAL KILLER CELL HEMATOPOIETIC PRECURSORS IN HUMAN HEMATOPOIESIS by Calderon, Ariel, Borges, Luciene, Favaro, Patricia, Glass, David, Bendall, Sean

“…Natural Killer (NK) cells have been characterized as cytotoxic lymphocytes that are key in regulating viral infections and combatting cancer. In contrast to B…”
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3011 – SINGLE CELL PROTEOMIC MAP OF PHENOTYPIC IDENTITY AND MOLECULAR REGULATORS TO REDEFINE HUMAN HEMATOPOIETIC PROGENITORS by Favaro, Patricia, Borges, Luciene, Glass, David R. Glass, Tebaykin, Dmitry, Shestopalov, Ilya, Bendall, Sean

“…Hematopoietic stem cell transplantation (HSCT) is a common treatment of various diseases, but the vast majority of HSPC therapeutic applications are crude in…”
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O centro cultural como equipamento disseminador de informação: um estudo sobre a ação do Galpão Cine Horto by Luciene Borges Ramos

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Serial transplantation reveals a critical role for endoglin in hematopoietic stem cell quiescence by Borges, Luciene, Oliveira, Vanessa K.P., Baik, June, Bendall, Sean C., Perlingeiro, Rita C.R.

“…Transforming growth factor β (TGF-β) is well known for its important function in hematopoietic stem cell (HSC) quiescence. However, the molecular mechanism…”
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Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis by Hartmann, Felix J, Simonds, Erin F, Vivanco, Nora, Bruce, Trevor, Borges, Luciene, Nolan, Garry P, Spitzer, Matthew H, Bendall, Sean C

“…The advent of mass cytometry (CyTOF ) has permitted simultaneous detection of more than 40 antibody parameters at the single-cell level, although a limited…”
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Proliferative tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells by Good, Zinaida, Borges, Luciene, Gonzalez, Nora Vivanco, Sahaf, Bita, Samusik, Nikolay, Tibshirani, Robert, Nolan, Garry P., Bendall, Sean C.

“…Selective differentiation of naïve T lymphocytes into multipotent T cells is of great interest clinically for the generation of cell-based cancer…”
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Structural and thermodynamic properties of liquid ethylene carbonate and propylene carbonate by Monte Carlo Simulations by Silva, Luciene Borges, Freitas, Luiz Carlos Gomide

“…Monte Carlo simulations have been used to investigate molecular association in pure liquid ethylene carbonate (EC) and propylene carbonate (PC). Standard force…”
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Etv2 Is Expressed in the Yolk Sac Hematopoietic and Endothelial Progenitors and Regulates Lmo2 Gene Expression by Koyano-Nakagawa, Naoko, Kweon, Junghun, Iacovino, Michelina, Shi, Xiaozhong, Rasmussen, Tara L., Borges, Luciene, Zirbes, Katie M., Li, Tongbin, Perlingeiro, Rita C. R., Kyba, Michael, Garry, Daniel J.

“…During embryogenesis, the endothelial and the hematopoietic lineages first appear during gastrulation in the blood island of the yolk sac. We have previously…”
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Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment by Baskar, Reema, Chen, Amy F., Favaro, Patricia, Reynolds, Warren, Mueller, Fabian, Borges, Luciene, Jiang, Sizun, Park, Hyun Shin, Kool, Eric T., Greenleaf, William J., Bendall, Sean C.

“…Master transcription factors (TFs) directly regulate present and future cell states by binding DNA regulatory elements and driving gene-expression programs…”
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A critical role for endoglin in the emergence of blood during embryonic development by Borges, Luciene, Iacovino, Michelina, Mayerhofer, Timothy, Koyano-Nakagawa, Naoko, Baik, June, Garry, Daniel J., Kyba, Michael, Letarte, Michelle, Perlingeiro, Rita C.R.

“…Much remains unknown about the signals that induce early mesoderm to initiate hematopoietic differentiation. Here, we show that endoglin (Eng), a receptor for…”
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Pax3 and Tbx5 Specify Whether PDGFRα+ Cells Assume Skeletal or Cardiac Muscle Fate in Differentiating Embryonic Stem Cells by Magli, Alessandro, Schnettler, Erin, Swanson, Scott A., Borges, Luciene, Hoffman, Kirsta, Stewart, Ron, Thomson, James A., Keirstead, Susan A., Perlingeiro, Rita C. R.

“…Embryonic stem cells (ESCs) represent an ideal model to study how lineage decisions are established during embryonic development. Using a doxycycline‐inducible…”
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ARHGAP21 modulates FAK activity and impairs glioblastoma cell migration by Bigarella, Carolina Louzão, Borges, Luciene, Costa, Fernando Ferreira, Saad, Sara Terezinha Olalla

“…Glioblastoma multiforme is highly aggressive and is the most common glial tumor type. Although there have been advances in treatment, the average survival…”
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