Search Results - "Boothroyd, J C"

Polymorphic Secreted Kinases Are Key Virulence Factors in Toxoplasmosis by Saeij, J. P. J., Boyle, J. P., Coller, S., Taylor, S., Sibley, L. D., Brooke-Powell, E. T., Ajioka, J. W., Boothroyd, J. C.

“…The majority of known Toxoplasma gondii isolates from Europe and North America belong to three clonal lines that differ dramatically in their virulence,…”
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Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue by Boothroyd, J. C, Saeij, J. P. J, Coller, S, Boyle, J. P, Jerome, M. E, White, M. W

“…Toxoplasma gondii, an obligate intracellular parasite of the phylum Apicomplexa, can cause severe disease in humans with an immature or suppressed immune…”
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Infection with Toxoplasma gondii Bradyzoites Has a Diminished Impact on Host Transcript Levels Relative to Tachyzoite Infection by Fouts, A.E, Boothroyd, J.C

“…Toxoplasma gondii, an intracellular pathogen, has the potential to infect nearly every warm-blooded animal but rarely causes morbidity. The ability for the…”
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Lytic Cycle of Toxoplasma gondii by BLACK, Michael W, BOOTHROYD, John C

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Success and Virulence in Toxoplasma as the Result of Sexual Recombination between Two Distinct Ancestries by Grigg, Michael E., Bonnefoy, Serge, Hehl, Adrian B., Suzuki, Yasuhiro, Boothroyd, John C.

“…Toxoplasma gondii is a common human pathogen causing serious, even fatal, disease in the developing fetus and in immunocompromised patients. Despite its…”
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An unusual genotype of Toxoplasma gondii is common in California sea otters ( Enhydra lutris nereis) and is a cause of mortality by Miller, M.A, Grigg, M.E, Kreuder, C, James, E.R, Melli, A.C, Crosbie, P.R, Jessup, D.A, Boothroyd, J.C, Brownstein, D, Conrad, P.A

“…Toxoplasma gondii-associated meningoencephalitis is a significant disease of California sea otters ( Enhydra lutris nereis), responsible for 16% of total…”
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Rapid identification of virulent type I strains of the protozoan pathogen Toxoplasma gondii by pcr-restriction fragment length polymorphism analysis at the B1 gene by GRIGG, Michael E, BOOTHROYD, John C

“…Sequence analysis at the 35-fold-repetitive B1 locus identified three restriction sites capable of discriminating type I (mouse-virulent) from type II or III…”
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Ionophore-Resistant Mutants of Toxoplasma gondii Reveal Host Cell Permeabilization as an Early Event in Egress by Black, Michael W., Arrizabalaga, Gustavo, Boothroyd, John C.

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Use of Toxoplasma gondii expressing beta-galactosidase for colorimetric assessment of drug activity in vitro by MCFADDEN, D. C, SEEBER, F, BOOTHROYD, J. C

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Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction by BURG, J. L, GROVER, C. M, POULETTY, P, BOOTHROYD, J. C

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Transient Transfection and Expression in the Obligate Intracellular Parasite Toxoplasma gondii by Soldati, Dominique, Boothroyd, John C.

“…Toxoplasma gondii is a protozoan pathogen that produces severe disease in humans and animals. This obligate intracellular parasite provides an excellent model…”
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Virulent strains of Toxoplasma gondii comprise a single clonal lineage by Sibley, L. David, Boothroyd, John C

“…The protozoan Toxoplasma gondii is a prevalent parasite in wild and domestic animals worldwide, being transmitted through the food chain by carnivorous feeding…”
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gracilarioids in South Africa: long-term monitoring of a declining resource by Rothman, M. D, Anderson, R. J, Boothroyd, C. J. T, Kemp, F. A, Bolton, J. J

“…In South Africa, gracilarioid red algae have been collected as wash-up to be dried and sold for agar extraction for at least 50 years. Despite much research,…”
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Gene Replacement in Toxoplasma gondii with Chloramphenicol Acetyltransferase as Selectable Marker by Kim, Kami, Soldati, Dominique, Boothroyd, John C.

“…A system for stable transformation of Toxoplasma gondii tachyzoites was developed that exploited the susceptibility of Toxoplasma to chloramphenicol…”
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surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1 by Manger, I.D, Hehl, A.B, Boothroyd, J.C

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Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid by GROVER, C. M, THULLIEZ, P, REMINGTON, J. S, BOOTHROYD, J. C

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Expressed Sequence Tag Analysis of the Bradyzoite Stage of Toxoplasma gondii: Identification of Developmentally Regulated Genes by MANGER, I. D, HEHL, A, PARMLEY, S, SIBLEY, L. D, MARRA, M, HILLIER, L, WATERSTON, R, BOOTHROYD, J. C

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Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii by Burg, JL, Perelman, D, Kasper, LH, Ware, PL, Boothroyd, JC

“…The complete sequence of P30, the major surface Ag of the protozoan parasite, Toxoplasma gondii, has been deduced through the cloning and analysis of its gene…”
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Generation of a Restriction Fragment Length Polymorphism Linkage Map for Toxoplasma gondii by Sibley, L. D, LeBlanc, A. J, Pfefferkorn, E. R, Boothroyd, J. C

“…We have constructed a genetic linkage map for the parasitic protozoan, Toxoplasma gondii, using randomly selected low copy number DNA markers that define…”
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Protection of mice from fatal Toxoplasma gondii infection by immunization with p30 antigen in liposomes by Bulow, R, Boothroyd, JC

“…Using liposomes as adjuvant, a purified membrane Ag from Toxoplasma gondii (p30) has been tested for its protective effect in mice. Immunization with p30 in…”
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