Search Results - "Borer, Christine"

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks by Couto, C Anne-Marie, Wang, Hong-Yu, Green, Joanna C A, Kiely, Rhian, Siddaway, Robert, Borer, Christine, Pears, Catherine J, Lakin, Nicholas D

“…Poly adenosine diphosphate (ADP)-ribosylation (PARylation) by poly ADP-ribose (PAR) polymerases (PARPs) is an early response to DNA double-strand breaks…”
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The role of ADP-ribosylation in regulating DNA double-strand break repair by Pears, Catherine J., Couto, C. Anne-Marie, Wang, Hong-Yu, Borer, Christine, Kiely, Rhian, Lakin, Nicholas D.

“…ADP-ribosylation is the post translational modification of proteins catalysed by ADP-ribosyltransferases (ARTs). ADP-ribosylation has been implicated in a wide…”
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Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution by Rodriguez-Lopez, Ana M, Whitby, Matthew C, Borer, Christine M, Bachler, Marcus A, Cox, Lynne S

“…The progeroid Werner's syndrome (WS) represents the best current model of human aging. It is caused by loss of the WRN helicase/exonuclease, resulting in high…”
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DNA double-strand break repair pathway choice in Dictyostelium by Hsu, Duen-Wei, Kiely, Rhian, Couto, C Anne-Marie, Wang, Hong-Yu, Hudson, Jessica J R, Borer, Christine, Pears, Catherine J, Lakin, Nicholas D

“…DNA double-strand breaks (DSBs) can be repaired by homologous recombination (HR) or non-homologous end joining (NHEJ). The mechanisms that govern whether a DSB…”
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