Search Results - "Booms, P"
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Reduction of relative centrifugal forces increases growth factor release within solid platelet-rich-fibrin (PRF)-based matrices: a proof of concept of LSCC (low speed centrifugation concept)
Published in European journal of trauma and emergency surgery (Munich : 2007) (01-06-2019)“…Purpose The present study evaluated the platelet distribution pattern and growth factor release (VEGF, TGF-β1 and EGF) within three PRF (platelet-rich-fibrin)…”
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Potential lack of “standardized” processing techniques for production of allogeneic and xenogeneic bone blocks for application in humans
Published in Acta biomaterialia (01-08-2014)“…[Display omitted] In the present study, the structure of two allogeneic and three xenogeneic bone blocks, which are used in dental and orthopedic surgery, were…”
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Platelet-rich fibrin secretome induces three dimensional angiogenic activation in vitro
Published in European cells & materials (09-04-2019)“…Different tissue engineering techniques are used to support rapid vascularisation. A novel technique is the use of platelet-rich fibrin (PRF), an autologous…”
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The molecular genetics of Marfan syndrome and related disorders
Published in Journal of Medical Genetics (01-10-2006)“…Marfan syndrome (MFS), a relatively common autosomal dominant hereditary disorder of connective tissue with prominent manifestations in the skeletal, ocular,…”
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Monocyte preseeding leads to an increased implant bed vascularization of biphasic calcium phosphate bone substitutes via vessel maturation
Published in Journal of biomedical materials research. Part A (01-12-2016)“…The present study analyzes the influence of the addition of monocytes to a biphasic bone substitute with two granule sizes (400–700 μm and 500–1000 μm). The…”
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Genetic variation in RYR1 and malignant hyperthermia phenotypes
Published in British journal of anaesthesia : BJA (01-10-2009)“…Malignant hyperthermia (MH) is associated, in the majority of cases, with mutations in RYR1, the gene encoding the skeletal muscle ryanodine receptor. Our…”
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Assessing the pathogenicity of RYR1 variants in malignant hyperthermia
Published in British journal of anaesthesia : BJA (01-04-2017)“…Missense variants in the ryanodine receptor 1 gene (RYR1) are associated with malignant hyperthermia but only a minority of these have met the criteria for use…”
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P24 Biomaterial-based tissue-like constructs for assessing effects of vismodegib on soft and hard tissue
Published in Oral oncology (01-05-2015)“…This study is the first to show the effect of vismodegib on healthy and tumour cells. Such results are vey important when considering the resection margin…”
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Small-sized granules of biphasic bone substitutes support fast implant bed vascularization
Published in Biomatter (Austin, TX) (2015)“…The present study investigated the influence of granule size of 2 biphasic bone substitutes (BoneCeramic® 400-700 μm and 500-1000 μm) on the induction of…”
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The molecular pathogenesis of the Marfan syndrome
Published in Cellular and molecular life sciences : CMLS (01-10-2001)“…The Marfan syndrome (MFS) is an autosomal dominant heritable disorder of connective tissue with highly variable clinical manifestations including aortic…”
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A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: biochemical and computational analysis
Published in Journal of molecular and cellular cardiology (01-02-2006)“…Mutations in the gene for fibrillin-1 cause Marfan syndrome (MFS), a common hereditary disorder of connective tissue. Recent findings suggest that proteolysis,…”
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Epigenetic allele silencing and variable penetrance of malignant hyperthermia susceptibility
Published in British journal of anaesthesia : BJA (01-08-2009)“…Tissue-specific monoallelic silencing of the RYR1 gene has been proposed as an explanation for variable penetrance of dominant RYR1 mutations in malignant…”
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Analysis of RYR1 Haplotype Profile in Patients with Malignant Hyperthermia
Published in Annals of human genetics (01-01-2009)“…Summary This study represents a new approach to characterising patients at risk of malignant hyperthermia (MH) through the use of a recently published method…”
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Human Genome and Diseases:¶The molecular pathogenesis of the Marfan syndrome
Published in Cellular and molecular life sciences : CMLS (01-10-2001)“…The Marfan syndrome (MFS) is an autosomal dominant heritable disorder of connective tissue with highly variable clinical manifestations including aortic…”
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Differential effect of FBN1 mutations on in vitro proteolysis of recombinant fibrillin-1 fragments
Published in Human genetics (01-09-2000)“…Mutations in the fibrillin-1 gene (FBN1) cause Marfan syndrome (MFS), an autosomal dominant disorder of connective tissue with highly variable clinical…”
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The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia
Published in Journal of neurology, neurosurgery and psychiatry (01-10-1998)“…OBJECTIVES To investigate if sequence alterations of the excitatory amino acid transporter gene EAAT2 (GLT-1) may be a contributory factor to the pathogenesis…”
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