Search Results - "Boonen, M."

Functional analysis of genetic variants in the high-risk breast cancer susceptibility gene PALB2 by Boonen, Rick A. C. M., Rodrigue, Amélie, Stoepker, Chantal, Wiegant, Wouter W., Vroling, Bas, Sharma, Milan, Rother, Magdalena B., Celosse, Nandi, Vreeswijk, Maaike P. G., Couch, Fergus, Simard, Jacques, Devilee, Peter, Masson, Jean-Yves, van Attikum, Haico

“…Heterozygous carriers of germ-line loss-of-function variants in the DNA repair gene PALB2 are at a highly increased lifetime risk for developing breast cancer…”
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Neuronal activity enhances tau propagation and tau pathology in vivo by Wu, Jessica W, Hussaini, S Abid, Bastille, Isle M, Rodriguez, Gustavo A, Mrejeru, Ana, Rilett, Kelly, Sanders, David W, Cook, Casey, Fu, Hongjun, Boonen, Rick A C M, Herman, Mathieu, Nahmani, Eden, Emrani, Sheina, Figueroa, Y Helen, Diamond, Marc I, Clelland, Catherine L, Wray, Selina, Duff, Karen E

“…The authors show that tau can be released by neurons and transferred to other neurons via the extracellular space. Moreover, they show that enhancing neuronal…”
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Effectiveness and costs of specialised physiotherapy given via ParkinsonNet: a retrospective analysis of medical claims data by Ypinga, Jan H L, de Vries, Nienke M, Boonen, Lieke H H M, Koolman, Xander, Munneke, Marten, Zwinderman, Aeilko H, Bloem, Bastiaan R

“…Parkinson's disease is a complex condition that is best managed by specialised professionals. Trials show that specialised allied health interventions are…”
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Tinker, tailor, deliberate. An ethnographic inquiry into the institutionalized practice of bar-coded medication administration technology by nurses by Boonen, M.J.M.H., Vosman, Frans J.H., Niemeijer, Alistair R.

“…Explore the practice of nurses working with bar-coded medication administration technology, to gain insight in the impact it has on their work. The widespread…”
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Essential environmental cues from the satellite cell niche: optimizing proliferation and differentiation by Boonen, K J M, Rosaria-Chak, K Y, Baaijens, F P T, van der Schaft, D W J, Post, M J

“…The use of muscle progenitor cells (MPCs) for regenerative medicine has been severely compromised by their decreased proliferative and differentiative capacity…”
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The role of SLX4 and its associated nucleases in DNA interstrand crosslink repair by Hoogenboom, Wouter S, Boonen, Rick A C M, Knipscheer, Puck

“…Abstract A key step in the Fanconi anemia pathway of DNA interstrand crosslink (ICL) repair is the ICL unhooking by dual endonucleolytic incisions. SLX4/FANCP…”
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Identification of novel 3D-genome altering and complex structural variants underlying retinitis pigmentosa type 17 through a multistep and high-throughput approach by de Bruijn, Suzanne E., Panneman, Daan M., Weisschuh, Nicole, Cadena, Elizabeth L., Boonen, Erica G. M., Holtes, Lara K., Astuti, Galuh D. N., Cremers, Frans P. M., Leijsten, Nico, Corominas, Jordi, Gilissen, Christian, Skowronska, Anna, Woodley, Jessica, Beggs, Andrew D., Toulis, Vasileios, Chen, Di, Cheetham, Michael E., Hardcastle, Alison J., McLaren, Terri L., Lamey, Tina M., Thompson, Jennifer A., Chen, Fred K., de Roach, John N., Urwin, Isabella R., Sullivan, Lori S., Roosing, Susanne

“…Introduction Autosomal dominant retinitis pigmentosa type 17 (adRP, type RP17) is caused by complex structural variants (SVs) affecting a locus on chromosome…”
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Advanced maturation by electrical stimulation: Differences in response between C2C12 and primary muscle progenitor cells by Langelaan, Marloes L. P., Boonen, Kristel J. M., Rosaria-Chak, Kang Yuen, van der Schaft, Daisy W. J., Post, Mark J., Baaijens, Frank P. T.

