Search Results - "Borea, Roberto"

FGFR a promising druggable target in cancer: molecular biology and new drugs by Porta, Rut, Borea, Roberto, Coelho, Andreia, Khan, Shahnavaj, Araujo, Antonio, Reclusa, Pablo, Franchina, Tindara, Van Der Steen, Nele, Van Dam, Peter, Ferri, Jose, Sirera, Rafael, Naing, Aung, Hong, David, Rolfo, Christian

“…Abstract Introduction The Fibroblast Growth Factor Receptor (FGFR) family consists of Tyrosine Kinase Receptors (TKR) involved in several biological functions…”
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Beyond BRCA: The Emerging Significance of DNA Damage Response and Personalized Treatment in Pancreatic and Prostate Cancer Patients by Dalmasso, Bruna, Puccini, Alberto, Catalano, Fabio, Borea, Roberto, Iaia, Maria Laura, Bruno, William, Fornarini, Giuseppe, Sciallero, Stefania, Rebuzzi, Sara Elena, Ghiorzo, Paola

“…The germline and/or somatic pathogenic variants (PVs) are key players in the hereditary predisposition and therapeutic response for breast, ovarian and, more…”
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Ovarian Suppression: Early Menopause and Late Effects by Molinelli, Chiara, Jacobs, Flavia, Nader-Marta, Guilherme, Borea, Roberto, Scavone, Graziana, Ottonello, Silvia, Fregatti, Piero, Villarreal-Garza, Cynthia, Bajpai, Jyoti, Kim, Hee Jeong, Puglisi, Silvia, de Azambuja, Evandro, Lambertini, Matteo

“…Opinion statement Around 90% of breast tumours are diagnosed in the early stage, with approximately 70% being hormone receptor-positive. The cornerstone of…”
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Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study by Ravera, Francesco, Borea, Roberto, Cirmena, Gabriella, Dameri, Martina, Ferrando, Lorenzo, Gallo, Maurizio, Casini, Cecilia, Fallani, Neri, Stabile, Mario, Barbero, Valentina, Murialdo, Roberto, Tixi, Lucia, Cappuccio, Margherita, Cuboni, Andrea, Sivieri, Irene, Fornarini, Giuseppe, De Maria, Andrea, Ballestrero, Alberto, Zoppoli, Gabriele

“…Little is known about SARS-CoV-2 seroconversion in asymptomatic patients affected by solid cancer, and whether it is associated with specific transcriptomics…”
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Patterns of care at the end of life: a retrospective study of Italian patients with advanced breast cancer by Giannubilo, Irene, Battistuzzi, Linda, Blondeaux, Eva, Ruelle, Tommaso, Poggio, Francesca Benedetta, Buzzatti, Giulia, D'Alonzo, Alessia, Della Rovere, Federica, Latocca, Maria Maddalena, Molinelli, Chiara, Razeti, Maria Grazia, Nardin, Simone, Arecco, Luca, Perachino, Marta, Favero, Diletta, Borea, Roberto, Pronzato, Paolo, Del Mastro, Lucia, Bighin, Claudia

“…To better understand the type of care offered to Italian patients with advanced breast cancer at the End-of-Life (EoL), we conducted a retrospective…”
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Beyond the Prognostic Value of 2-[ 18 F]FDG PET/CT in Prostate Cancer: A Case Series and Literature Review Focusing on the Diagnostic Value and Impact on Patient Management by Borea, Roberto, Favero, Diletta, Miceli, Alberto, Donegani, Maria Isabella, Raffa, Stefano, Gandini, Annalice, Cremante, Malvina, Marini, Cecilia, Sambuceti, Gianmario, Zanardi, Elisa, Morbelli, Silvia, Fornarini, Giuseppe, Rebuzzi, Sara Elena, Bauckneht, Matteo

“…The role of 2-deoxy-2-[ F]fluoro-D-glucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) in the management of prostate cancer (PCa) patients is…”
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Targeting the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Colorectal Cancer by Catalano, Fabio, Borea, Roberto, Puglisi, Silvia, Boutros, Andrea, Gandini, Annalice, Cremante, Malvina, Martelli, Valentino, Sciallero, Stefania, Puccini, Alberto

“…Major advances have been made in CRC treatment in recent years, especially in molecularly driven therapies and immunotherapy. Despite this, a large number of…”
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Current practices in oncofertility counseling: updated evidence on fertility preservation and post-treatment pregnancies in young women affected by early breast cancer by Arecco, Luca, Borea, Roberto, Magaton, Isotta Martha, Janković, Kristina, Mariamizde, Elene, Stana, Mihaela, Scavone, Graziana, Ottonello, Silvia, Spinaci, Stefano, Genova, Carlo, de Azambuja, Evandro, Lambertini, Matteo

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Rare anti-VEGFR therapy-induced toxicity and long-term response to immunotherapy in a rare non-clear cell renal cell carcinoma patient by Catalano, Fabio, Rebuzzi, Sara Elena, Murianni, Veronica, Damassi, Alessandra, Martelli, Valentino, Borea, Roberto, Rollandi, Gian Andrea, Fornarini, Giuseppe

“…Advanced non-clear cell renal cell carcinoma (nccRCC) has a poor prognosis and clinical data on the therapeutic options currently available, including…”
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Rare anti-VEGFR therapy-induced toxicity and long-term response to immunotherapy in a rare non-clear cell renal cell carcinoma patient by Catalano, Fabio, Rebuzzi, Sara Elena, Murianni, Veronica, Damassi, Alessandra, Martelli, Valentino, Borea, Roberto, Rollandi, Gian Andrea, Fornarini, Giuseppe

