Search Results - "Borden, K.L.B."

RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth by Romeo, Y, Moreau, J, Zindy, P-J, Saba-El-Leil, M, Lavoie, G, Dandachi, F, Baptissart, M, Borden, K L B, Meloche, S, Roux, P P

“…The Ras/mitogen-activated protein kinase (MAPK) signalling cascade regulates various biological functions, including cell growth, proliferation and survival…”
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The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia by Hariri, F, Arguello, M, Volpon, L, Culjkovic-Kraljacic, B, Nielsen, T H, Hiscott, J, Mann, K K, Borden, K L B

“…The eukaryotic translation initiation factor eIF4E is a potent oncogene elevated in many cancers, including the M4 and M5 subtypes of acute myeloid leukemia…”
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An antiviral disulfide compound blocks interaction between arenavirus Z protein and cellular promyelocytic leukemia protein by García, C.C., Topisirovic, I., Djavani, M., Borden, K.L.B., Damonte, E.B., Salvato, M.S.

“…The promyelocytic leukemia protein (PML) forms nuclear bodies (NB) that can be redistributed by virus infection. In particular, lymphocytic choriomeningitis…”
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Finding a role for PML in APL pathogenesis: a critical assessment of potential PML activities by Strudwick, S, Borden, K L B

“…In normal mammalian cells the promyelocytic leukemia protein (PML) is primarily localized in multiprotein nuclear complexes called PML nuclear bodies. However,…”
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Two mutant binding sites of the activating transcription factor region within the E2A promoter of adenovirus exist in a novel conformation by Borden, K L

“…The solution conformations of two mutants of the ATF (activating transcription factor) binding site within the E2A promoter of adenovirus have been determined…”
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