Search Results - "Boomer, Ryan M"

Pharmacokinetics and biodistribution of novel aptamer compositions by Healy, Judith M, Lewis, Scott D, Kurz, Markus, Boomer, Ryan M, Thompson, Kristin M, Wilson, Charles, McCauley, Thomas G

“…Aptamers are highly selective nucleic acid-based drugs that are currently being developed for numerous therapeutic indications. Here, we determine plasma…”
Get full text

Conjugation to polyethylene glycol polymer promotes aptamer biodistribution to healthy and inflamed tissues by Boomer, Ryan M, Lewis, Scott D, Healy, Judith M, Kurz, Markus, Wilson, Charles, McCauley, Thomas G

“…Here, we examine biodistribution of radiolabeled aptamers and assess the relative ability of different stabilized aptamer compositions (mixed 2'-F/2'-O-Me;…”
Get more information

A novel strategy for selection of allosteric ribozymes yields RiboReporter™ sensors for caffeine and aspartame by Ferguson, Alicia, Boomer, Ryan M., Kurz, Markus, Keene, Sara C., Diener, John L., Keefe, Anthony D., Wilson, Charles, Cload, Sharon T.

“…We have utilized in vitro selection technology to develop allosteric ribozyme sensors that are specific for the small molecule analytes caffeine or aspartame…”
Get full text

ADP-Specific Sensors Enable Universal Assay of Protein Kinase Activity by Srinivasan, Jayaram, Cload, Sharon T, Hamaguchi, Nobuko, Kurz, Jeffrey, Keene, Sara, Kurz, Markus, Boomer, Ryan M, Blanchard, Jill, Epstein, David, Wilson, Charles, Diener, John L

“…Two molecular sensors that specifically recognize ADP in a background of over 100-fold molar excess of ATP are described. These sensors are nucleic-acid based…”
Get full text

Discovery, Engineering and Pre-Clinical Evaluation of an Anti-vWF A1 Domain Aptamer by Diener, John L., Lagasse, H.A. Daniel, Gilbert, Madaline, Merlino, Patricia, Killough, Jason, Marsh, H. Nicholas, Boomer, Ryan M., Fraone, Joseph M., McCauley, Thomas, Makim, Ankit, Lewis, Scott D., Cai, Larry, Hutabarat, Renta, Rottman, James B., Benedict, Claude, Fontana, David

“…Following coronary artery damage, von Willebrand Factor (vWF) multimers adhere to exposed collagen via the vWF A3 domain. Platelets passing through damaged…”
Get full text

A novel strategy for selection of allosteric ribozymes yields RiboReporter registered sensors for caffeine and aspartame by Ferguson, Alicia, Boomer, Ryan M, Kurz, Markus, Keene, Sara C, Diener, John L, Keefe, Anthony D, Wilson, Charles, Cload, Sharon T

“…We have utilized in vitro selection technology to develop allosteric ribozyme sensors that are specific for the small molecule analytes caffeine or aspartame…”
Get full text