Search Results - "Booth, Jessica R"

Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein by Chen, Xiangrong, Ali, Yusuf I, Fisher, Charlotte El, Arribas-Bosacoma, Raquel, Rajasekaran, Mohan B, Williams, Gareth, Walker, Sarah, Booth, Jessica R, Hudson, Jessica Jr, Roe, S Mark, Pearl, Laurence H, Ward, Simon E, Pearl, Frances Mg, Oliver, Antony W

“…BLM (Bloom syndrome protein) is a RECQ-family helicase involved in the dissolution of complex DNA structures and repair intermediates. Synthetic lethality…”
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Abstract 2907: Targeting the epigenetic regulator KAT2a in cancer by Gunnell, Andrea, Downs, Jessica, Pennicott, Lewis, Osborn, Kay, Grand, Darren Le, Duffell, Katie, Patel, Hitesh, Hudson, Jessica, Booth, Jessica R., Ward, Simon

“…Gene expression frequently requires the dynamic remodelling of the chromatin architecture to orchestrate the assembly of transcriptional protein complexes at…”
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