“…Advanced non-clear cell renal cell carcinoma (nccRCC) has a poor prognosis and clinical data on the therapeutic options currently available, including…”
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Choosing the appropriate pharmacotherapy for breast cancer during pregnancy: what needs to be considered? by Favero, Diletta, Lapuchesky, Laura Sabina, Poggio, Francesca, Nardin, Simone, Perachino, Marta, Arecco, Luca, Scavone, Graziana, Ottonello, Silvia, Latocca, Maria Maddalena, Borea, Roberto, Puglisi, Silvia, Cosso, Maurizio, Fozza, Alessandra, Spinaci, Stefano, Lambertini, Matteo

“…Breast cancer is the most commonly diagnosed malignancy during pregnancy. Breast cancer during pregnancy is a challenging clinical condition requiring proper…”
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The Prognostic Role of Baseline Metabolic Tumor Burden and Systemic Inflammation Biomarkers in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Radium-223: A Proof of Concept Study by Bauckneht, Matteo, Rebuzzi, Sara Elena, Signori, Alessio, Donegani, Maria Isabella, Murianni, Veronica, Miceli, Alberto, Borea, Roberto, Raffa, Stefano, Damassi, Alessandra, Ponzano, Marta, Catalano, Fabio, Martelli, Valentino, Marini, Cecilia, Boccardo, Francesco, Morbelli, Silvia, Sambuceti, Gianmario, Fornarini, Giuseppe

“…Over the last years has emerged the urgent need for the identification of reliable prognostic biomarkers able to potentially identify metastatic…”
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Immunotherapy retreatment: case report, review of the literature and proposal for the definition of different scenarios by Borea, Roberto, Damassi, Alessandra, Rebuzzi, Sara Elena, Banna, Giuseppe Luigi, Murianni, Veronica, Catalano, Fabio, Martelli, Valentino, Fornarini, Giuseppe

“…Immune checkpoint inhibitors have improved the treatment landscape of different tumors and one of the emerging issues is the reintroduction of immunotherapy…”
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The Role of Cyclin-Dependent Kinases (CDK) 4/6 in the Ovarian Tissue and the Possible Effects of Their Exogenous Inhibition by Scavone, Graziana, Ottonello, Silvia, Blondeaux, Eva, Arecco, Luca, Scaruffi, Paola, Stigliani, Sara, Cardinali, Barbara, Borea, Roberto, Paudice, Michele, Vellone, Valerio G., Condorelli, Margherita, Demeestere, Isabelle, Lambertini, Matteo

“…The combination of cyclin-dependent kinase (CDK) 4/6 inhibitors with endocrine therapy is the standard treatment for patients with HR+/HER2− advanced breast…”
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VISTA: A Promising Target for Cancer Immunotherapy? by Tagliamento, Marco, Agostinetto, Elisa, Borea, Roberto, Brandão, Mariana, Poggio, Francesca, Addeo, Alfredo, Lambertini, Matteo

“…Agents targeting the B7 family co-inhibitory receptors cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD-1), or its ligand…”
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Practices and views about palliative care at the end of life: A survey of oncologists from the Italian region of Liguria by Giannubilo, Irene, Battistuzzi, Linda, Ruelle, Tommaso, Poggio, Francesca Benedetta, Buzzatti, Giulia, D'Alonzo, Alessia, Della Rovere, Federica, Molinelli, Chiara, Razeti, Maria Grazia, Nardin, Simone, Arecco, Luca, Perachino, Marta, Favero, Diletta, Borea, Roberto, Pronzato, Paolo, Del Mastro, Lucia, Vecchio, Stefania, Bighin, Claudia

“…We conducted an online survey to investigate oncologists' clinical practices and views on palliative care at the end of life in the Italian region of Liguria…”
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Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors by Fisher, Jonathan, Sharma, Roshan, Don, Dilu Wisidagamage, Barisa, Marta, Hurtado, Marina Olle, Abramowski, Pierre, Porter, Lucy, Day, William, Borea, Roberto, Inglott, Sarah, Anderson, John, Pe'er, Dana

“…Despite the benefits of chimeric antigen receptor (CAR)-T cell therapies against lymphoid malignancies, responses in solid tumors have been more limited and…”
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Durable Response after Immunotherapy Discontinuation for Delayed and Severe Immune-related Adverse Event: A Case Report by Pesola, Guido, Murianni, Veronica, Rebuzzi, Sara Elena, Banna, Giuseppe Luigi, Cerbone, Luigi, Catalano, Fabio, Borea, Roberto, Gandini, Annalice, Cremante, Malvina, Puglisi, Silvia, Trovato, Francesco, Fornarini, Giuseppe

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Durable response after immunotherapy discontinuation for delayed and severe immune-related adverse events: a case report

“…Recent studies have shown that immune-related adverse events (irAEs), occurring even after the discontinuation of immune checkpoint inhibitors (ICIs), may be…”
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Clinical Significance of Germline Pathogenic Variants among 51 Cancer Predisposition Genes in an Unselected Cohort of Italian Pancreatic Cancer Patients by Puccini, Alberto, Ponzano, Marta, Dalmasso, Bruna, Vanni, Irene, Gandini, Annalice, Puglisi, Silvia, Borea, Roberto, Cremante, Malvina, Bruno, William, Andreotti, Virginia, Allavena, Eleonora, Martelli, Valentino, Catalano, Fabio, Grassi, Massimiliano, Iaia, Maria Laura, Pirrone, Chiara, Pastorino, Alessandro, Fornarini, Giuseppe, Sciallero, Stefania, Ghiorzo, Paola, Pastorino, Lorenza

“…Multigene germline panel testing is recommended for Pancreatic Cancer (PC) patients; however, for non-BRCA1/2 genes, the clinical utility is unclear. A…”
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