“…Skeletal muscle tissue engineering still does not result in the desired functional properties and texture as preferred for regenerative medicine and meat…”
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The evolving role of investigative toxicology in the pharmaceutical industry by Pognan, Francois, Beilmann, Mario, Boonen, Harrie C. M., Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Oinonen, Teija, Roth, Adrian, Steger-Hartmann, Thomas, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J., Newham, Peter

“…For decades, preclinical toxicology was essentially a descriptive discipline in which treatment-related effects were carefully reported and used as a basis to…”
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Effects of a combined mechanical stimulation protocol: Value for skeletal muscle tissue engineering by Boonen, Kristel J.M, Langelaan, Marloes L.P, Polak, Roderick B, van der Schaft, Daisy W.J, Baaijens, Frank P.T, Post, Mark J

“…Abstract Skeletal muscle is an appealing topic for tissue engineering because of its variety in applications for regenerative medicine, in vitro physiological…”
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Functional Characterization of PALB2 Variants of Uncertain Significance: Toward Cancer Risk and Therapy Response Prediction by Boonen, Rick A. C. M., Vreeswijk, Maaike P. G., van Attikum, Haico

“…In recent years it has become clear that pathogenic variants in PALB2 are associated with a high risk for breast, ovarian and pancreatic cancer. However, the…”
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Papineau-irrigation technique: an alternative treatment of fracture-related infectious soft tissue defects by Boonen, M, Ginckels, L, Tuerlinckx, G, Lammens, J

“…The original Papineau technique described satisfactory results in treating infection-related pseudarthrosis and chronic osteomyelitis with chronic draining…”
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COMPACT HYPERSPECTRAL IMAGING SYSTEM (COSI) FOR SMALL REMOTELY PILOTED AIRCRAFT SYSTEMS (RPAS) – SYSTEM OVERVIEW AND FIRST PERFORMANCE EVALUATION RESULTS by Sima, A. A., Baeck, P., Nuyts, D., Delalieux, S., Livens, S., Blommaert, J., Delauré, B., Boonen, M.

“…This paper gives an overview of the new COmpact hyperSpectral Imaging (COSI) system recently developed at the Flemish Institute for Technological Research…”
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Engineering skeletal muscle tissues from murine myoblast progenitor cells and application of electrical stimulation by van der Schaft, Daisy W J, van Spreeuwel, Ariane C C, Boonen, Kristel J M, Langelaan, Marloes L P, Bouten, Carlijn V C, Baaijens, Frank P T

“…Engineered muscle tissues can be used for several different purposes, which include the production of tissues for use as a disease model in vitro, e.g. to…”
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Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs by Boonen, Harrie C. M., Moesgaard, Sophia G., Birck, Malene M., Christoffersen, Berit Ø., Cirera, Susanna, Heegaard, Peter M. H., Højbøge, Tina Rødgaard, Jensen, Lars J., Mortensen, Alan, Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, Jiaowei, Lykkesfeldt, Jens

“…The Göttingen minipig model of obesity is used in pre-clinical research to predict clinical outcome of new treatments for metabolic diseases. However,…”
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Switching health insurers: the role of price, quality and consumer information search by Boonen, Lieke H. H. M., Laske-Aldershof, Trea, Schut, Frederik T.

“…We examine the impact of price, service quality and information search on people's propensity to switch health insurers in the competitive Dutch health…”
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Evaluation process of new raspberry and blackberry cultivars for the Belgian market at pcfruit by Boonen, M., Spruyt, C., Bylemans, D.

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Urine flow cytometry as a primary screening method to exclude urinary tract infections by Boonen, K. J. M., Koldewijn, E. L., Arents, N. L. A., Raaymakers, P. A. M., Scharnhorst, V.

“…Purpose To exclude urinary tract infections, culture is the gold standard method, although it is time consuming and costly. Current strategies using dipstick…”
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Meet the new meat: tissue engineered skeletal muscle by Langelaan, Marloes L.P., Boonen, Kristel J.M., Polak, Roderick B., Baaijens, Frank P.T., Post, Mark J., van der Schaft, Daisy W.J.

“…Contemporary large-scale farming and transportation of livestock brings along a high risk of infectious animal diseases and environmental burden through…”
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The muscle stem cell niche: regulation of satellite cells during regeneration by Boonen, Kristel J M, Post, Mark J

“…Satellite cells are considered to be adult skeletal muscle stem cells. Their ability to regenerate large muscle defects is highly dependent on their specific…”
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