Search Results - "Bookman, Richard J"

Research informatics and the COVID-19 pandemic: Challenges, innovations, lessons learned, and recommendations by Bookman, Richard J, Cimino, James J, Harle, Christopher A, Kost, Rhonda G, Mooney, Sean, Pfaff, Emily, Rojevsky, Svetlana, Tobin, Jonathan N, Wilcox, Adam, Tsinoremas, Nick F

“…The recipients of NIH's Clinical and Translational Science Awards (CTSA) have worked for over a decade to build informatics infrastructure in support of…”
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Prolonged increase in ciliary beat frequency after short-term purinergic stimulation in human airway epithelial cells by Lieb, Thomas, Frei, Corinne Wijkstrom, Frohock, Jeffrey I., Bookman, Richard J., Salathe, Matthias

“…Stimulation of ovine airway epithelial cells with 10 μ m ATP for 1 min at 25 °C transiently increased both cytoplasmic calcium (fura-2 epifluorescence…”
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Mode of Ca2+ action on ciliary beat frequency in single ovine airway epithelial cells by Salathe, Matthias, Bookman, Richard J.

“…We analysed the kinetics of coupling between cytoplasmic calcium ([Ca 2+ ] i ) and ciliary beat frequency (CBF) using simultaneous single cilium recording and…”
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Advancing the Research Mission in a Time of Mergers and Acquisitions by Hauptman, Paul J, Bookman, Richard J, Heinig, Stephen

“…Hauptman et al focuses on the impact of merger and acquisitions involving an academic medical center with or by a nonacademic health system. Hauptman et al…”
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Agonist-stimulated calcium decreases in ovine ciliated airway epithelial cells: role of mitochondria by Salathe, Matthias, Ivonnet, Pedro I., Lieb, Thomas, Bookman, Richard J.

“…In ovine ciliated tracheal epithelial cells, acetylcholine (ACh) activates signal transduction pathways that not only transiently increase cytoplasmic Ca 2+…”
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Regulator of G-Protein Signaling Protein 2 Modulates Purinergic Calcium and Ciliary Beat Frequency Responses in Airway Epithelia by Nlend, Marie-Christine, Bookman, Richard J, Conner, Gregory E, Salathe, Matthias

“…In ciliated airway epithelial cells, purinergic stimulation increases both intracellular calcium ([Ca(2+)](i)) and ciliary beat frequency (CBF). Because…”
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Releasable pools and the kinetics of exocytosis in adrenal chromaffin cells by Horrigan, F T, Bookman, R J

“…Using high resolution capacitance (Cm) measurement techniques, we mapped the kinetics of exocytosis evoked by brief (5-100 ms) depolarizations that activate…”
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Coupling of [Ca2+]i and ciliary beating in cultured tracheal epithelial cells by Salathe, M, Bookman, R J

“…The molecular mechanisms responsible for the regulation of ciliary beating frequency (CBF) are only partially characterized. To determine whether elevation of…”
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Gene expression profiles in microdissected neurons from human hippocampal subregions by Torres-Muñoz, Jorge E, Van Waveren, Corina, Keegan, Martha G, Bookman, Richard J, Petito, Carol K

“…Pyramidal neurons in hippocampal subregions are selectively vulnerable in certain disease states. To investigate, we tested the hypothesis that selective…”
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Toxicogenomic effects of marine brevetoxins in liver and brain of mouse by Walsh, Patrick J, Bookman, Richard J, Zaias, Julia, Mayer, Gregory D, Abraham, William, Bourdelais, Andrea J, Baden, Daniel G

“…Although the polyether brevetoxins (PbTx's) produced by Karenia brevis (the organism responsible for blooms of the Florida red tide) are known to exert their…”
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Direct measurement of exocytosis and calcium currents in single vertebrate nerve terminals by Fidler Lim, Nancy, Nowycky, Martha C, Bookman, Richard J

“…The release of neurohormone is widely thought to be exocytotic, involving Ca2(+)-dependent fusion of secretory vesicles with the plasma membrane. The…”
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What would an evidence-based tinnitus patient education program look like? Findings from a scoping review by Occa, Aurora, Morgan, Susan E., Scaglione, Tricia Lynn, Kuzbyt, Brianna, Bookman, Richard J.

“…Objective: The purpose of this project was to identify the strategies available to educate patients about tinnitus and to provide guidelines and instructions…”
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Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein by Schiweizer, Felix E, Schäfer, Theo, Tapparelli, Carlo, Grob, Marianne, Karli, Urs O, Heumann, Rolf, Thoenen, Hans, Bookman, Richard J, Burger, Max M

“…Exocytotic secretion requires the interaction and fusion of secretory vesicles with the plasma membrane. This process could be mediated by specific recognition…”
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Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein by Schweizer, Felix E, Schäfer, Theo, Tapparelli, Carlo, Grob, Marianne, Karli, Urs O, Neumann, Rolf, Thoenen, Hans, Bookman, Richard J, Burger, Max M

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Lack of nitric oxide involvement in cholinergic modulation of ovine ciliary beat frequency by Salathe, M, Lieb, T, Bookman, R J

“…Ciliary beat frequency (CBF) is regulated, at least in part, by the cytoplasmic calcium concentration ([Ca(2+)](i)). Because Ca(2+) can stimulate nitric oxide…”
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Mode of Ca 2+ action on ciliary beat frequency in single ovine airway epithelial cells by Salathe, Matthias, Bookman, Richard J.

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Growth Cone Steering by Receptor Tyrosine Phosphatase δ Defines a Distinct Class of Guidance Cue by Sun, Qi Lun, Wang, Jun, Bookman, Richard J., Bixby, John L.

“…Receptor-type tyrosine phosphatases (RPTPs) are involved in pathfinding decisions by elongating axons, but how they function in these decisions remains…”
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Regulator of G-protein singnaling protein 2 modulates purinergic calcium and ciliary beat frequency responses in airway epithelia by Nlend, Marie-Christine, Bookman, Richard J, Conner, Gregory E, Salathe, Matthias

“…In ciliated airway epithelial cells, purinergic stimulation increases both intracellular calcium ([Ca(2+)](i)) and ciliary beat frequency (CBF). Because…”
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Ca2+ Influx and Neurite Growth in Response to Purified N-Cadherin and Laminin by Bixby, John L., Grunwald, Gerald B., Bookman, Richard J.

“…The signaling mechanisms underlying neurite growth induced by cadherins and integrins are incompletely understood. In our experiments, we have examined these…”
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Ionic conductances of squid giant fiber lobe neurons by LLANO, I, BOOKMAN, R. J

“…The cell bodies of the neurons in the giant fiber lobe (GFL) of the squid stellate ganglion give rise to axons that fuse and thereby form the third-order giant…”
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