Search Results - "Borges, C C"
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Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria
Published in Angewandte Chemie International Edition (09-09-2019)“…A substantial challenge worldwide is emergent drug resistance in malaria parasites against approved drugs, such as chloroquine (CQ). To address these unsolved…”
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Pot1 promotes telomere DNA replication via the Stn1-Ten1 complex in fission yeast
Published in Nucleic acids research (11-12-2023)“…Abstract Telomeres are nucleoprotein complexes that protect the chromosome-ends from eliciting DNA repair while ensuring their complete duplication. Pot1 is a…”
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Oil Produced Water treatment for oil removal by an integration of coalescer bed and microfiltration membrane processes
Published in Journal of membrane science (01-11-2014)Get full text
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Antioxidant Activity of an Aqueous Leaf Extract from Uncaria tomentosa and Its Major Alkaloids Mitraphylline and Isomitraphylline in Caenorhabditis elegans
Published in Molecules (Basel, Switzerland) (10-09-2019)“…(Rubiaceae) has a recognized therapeutic potential against various diseases associated with oxidative stress. The aim of this research was to evaluate the…”
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Emerging insights into hypothalamic‐pituitary‐gonadal axis regulation and interaction with stress signalling
Published in Journal of neuroendocrinology (01-10-2018)“…Reproduction and fertility are regulated via hormones of the hypothalamic‐pituitary‐gonadal (HPG) axis. Control of this reproductive axis occurs at all levels,…”
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High neutrophil to lymphocytes ratio is associated with sarcopenia risk in hospitalized cancer patients
Published in Clinical nutrition (Edinburgh, Scotland) (01-01-2021)“…Systemic inflammation has been reported as a new predictor for cancer outcomes. This study aimed i) to identify the neutrophil to lymphocytes ratio (NLR)…”
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Portfolio Optimization Via Online Gradient Descent and Risk Control
Published in Computational economics (01-06-2023)“…Since Markowitz’s initial contribution in 1952, portfolio selection has undoubtedly been one of the most challenging topics in finance. The development of…”
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IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
Published in Nature communications (04-04-2017)“…Patients who survive sepsis can develop long-term immune dysfunction, with expansion of the regulatory T (Treg) cell population. However, how Treg cells…”
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Nutritional value and antioxidant compounds during the ripening and after domestic cooking of bananas and plantains
Published in Food research international (01-06-2020)“…[Display omitted] •Plantains and cooking bananas presented a high content of resistant starch.•Peel showed superior phenolic compounds and minerals levels than…”
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Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex
Published in Glia (01-02-2023)“…For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination focused primarily on excitatory cells. Recent…”
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Population homogeneity for the antibody response to COVID-19 BNT162b2/Comirnaty vaccine is only reached after the second dose across all adult age ranges
Published in Nature communications (10-01-2022)“…While mRNA vaccines are administrated worldwide in an effort to contain the COVID-19 pandemic, the heterogeneity of the humoral immune response they induce at…”
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From hidden hearing loss to supranormal auditory processing by neurotrophin 3-mediated modulation of inner hair cell synapse density
Published in PLoS biology (27-06-2024)“…Loss of synapses between spiral ganglion neurons and inner hair cells (IHC synaptopathy) leads to an auditory neuropathy called hidden hearing loss (HHL)…”
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Acute food deprivation-induced relapse to heroin seeking after short and long punishment-imposed abstinence in male rats
Published in Psychopharmacology (01-03-2023)“…Rational Stress is a major trigger for drug relapse in humans and animal models, even after prolonged abstinence. However, animal models for stress-induced…”
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Impact of Resistance Training in Chronic Obstructive Pulmonary Disease Patients During Periods of Acute Exacerbation
Published in Archives of physical medicine and rehabilitation (01-09-2014)“…Abstract Objective To evaluate the effects of whole-body resistance training on exercise capacity, health-related quality of life (HRQOL), and muscle strength…”
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The regulation of the thermal stability and affinity of the HSPA5 (Grp78/BiP) by clients and nucleotides is modulated by domains coupling
Published in Biochimica et biophysica acta. Proteins and proteomics (01-09-2024)“…The HSPA5 protein (BiP/Grp78) serves as a pivotal chaperone in maintaining cellular protein quality control. As a member of the human HSP70 family, HSPA5…”
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Spatio-temporal dynamics of phytoplankton community in a well-mixed temperate estuary (Sado Estuary, Portugal)
Published in Scientific reports (30-09-2022)“…Estuaries are highly productive ecosystems, which are strongly affected by several anthropogenic pressures. Phytoplankton is a key element for assessing the…”
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High neutrophil to lymphocytes ratio is associated with nutritional risk in hospitalised, unselected cancer patients: a cross-sectional study
Published in Scientific reports (24-08-2021)“…Cancer patients possess metabolic and pathophysiological changes and an inflammatory environment that leads to malnutrition. This study aimed to (i) determine…”
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Ripening and cooking processes influence the carotenoid content in bananas and plantains (Musa spp.)
Published in Food research international (01-10-2019)“…In bananas, the major carotenoids are α- and β-carotene, which give this fruit great potential in biofortification programs. The carotenoid content in pulp and…”
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Tailoring strength of nanocellulose foams by electrostatic complexation
Published in Carbohydrate polymers (15-03-2021)“…[Display omitted] •A simple pathway for preparation of all- nanocellulose foams was developed.•CNFs dispersions are a mixture of clusters and networks of…”
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Cochlear Neurotrophin‐3 overexpression at mid‐life prevents age‐related inner hair cell synaptopathy and slows age‐related hearing loss
Published in Aging cell (01-10-2022)“…Age‐related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly. This progressive pathology often has psychological and medical…”
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