Search Results - "Boon, Wouter P. C"

Expert perspectives on the introduction of Triple Artemisinin-based Combination Therapies (TACTs) in Southeast Asia: a Delphi study by de Haan, Freek, Boon, Wouter P C, Amaratunga, Chanaki, Dondorp, Arjen M

“…Triple Artemisinin-based Combination Therapies (TACTs) are being developed as a response to artemisinin and partner drug resistance in Southeast Asia. However,…”
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A standardised framework to identify optimal animal models for efficacy assessment in drug development by Ferreira, Guilherme S, Veening-Griffioen, Désirée H, Boon, Wouter P C, Moors, Ellen H M, Gispen-de Wied, Christine C, Schellekens, Huub, van Meer, Peter J K

“…Poor translation of efficacy data derived from animal models can lead to clinical trials unlikely to benefit patients-or even put them at risk-and is a…”
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To what extent are the antimalarial markets in African countries ready for a transition to triple artemisinin-based combination therapies? by de Haan, Freek, Bolarinwa, Oladimeji Akeem, Guissou, Rosemonde, Tou, Fatoumata, Tindana, Paulina, Boon, Wouter P C, Moors, Ellen H M, Cheah, Phaik Yeong, Dhorda, Mehul, Dondorp, Arjen M, Ouedraogo, Jean Bosco, Mokuolu, Olugbenga A, Amaratunga, Chanaki

“…Triple artemisinin-based combination therapies (TACTs) are being developed as a response to artemisinin and partner drug resistance in the treatment of…”
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Exploring the feasibility of introducing triple artemisinin-based combination therapy in the malaria treatment policy in Vietnam by Cao, Van Anh Thi, Nguyen, Thieu Quang, Le Quyen, Duong, Boon, Wouter P. C, Moors, Ellen H. M, Dondorp, Arjen M, de Haan, Freek, Amaratunga, Chanaki

“…Abstract Background This study investigates the processes regarding changing malaria treatment policies in Vietnam. Moreover, it explores the feasibility of…”
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The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso by Guissou, Rosemonde M, Amaratunga, Chanaki, de Haan, Freek, Tou, Fatoumata, Cheah, Phaik Yeong, Yerbanga, R Serge, Moors, Ellen H M, Dhorda, Mehul, Tindana, Paulina, Boon, Wouter P C, Dondorp, Arjen M, Ouédraogo, Jean Bosco

“…Widespread artemisinin resistance in Africa could be catastrophic when drawing parallels with the failure of chloroquine in the 1970s and 1980s. This article…”
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Strategies for deploying triple artemisinin-based combination therapy in the Greater Mekong Subregion by de Haan, Freek, Amaratunga, Chanaki, Thi, Van Anh Cao, Orng, Long Heng, Vonglokham, Manithong, Quang, Thieu Nguyen, Lek, Dysoley, Boon, Wouter P. C, Dondorp, Arjen M, Moors, Ellen H. M

“…Abstract Background This is a qualitative study to identify implementation challenges for deploying triple artemisinin-based combination therapy (TACT) in the…”
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Exploring dynamics and strategies of niche protection by Boon, Wouter P.C., Moors, Ellen H.M., Meijer, Albert J.

“…•We study dynamics of protection in different phases of niche development.•Niche protection is explored in HIV and pandemic influenza cases.•Interactions…”
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Correction: A standardised framework to identify optimal animal models for efficacy assessment in drug development by Ferreira, Guilherme S, Veening-Griffioen, Désirée H, Boon, Wouter P C, Moors, Ellen H M, Gispen-de Wied, Christine C, Schellekens, Huub, van Meer, Peter J K

“…[This corrects the article DOI: 10.1371/journal.pone.0218014.]…”
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Demand articulation in emerging technologies: Intermediary user organisations as co-producers? by Boon, Wouter P.C., Moors, Ellen H.M., Kuhlmann, Stefan, Smits, Ruud E.H.M.

