Search Results - "Borchardt, Erin K."

Regulation and Function of RNA Pseudouridylation in Human Cells by Borchardt, Erin K, Martinez, Nicole M, Gilbert, Wendy V

“…Recent advances in pseudouridine detection reveal a complex pseudouridine landscape that includes messenger RNA and diverse classes of noncoding RNA in human…”
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Optical Control of CRISPR/Cas9 Gene Editing by Hemphill, James, Borchardt, Erin K, Brown, Kalyn, Asokan, Aravind, Deiters, Alexander

“…The CRISPR/Cas9 system has emerged as an important tool in biomedical research for a wide range of applications, with significant potential for genome…”
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Second Messenger Cyclic Di-GMP Regulates Clostridium difficile Toxin Production by Controlling Expression of sigD by McKee, Robert W, Mangalea, Mihnea R, Purcell, Erin B, Borchardt, Erin K, Tamayo, Rita

“…The Gram-positive obligate anaerobe Clostridium difficile causes potentially fatal intestinal diseases. How this organism regulates virulence gene expression…”
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Tissue-Dependent Expression and Translation of Circular RNAs with Recombinant AAV Vectors In Vivo by Meganck, Rita M., Borchardt, Erin K., Castellanos Rivera, Ruth M., Scalabrino, Miranda L., Wilusz, Jeremy E., Marzluff, William F., Asokan, Aravind

“…Circular RNAs (circRNAs) are long-lived, covalently closed RNAs that are abundantly expressed and evolutionarily conserved across eukaryotes. Possible…”
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Inducing circular RNA formation using the CRISPR endoribonuclease Csy4 by Borchardt, Erin K, Meganck, Rita M, Vincent, Heather A, Ball, Christopher B, Ramos, Silvia B V, Moorman, Nathaniel J, Marzluff, William F, Asokan, Aravind

“…Circular RNAs (circRNAs) are highly stable, covalently closed RNAs that are regulated in a spatiotemporal manner and whose functions are largely unknown. These…”
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Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4 by Borchardt, Erin K, Vandoros, Leonidas A, Huang, Michael, Lackey, Patrick E, Marzluff, William F, Asokan, Aravind

“…The bacterial CRISPR endoribonuclease Csy4 has recently been described as a potential RNA processing tool. Csy4 recognizes substrate RNA through a specific…”
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