Search Results - "Borg, John J."
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Exposure of wetlands important for nonbreeding waterbirds to sea-level rise in the Mediterranean
Published in Conservation biology (16-05-2024)“…Sea-level rise (SLR) is expected to cause major changes to coastal wetlands, which are among the world's most vulnerable ecosystems and are critical for…”
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Gap analysis of the Ramsar site network at 50: over 150 important Mediterranean sites for wintering waterbirds omitted
Published in Biodiversity and conservation (01-09-2021)“…The Mediterranean Basin is a biodiversity hotspot. Wetlands make a key contribution to this status, but many of them remain outside the Ramsar network fifty…”
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3
Pharmaceutical issues during the review of European Marketing Authorisation Applications in Malta
Published in Pharmaceutical development and technology (03-07-2018)“…The aim of this study was to identify pharmaceutical issues encountered during regulatory review in European Procedures. A database of issues from Day 70…”
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Maltese bats show phylogeographic affiliation with North-Africa: implications for conservation
Published in Hystrix (01-01-2019)“…In the Mediterranean region, cryptic diversity of bats is common. As distinct genetic lineages should be managed independently for conservation, insight into…”
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Potent inhibition of human cardiac potassium (HERG) channels by the anti-estrogen agent clomiphene—without QT interval prolongation
Published in Biochemical and biophysical research communications (28-05-2004)“…The acquired form of the long-QT syndrome (LQTS) is a major safety consideration for the development and subsequent use of both cardiac and non-cardiac drugs;…”
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In support of the European Union biosimilar framework
Published in Nature biotechnology (01-08-2012)Get full text
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Inhibitory effects of the antiestrogen agent clomiphene on cardiac sarcolemmal anionic and cationic currents
Published in The Journal of pharmacology and experimental therapeutics (01-10-2002)“…The aim of this study was to determine the effects of the antiestrogen agent clomiphene on cardiac anionic and cationic sarcolemmal ion channels. Whole-cell…”
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Multimodal management as requirement for the clinical use of anticachexia drugs - a regulatory and a clinical perspective
Published in Current opinion in supportive & palliative care (01-12-2015)“…Multimodal management has been proposed as key to any effective drug intervention in cachexia. This article attempts to reflect on clinical and regulatory…”
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Global climate patterns explain range-wide synchronicity in survival of a migratory seabird
Published in Global change biology (01-01-2009)“…To predict the impact of climate change over the whole species distribution range, comparison of adult survival variations over large spatial scale is of…”
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Is the Yelkouan shearwater Puffinus yelkouan threatened by low adult survival probabilities?
Published in Biological conservation (01-09-2011)“…► We estimate adult survival probabilities at colonies in Malta and France. ► Survival probabilities of breeding adults are too low to sustain stable…”
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First description of post-fledging migration of Maltese Cory's Shearwaters Calonectris diomedea diomedea
Published in Ringing & migration (01-12-2011)“…Three juvenile Cory's Shearwaters Calonectris diomedea diomedea were fitted with back-mounted satellite tags and tracked during post-fledging migration. The…”
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Cardiac chloride channels: physiology, pharmacology and approaches for identifying novel modulators of activity
Published in Drug Discovery Today (01-11-2000)“…Drugs that block cardiac cation channels have been marketed as the therapeutic answer to cardiac arrhythmia. However, such molecules have been only moderately…”
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Post-fledging dispersal of Maltese Yelkouan Shearwaters Puffinus yelkouan
Published in Ringing & migration (01-12-2011)“…Satellite tags were attached to ten juvenile Yelkouan Shearwaters from a breeding colony in Malta to study post-fledging dispersal patterns. Of the eight birds…”
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Actions of pyrethroid insecticides on sodium currents, action potentials, and contractile rhythm in isolated mammalian ventricular myocytes and perfused hearts
Published in The Journal of pharmacology and experimental therapeutics (01-09-2001)“…Pyrethroid insecticides are known to modify neuronal sodium channels, inducing persistent, steady-state sodium current at depolarized membrane potentials…”
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Differential pharmacology of the cardiac anionic background current IAB
Published in European journal of pharmacology (27-08-2007)Get full text
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Genetic Characterization of Over Hundred Years Old Caretta caretta specimens from Italian and Maltese Museums
Published in Acta herpetologica (2011)Get full text
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Seabird mortality from longline fishing in the Mediterranean Sea and Macaronesian waters: a review and a way forward
Published in Scientia marina (01-07-2003)“…A country-by-country review of seabird mortality from longline fishing in the Mediterranean Sea and in Macaronesian waters shows a paucity of data. Of 12…”
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DIFFERENTIAL EFFECTS OF PYRETHROIDS ON VOLUME-SENSITIVE ANION AND ORGANIC OSMOLYTE PATHWAYS
Published in Clinical and experimental pharmacology & physiology (01-03-2004)“…SUMMARY 1. There are no effective ways of screening for potential modulators of volume‐regulated anion channels in their native cell type. Generally, cell…”
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Tefluthrin Modulates a Novel Anionic Background Conductance (IAB) in Guinea-Pig Ventricular Myocytes
Published in Biochemical and biophysical research communications (22-03-2002)“…This report describes for the first time a novel anionic background current (IAB) identified in guinea-pig isolated ventricular myocytes. It also shows that…”
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Global assessment of marine plastic exposure risk for oceanic birds
Published in Nature communications (04-07-2023)“…Plastic pollution is distributed patchily around the world’s oceans. Likewise, marine organisms that are vulnerable to plastic ingestion or entanglement have…”
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