Search Results - "Borges, Júlio César"
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Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)
Published in PloS one (05-08-2015)“…Dysregulation of pre-mRNA splicing machinery activity has been related to the biogenesis of several diseases. The serine/arginine-rich protein kinase family…”
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The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs
Published in PloS one (07-09-2018)“…Purine nucleoside phosphorylases (PNPs) play an important role in the blood fluke parasite Schistosoma mansoni as a key enzyme of the purine salvage pathway…”
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Design, synthesis, SAR, and biological evaluation of new 4-(phenylamino)thieno[2,3- b]pyridine derivatives
Published in Bioorganic & medicinal chemistry (15-08-2006)“…We performed the design, synthesis, and the structure–activity relationship studies of 13 new derivatives of thieno[2,3- b]pyridine system pointing the…”
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Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity
Published in ACS infectious diseases (09-04-2021)“…Antimalarial drugs with novel modes of action and wide therapeutic potential are needed to pave the way for malaria eradication. Violacein is a natural…”
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New Insights into Hsp90 Structural Plasticity Revealed by cryoEM
Published in BioChem (04-04-2024)“…Heat Shock Protein 90 (Hsp90) acts as a crucial molecular chaperone, playing an essential role in activating numerous signaling proteins. The intricate…”
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Structural studies of prephenate dehydratase from Mycobacterium tuberculosis H37Rv by SAXS, ultracentrifugation, and computational analysis
Published in Proteins, structure, function, and bioinformatics (01-09-2008)“…Tuberculosis (TB) is one of the most common infectious diseases known to man and responsible for millions of human deaths in the world. The increasing…”
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Exploiting supramolecular interactions to produce bevacizumab-loaded nanoparticles for potential mucosal delivery
Published in European polymer journal (01-06-2018)“…[Display omitted] •Drug delivery platform integrating mucus penetranting and mucoadhesive agents.•Self-assembly studies conducted using three classes of…”
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Cantos, curas e alimentos: reflexões sobre regimes de conhecimento Krahô
Published in Revista de antropologia (São Paulo) (07-12-2012)“…Este artigo propõe uma aproximação compreensiva aos regimes de conhecimento do povo indígena Krahô. Tal qual o desenho enredado de caminhos (prỳ) que…”
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“A sociedade brasileira nos fez pobres”: assistência social e autonomia étnica dos povos indígenas. O caso de Dourados, Mato Grosso do Sul
Published in Horizontes antropológicos (01-12-2016)“…O artigo pretende analisar a relação dos povos indígenas com a política pública de assistência social (AS) no Brasil. Com base em dados coletados durante…”
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Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi
Published in International journal for parasitology -- drugs and drug resistance (01-12-2016)“…Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited…”
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Aqui ninguém domina ninguém: sentidos do trabalho e produção de saúde para trabalhadores de assentamento do Movimento dos Trabalhadores Rurais Sem Terra
Published in Cadernos de saúde pública (01-08-2013)“…Este artigo discute os resultados parciais da pesquisa qualitativa que visou a analisar os modos de vida e significados atribuídos por assentados do Movimento…”
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Anti-EGFR liquid crystalline nanodispersions for docetaxel delivery: Formulation, characterization and cytotoxicity in cancer cells
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (20-03-2021)“…[Display omitted] Prostate cancer is one of the most frequent neoplasms, associated with high mortality. Some factors may intensify its aggressiveness, for…”
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Primary Angioplasty for Cardiac Allograft Vasculopathy Presenting as ST-Elevation Acute Myocardial Infarction during Endomyocardial Biopsy
Published in Case reports in transplantation (01-01-2013)“…Cardiac allograft vasculopathy is still a major issue, with significative mortality in heart transplant patients, and the best therapeutic options are not yet…”
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RELAÇÕES DE PODER E DE TRABALHO NA FAZENDA-ROÇA GOIANA
Published in Revista Pegada Electrônica (19-01-2017)“…Resumo:O que se pretende neste artigo é fazer uma análise da relação de poder e trabalho constituinte no mundo sertanejo de Goiás sob a perspectiva da luta de…”
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Insights into the full-length SRPK2 structure and its hydrodynamic behavior
Published in International journal of biological macromolecules (15-09-2019)“…The serine/arginine-rich protein kinase 2 (SRPK2) has been reported as upregulated in several cancer types, with roles in hallmarks such as cell migration,…”
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Tonin in rat heart with experimental hypertrophy
Published in American journal of physiology. Heart and circulatory physiology (01-06-2003)“…The present study was undertaken to determine tonin expression and activity in rat heart presenting isoproterenol-induced hypertrophy. Renin,…”
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“A sociedade brasileira nos fez pobres”: assistência social e autonomia étnica dos povos indígenas. O caso de Dourados, Mato Grosso do Sul
Published in Horizontes antropológicos (01-12-2016)“…Resumo O artigo pretende analisar a relação dos povos indígenas com a política pública de assistência social (AS) no Brasil. Com base em dados coletados…”
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Aspergillus fumigatus Hsp90 interacts with the main components of the cell wall integrity pathway and cooperates in heat shock and cell wall stress adaptation
Published in Cellular microbiology (01-02-2021)“…The initiation of Aspergillus fumigatus infection occurs via dormant conidia deposition into the airways. Therefore, conidial germination and subsequent hyphal…”
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Magnetic Natural Coagulants for Plastic Recycling Industry Wastewater Treatability
Published in Water (Basel) (01-04-2023)“…The plastic recycling industry generates a high volume of wastewaters. In this study, an unprecedented use of Moringa oleifera and tannin (Acacia mearnsii…”
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