Search Results - "Bootman, M"

Calcium - a life and death signal by Berridge, Michael J, Bootman, Martin D, Lipp, Peter

“…One of the most versatile and universal signaling agents in the human body is the calcium ion, Ca2+, but the way in which it acts during cell birth, life and…”
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Intra-axonal calcium changes after axotomy in wild-type and slow Wallerian degeneration axons by Adalbert, R, Morreale, G, Paizs, M, Conforti, L, Walker, S.A, Roderick, H.L, Bootman, M.D, Siklós, L, Coleman, M.P

“…Highlights ► No link between Ca2+ distribution and Wallerian degeneration at time points studied. ► Schmidt–Lanterman clefts in WldS show slightly lower basal…”
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Unifying principles of calcium wave propagation — Insights from a three-dimensional model for atrial myocytes by Thul, R., Rietdorf, K., Bootman, M.D., Coombes, S.

“…Atrial myocytes in a number of species lack transverse tubules. As a consequence the intracellular calcium signals occurring during each heartbeat exhibit…”
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The versatility and universality of calcium signalling by Berridge, Michael J, Lipp, Peter, Bootman, Martin D

“…The universality of calcium as an intracellular messenger depends on its enormous versatility. Cells have a calcium signalling toolkit with many components…”
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Imaging the hierarchical Ca2+ signalling system in HeLa cells by Bootman, M, Niggli, E, Berridge, M, Lipp, P

“…1. Confocal microscopy was used to investigate hormone-induced subcellular Ca2+ release signals from the endoplasmic reticulum (ER) in a prototype…”
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Calcium signalling by Berridge, Michael, Lipp, Peter, Bootman, Martin

“…Cellular signalling mechanisms are designed to transmit information from the cell surface membrane to specific targets within the cell. Often, the information…”
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Calcium in the heart: when it's good, it's very very good, but when it's bad, it's horrid by Roderick, H L, Higazi, D R, Smyrnias, I, Fearnley, C, Harzheim, D, Bootman, M D

“…Ca(2+) increases in the heart control both contraction and transcription. To accommodate a short-term increased cardiovascular demand, neurohormonal modulators…”
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Signal transduction. The calcium entry pas de deux by Berridge, M J, Lipp, P, Bootman, M D

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Nuclear calcium signalling by Bootman, M D, Thomas, D, Tovey, S C, Berridge, M J, Lipp, P

“…The topic of nuclear Ca2+ signalling is beset by discrepant observations of substantial nuclear/cytoplasmic gradients. The reasons why some labs have recorded…”
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Defective chemoattractant-induced calcium signalling in S100A9 null neutrophils by McNeill, E, Conway, S.J, Roderick, H.L, Bootman, M.D, Hogg, N

“…Abstract The S100 family member S100A9 and its heterodimeric partner, S100A8, are cytosolic Ca2+ binding proteins abundantly expressed in neutrophils. To…”
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The elemental principles of calcium signaling by Bootman, Martin D., Berridge, Michael J.

“…Ca super(2+) is a ubiquitous intracellular signaling molecule controlling a wide array of cellular processes, including secretion, contraction, and cell…”
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FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments by Ridley, S H, Ktistakis, N, Davidson, K, Anderson, K E, Manifava, M, Ellson, C D, Lipp, P, Bootman, M, Coadwell, J, Nazarian, A, Erdjument-Bromage, H, Tempst, P, Cooper, M A, Thuring, J W, Lim, Z Y, Holmes, A B, Stephens, L R, Hawkins, P T

“…FENS-1 and DFCP1 are recently discovered proteins containing one or two FYVE-domains respectively. We show that the FYVE domains in these proteins can bind…”
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Bi-directional signalling from the InsP3 receptor: regulation by calcium and accessory factors by Roderick, H L, Bootman, M D

“…Calcium is a pleiotropic messenger controlling a diverse array of intracellular events from fertilization to cell death. One of the main mechanisms by which…”
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The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor by Bootman, M D, Taylor, C W, Berridge, M J

“…The thiol reagent, thimerosal, has been shown to cause an increase in intracellular Ca2+ concentration ([Ca2+]i) in several cell types, and to cause Ca2+…”
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Cooking with calcium: the recipes for composing global signals from elementary events by Bootman, M D, Berridge, M J, Lipp, P

“…Recent studies have suggested that global intracellular Ca2+ signals arise from the summation and coordination of subcellular elementary release events (e.g.,…”
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A comparison of fluorescent Ca2+indicator properties and their use in measuring elementary and global Ca2+signals by Thomas, D., Tovey, S.C., Collins, T.J., Bootman, M.D., Berridge, M.J., Lipp, P.

“…Quantifying the magnitude of Ca2+signals from changes in the emission of fluorescent indicators relies on assumptions about the indicator behaviour in situ…”
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The JAK3 inhibitor WHI‐P154 prevents PDGF‐evoked process outgrowth in human neural precursor cells by Richards, G. R., Smith, A. J., Cuddon, P., Ma, Q. P., Leveridge, M., Kerby, J., Roderick, H. L., Bootman, M. D., Simpson, P. B.

“…The prospect of manipulating endogenous neural stem cells to replace damaged tissue and correct functional deficits offers a novel mechanism for treating a…”
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Calcium signalling—an overview by Bootman, Martin D, Collins, Tony J, Peppiatt, Claire M, Prothero, Larissa S, MacKenzie, Lauren, De Smet, Patrick, Travers, Marianne, Tovey, Stephen C, Seo, Jeong T, Berridge, Michael J, Ciccolini, Francesca, Lipp, Peter

“…Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription (see Mellström and…”
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Ca2+ entry into PC12 cells initiated by ryanodine receptors or inositol 1,4,5-trisphosphate receptors by Bennett, D L, Bootman, M D, Berridge, M J, Cheek, T R

“…Capacitative Ca2+ entry (CCE) is a universal mechanism for refilling intracellular Ca2+ stores in electrically non-excitable cells. The situation in excitable…”
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Expression and Function of Ryanodine Receptors in Nonexcitable Cells by Bennett, D L, Cheek, T R, Berridge, M J, De Smedt, H, Parys, J B, Missiaen, L, Bootman, M D

“…We have used reverse transcriptase-polymerase chain reaction to investigate the expression of ryanodine receptors in several excitable and nonexcitable cell…”
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