“…User involvement is assumed to be beneficial to innovation processes. Intermediary user organisations contribute to articulating societal demands for…”
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Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs by Ferreira, Guilherme S., Dijkstra, Francis M., Veening-Griffioen, Désirée H., Boon, Wouter P. C., Schellekens, Huub, Moors, Ellen H. M., van Meer, Peter J. K., Stuurman, Frederik E., van Gerven, Joop M. A.

“…The primary purpose of this study was to assess the translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for…”
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Stakeholder interaction within research consortia on emerging technologies: Learning how and what? by Roelofsen, Anneloes, Boon, Wouter P.C., Kloet, Roy R., Broerse, Jacqueline E.W.

“…▶ Within the Dutch Ecogenomics Consortium, two multi-stakeholder dialogues were conducted. ▶ We analyze the learning that took place during these dialogue…”
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Collective institutional work: the case of Airbnb in Amsterdam, London and New York by Boon, Wouter P. C., Spruit, Kristy, Frenken, Koen

“…Given that online platforms disrupt established industries and challenge existing institutions, they can only be successful if their innovation becomes both…”
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Levelling the Translational Gap for Animal to Human Efficacy Data by Ferreira, Guilherme S, Veening-Griffioen, Désirée H, Boon, Wouter P C, Moors, Ellen H M, van Meer, Peter J K

“…Reports of a reproducibility crisis combined with a high attrition rate in the pharmaceutical industry have put animal research increasingly under scrutiny in…”
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Preferred Islet Delivery Device Characteristics and Implantation Strategies of Patients With Type 1 Diabetes by Tol, Maarten C., de Bont, Denise F. A., Boon, Wouter P. C., de Koning, Eelco J. P., van Apeldoorn, Aart A.

“…Islet delivery devices (IDDs) offer potential benefits for islet transplantation and stem cell-based replacement in type 1 diabetes. Little is known about…”
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Knowledge co-production in protective spaces: case studies of two climate adaptation projects by Boon, Wouter P. C., Hessels, Laurens K., Horlings, Edwin

“…Knowledge co-production, a mode of research including contributions both from academic and non-academic actors, is a promising approach for climate adaptation…”
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A Research Pathway Model for evaluating the implementation of practice-based research: The case of self-management health innovations by van Beest, Wilke, Boon, Wouter P C, Andriessen, Daan, Pol, Harald, van der Veen, Gerrita, Moors, Ellen H M

“…Abstract This study explores the evaluation of research pathways of self-management health innovations from discovery to implementation in the context of…”
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Tradition, not science, is the basis of animal model selection in translational and applied research by Veening-Griffioen, Désirée H, Ferreira, Guilherme S, Boon, Wouter P C, Gispen-de Wied, Christine C, Schellekens, Huub, Moors, Ellen H M, Van Meer, Peter J K

“…National and international laws and regulations exist to protect animals used for scientific purposes in translational and applied research, which includes…”
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Balancing divergence and convergence in transdisciplinary research teams by Boon, Wouter P.C., Chappin, Maryse M.H., Perenboom, Jaap

“…•We studied transdisciplinary climate adaptation projects.•Organisational embedding positively influences performance.•Active project management during the…”
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An analysis of marketing authorisation applications via the mutual recognition and decentralised procedures in Europe by Ebbers, Hans C., Langedijk, Joris, Bouvy, Jacoline C., Hoekman, Jarno, Boon, Wouter P. C., de Jong, Jean Philippe, De Bruin, Marie L.

“…Purpose The aim of this study is to provide a comprehensive overview of the outcomes of marketing authorisation applications via the mutual recognition and…”
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Implementation of artificial intelligence (AI) applications in radiology: hindering and facilitating factors by Strohm, Lea, Hehakaya, Charisma, Ranschaert, Erik R., Boon, Wouter P. C., Moors, Ellen H. M.

“…Objective The objective was to identify barriers and facilitators to the implementation of artificial intelligence (AI) applications in clinical radiology in…”
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