Search Results - "Boren, Babette M."

High Hematocrit Resulting from Administration of Erythropoiesis-stimulating Agents Is Not Fully Predictive of Mortality or Toxicities in Preclinical Species by Andrews, Dina A., Pyrah, Ian T. G., Boren, Babette M., Tannehill-Gregg, Sarah H., Lightfoot-Dunn, Ruth M.

“…We conducted a retrospective analysis of publicly available preclinical toxicology studies with erythropoiesis-stimulating agents (ESAs) to examine common…”
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Dose-related Differences in the Pharmacodynamic and Toxicologic Response to a Novel Hyperglycosylated Analog of Recombinant Human Erythropoietin in Sprague-Dawley Rats with Similarly High Hematocrit by Andrews, Dina A., Boren, Babette M., Turk, James R., Boyce, Rogely W., He, Yudong D., Hamadeh, Hisham K., Mytych, Daniel T., Barger, Troy E., Salimi-Moosavi, Hossein, Sloey, Bethlyn, Elliott, Steve, McElroy, Patricia, Sinclair, Angus M., Shimamoto, Grant, Pyrah, Ian T. G., Lightfoot-Dunn, Ruth M.

“…We recently reported results that erythropoiesis-stimulating agent (ESA)–related thrombotic toxicities in preclinical species were not solely dependent on a…”
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Cytokines Associated with Increased Erythropoiesis in Sprague-Dawley Rats Administered a Novel Hyperglycosylated Analog of Recombinant Human Erythropoietin by Andrews, Dina A., Hamadeh, Hisham K., He, Yudong D., Boren, Babette M., Turk, James R., Boyce, Rogely W., Mytych, Daniel T., Barger, Troy E., Salimi-Moosavi, Hossein, Sloey, Bethlyn, Elliott, Steve, McElroy, Patricia, Sinclair, Angus M., Shimamoto, Grant, Pyrah, Ian T. G., Lightfoot-Dunn, Ruth M.

“…We previously reported an increased incidence of thrombotic toxicities in Sprague-Dawley rats administered the highest dose level of a hyperglycosylated analog…”
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Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐IL‐15 antibody Hu714MuXHu in cynomolgus monkeys by Pan, Wei. J., Li, Hong, Xiao, Jim J., Horner, Michelle J., Lebrec, Herve N., Butz, Eric A., Kaliyaperumal, Arunan, Cheah, Tsui C., Ortiz, Robert C., Prokop, Samantha P., Buntich, Sabina A., Boren, Babette M., Wolford, Suzanne T., Tsuji, Wayne H., Wienkers, Larry C., Köck, Kathleen

“…Hu714MuXHu is a recombinant chimeric murine‐human monoclonal antibody directed against interleukin‐15 (IL‐15), a proinflammatory cytokine associated with…”
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Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐ IL ‐15 antibody Hu714Mu XH u in cynomolgus monkeys by Pan, Wei. J., Li, Hong, Xiao, Jim J., Horner, Michelle J., Lebrec, Herve N., Butz, Eric A., Kaliyaperumal, Arunan, Cheah, Tsui C., Ortiz, Robert C., Prokop, Samantha P., Buntich, Sabina A., Boren, Babette M., Wolford, Suzanne T., Tsuji, Wayne H., Wienkers, Larry C., Köck, Kathleen

“…Abstract Hu714Mu XH u is a recombinant chimeric murine‐human monoclonal antibody directed against interleukin‐15 ( IL ‐15), a proinflammatory cytokine…”
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