Search Results - "Borg, John J."

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    Pharmaceutical issues during the review of European Marketing Authorisation Applications in Malta by Chetcuti, Michael, Serracino-Inglott, Anthony, Flores, Gavril, Borg, John J

    Published in Pharmaceutical development and technology (03-07-2018)
    “…The aim of this study was to identify pharmaceutical issues encountered during regulatory review in European Procedures. A database of issues from Day 70…”
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    Journal Article
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    Maltese bats show phylogeographic affiliation with North-Africa: implications for conservation by Batsleer, Femke, Portelli, Elena, Borg, John J, Kiefer, Andreas, Veith, Michael, Dekeukeleire, Daan

    Published in Hystrix (01-01-2019)
    “…In the Mediterranean region, cryptic diversity of bats is common. As distinct genetic lineages should be managed independently for conservation, insight into…”
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    Potent inhibition of human cardiac potassium (HERG) channels by the anti-estrogen agent clomiphene—without QT interval prolongation by Yuill, Kathryn H, Borg, John J, Ridley, John M, Milnes, James T, Witchel, Harry J, Paul, Ashok A, Kozlowski, Roland Z, Hancox, Jules C

    “…The acquired form of the long-QT syndrome (LQTS) is a major safety consideration for the development and subsequent use of both cardiac and non-cardiac drugs;…”
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    Inhibitory effects of the antiestrogen agent clomiphene on cardiac sarcolemmal anionic and cationic currents by Borg, John J, Yuill, Kathryn H, Hancox, Jules C, Spencer, Ian C, Kozlowski, Roland Z

    “…The aim of this study was to determine the effects of the antiestrogen agent clomiphene on cardiac anionic and cationic sarcolemmal ion channels. Whole-cell…”
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    Journal Article
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    Multimodal management as requirement for the clinical use of anticachexia drugs - a regulatory and a clinical perspective by Borg, John J., Anker, Stefan D., Rosano, Giuseppe, Serracino-Inglott, Anthony, Strasser, Florian

    “…Multimodal management has been proposed as key to any effective drug intervention in cachexia. This article attempts to reflect on clinical and regulatory…”
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    Global climate patterns explain range-wide synchronicity in survival of a migratory seabird by JENOUVRIER, STEPHANIE, THIBAULT, JEAN-CLAUDE, VIALLEFONT, ANNE, VIDAL, PATRICK, RISTOW, DIETRICH, MOUGIN, JEAN-LOUIS, BRICHETTI, PIERANDREA, BORG, JOHN J., BRETAGNOLLE, VINCENT

    Published in Global change biology (01-01-2009)
    “…To predict the impact of climate change over the whole species distribution range, comparison of adult survival variations over large spatial scale is of…”
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    Is the Yelkouan shearwater Puffinus yelkouan threatened by low adult survival probabilities? by Oppel, Steffen, Raine, André F., Borg, John J., Raine, Helen, Bonnaud, Elsa, Bourgeois, Karen, Breton, André R.

    Published in Biological conservation (01-09-2011)
    “…► We estimate adult survival probabilities at colonies in Malta and France. ► Survival probabilities of breeding adults are too low to sustain stable…”
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    First description of post-fledging migration of Maltese Cory's Shearwaters Calonectris diomedea diomedea by Raine, André, Borg, John J., Raine, Helen

    Published in Ringing & migration (01-12-2011)
    “…Three juvenile Cory's Shearwaters Calonectris diomedea diomedea were fitted with back-mounted satellite tags and tracked during post-fledging migration. The…”
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    Cardiac chloride channels: physiology, pharmacology and approaches for identifying novel modulators of activity by Mulvaney, Andrew W, Spencer, C.Ian, Culliford, Steven, Borg, John J, Davies, Stephen G, Kozlowski, Roland Z

    Published in Drug Discovery Today (01-11-2000)
    “…Drugs that block cardiac cation channels have been marketed as the therapeutic answer to cardiac arrhythmia. However, such molecules have been only moderately…”
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    Book Review Journal Article
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    Post-fledging dispersal of Maltese Yelkouan Shearwaters Puffinus yelkouan by Raine, André F., Raine, Helen, Borg, John J., Meirinho, Ana

    Published in Ringing & migration (01-12-2011)
    “…Satellite tags were attached to ten juvenile Yelkouan Shearwaters from a breeding colony in Malta to study post-fledging dispersal patterns. Of the eight birds…”
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    Journal Article
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    Actions of pyrethroid insecticides on sodium currents, action potentials, and contractile rhythm in isolated mammalian ventricular myocytes and perfused hearts by Spencer, C I, Yuill, K H, Borg, J J, Hancox, J C, Kozlowski, R Z

    “…Pyrethroid insecticides are known to modify neuronal sodium channels, inducing persistent, steady-state sodium current at depolarized membrane potentials…”
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    Seabird mortality from longline fishing in the Mediterranean Sea and Macaronesian waters: a review and a way forward by Cooper, John, Baccetti, Nicola, Belda, Eduardo J., Borg, John J., Oro, Daniel, Papaconstantinou, Costas, Sánchez, Antonio

    Published in Scientia marina (01-07-2003)
    “…A country-by-country review of seabird mortality from longline fishing in the Mediterranean Sea and in Macaronesian waters shows a paucity of data. Of 12…”
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    DIFFERENTIAL EFFECTS OF PYRETHROIDS ON VOLUME-SENSITIVE ANION AND ORGANIC OSMOLYTE PATHWAYS by Culliford, Steve J, Borg, John J, O'Brien, Martin J, Kozlowski, Roland Z

    “…SUMMARY 1. There are no effective ways of screening for potential modulators of volume‐regulated anion channels in their native cell type. Generally, cell…”
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    Tefluthrin Modulates a Novel Anionic Background Conductance (IAB) in Guinea-Pig Ventricular Myocytes by Borg, John J., Hancox, Jules C., Ian Spencer, C., Kozlowski, Roland Z.

    “…This report describes for the first time a novel anionic background current (IAB) identified in guinea-pig isolated ventricular myocytes. It also shows that…”
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    Global assessment of marine plastic exposure risk for oceanic birds by Clark, Bethany L., Pearmain, Elizabeth J., Rouyer, Marie-Morgane, Clay, Thomas A., Manica, Andrea, Adams, Josh, Albores-Barajas, Yuri V., Araujo, Deusa Teixeira, Arnould, John P. Y., Beck, Jessie, Booth Jones, Katherine A., Bretagnolle, Vincent, Bried, Joël, Briskie, James V., Brooke, M. de L., Brownlie, Katherine C., Bugoni, Leandro, Calabrese, Licia, Carey, Mark J., Carle, Ryan D., Carlile, Nicholas, Catry, Teresa, Cecere, Jacopo G., Ceia, Filipe R., Cianchetti-Benedetti, Marco, Clarke, Rohan H., Congdon, Bradley C., Deakin, Zoe, Dell’Omo, Giacomo, Delord, Karine, Dilley, Ben J., Dunphy, Brendon J., Fayet, Annette L., Felis, Jonathan J., Freeman, Amanda N. D., García, David, Forero, Manuela G., Grecian, W. James, Halpin, Luke R., Helberg, Morten, Helgason, Halfdan H., Hereward, Hannah F. R., Hindell, Mark A., Hodum, Peter J., Jessopp, Mark, Jones, Carl G., Jones, Christopher W., Kane, Adam, Kapelj, Sven, Kim, Yuna, Kirk, Holly, Kolbeinsson, Yann, Kraemer, Philipp L., Krüger, Lucas, Lago, Paulo, Landers, Todd J., Lavers, Jennifer L., Le Corre, Matthieu, Louzao, Maite, Madeiros, Jeremy, Matsumoto, Sakiko, McDuie, Fiona, Medrano, Fernando, Neves, Verónica C., Norris, Ken, Oro, Daniel, Owen, Ellie, Paiva, Vítor H., Pala, David, Pina, Ariete T. Moreira, Pollet, Ingrid L., Porter, Benjamin J., Poupart, Timothée A., Quillfeldt, Petra, Raine, Andre F., Ramírez, Iván, Ravache, Andreas, Rayner, Matt J., Reid, Timothy A., Robertson, Gregory J., Rollinson, Dominic P., Rotger, Andreu, Ruhomaun, Kevin, Ruiz, Asunción, Saldanha, Sarah, Sanz-Aguilar, Ana, Sigurðsson, Ingvar A., Silva, Mónica C., Soldatini, Cecilia, Strøm, Hallvard, Tatayah, Vikash R. V., Thomas, Robert J., Thompson, Paul M., Thórarinsson, Thorkell L., Vidal, Eric, Waugh, Susan M., Wittmer, Heiko U., Yamamoto, Takashi, Zavalaga, Carlos B., Zino, Francis J.

    Published in Nature communications (04-07-2023)
    “…Plastic pollution is distributed patchily around the world’s oceans. Likewise, marine organisms that are vulnerable to plastic ingestion or entanglement have…”
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