Search Results - "Boogaard, P.J."

Building scientific confidence in the development and evaluation of read-across by Patlewicz, G., Ball, N., Boogaard, P.J., Becker, R.A., Hubesch, B.

“…•Guiding principles are outlined for the development of read-across justifications.•Scientific confidence considerations are discussed for read-across…”
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Selective evaluation of potentially carcinogenic polycyclic aromatics in mineral oil by the DMSO based IP346 method by Carrillo, J.C., Boogaard, P.J.

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Ascending aorta curvature and flow displacement are associated with accelerated aortic growth at long-term follow-up: A MRI study in Marfan and thoracic aortic aneurysm patients by van Hout, M.J.P., Juffermans, J.F., Lamb, H.J., Kröner, E.S.J., van den Boogaard, P.J., Schalij, M.J., Dekkers, I.A., Scholte, A.J., Westenberg, J.J.

“…Aortic aneurysm formation is associated with increased risk of aortic dissection. Current diagnostic strategies are focused on diameter growth, the predictive…”
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The effect of alkyl substitution on Polycyclic Aromatic Hydrocarbons (PAHs) that may be present in the mineral oils on their oxidative metabolism by Wang, D., Rietjens, I.M., Boogaard, P.J.

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P06-16: Physiologically-based kinetic (PBK) modeling-facilitated reverse dosimetry to predict in vivo developmental toxicity of benzo[a]pyrene (B[a]P) in rats by Wang, D., Rietdijk, M.H., Kamelia, L., Boogaard, P.J., Rietjens, I.M.

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P06-16: Physiologically-based kinetic (PBK) modeling-facilitated reverse dosimetry to predictin vivodevelopmental toxicity of benzo[a]pyrene (B[a]P) in rats by Wang, D., Rietdijk, M.H., Kamelia, L., Boogaard, P.J., Rietjens, I.M.

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P17-17 Assessment of the intestinal absorption of higher olefins by the everted gut sac model in combination with in silicon newapproach methodologies by Shi, Q., Carrillo, J.-C., Penman, M., Manton, J., Fioravanzo, E., Powrie, R., Elcombe, C.R., Borsboom-Patel, T., Tian, Y., Shen, H., Boogaard, P.J.

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Toxicogenomics in vitro as an alternative tool for safety evaluation of petroleum substances and PAHs with regard to prenatal developmental toxicity by Tsitou, Polyxeni, Heneweer, Marjoke, Boogaard, Peter J.

“…•Toxicogenomics as tool in the assessment of prenatal developmental toxicity of petroleum products.•Heavy PAH are likely to be responsible for the…”
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Derivation of no significant risk levels for three lower acrylates: Conclusions and recommendations from an expert panel by Kirman, C.R., Boogaard, P.J., Bus, J.S., Dellarco, V.L., Shao, K., Stern, B.R., Hays, S.M.

“…A panel of toxicology, mode of action (MOA), and cancer risk assessment experts was engaged to derive no-significant-risk-levels (NSRLs) for three lower…”
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Cancer weight of evidence for three lower acrylates: Conclusions and recommendations from an expert panel by Kirman, C.R., Boogaard, P.J., Bus, J.S., Dellarco, V.L., DePass, L.R., Stern, B.R., Hays, S.M.

“…An international panel of experts was engaged to assess the cancer weight of evidence (WOE) for three lower acrylates: methyl acrylate, ethyl acrylate, and…”
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Biomarkers of benzene exposure and their interpretation for human health risk assessment by Boogaard, P.J., Arnold, S.M., Hughes, M.F., Price, P.S., Robison, S.H.

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Development of a framework for determining the appropriateness of a biomarker of exposure by Doerrer, N.G., Zelenka, M.P., Bird, M.G., Barr, D.B., Boogaard, P.J.

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Context is key—Case studies on the biological significance and role of DNA adduct data in cancer risk assessment by Boogaard, P.J., Bachman, A., Martin, E., Mauthe, R.J., Pottenger, L.H., Schoeny, R., Skare, J.A., Kim, J.

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The use of biomarkers for risk assessment: Reporting from the INTARESE/ENVIRISK Workshop in Prague by Smolders, R., Bartonova, A., Boogaard, P.J., Dusinska, M., Koppen, G., Merlo, F., Sram, R.J., Vineis, P., Schoeters, G.

“…This publication is a report on the workshop “The use of biomarkers for risk assessment” which took place in November 2007 in Prague, the Czech Republic. The…”
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Biological monitoring of exposure to benzene: a comparison between S-phenylmercapturic acid, trans,trans-muconic acid, and phenol by Boogaard, P J, van Sittert, N J

“…OBJECTIVES--Comparison of the suitability of two minor urinary metabolites of benzene, trans,trans-muconic acid (tt-MA) and S-phenylmercapturic acid (S-PMA),…”
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A proposed framework for the interpretation of biomonitoring data by Boogaard, P.J., Farmer, P.B., Holt, M., Knudsen, L.E., Money, C.D., Onyon, L., Owen, D.E., Robison, S.H., Schoeters, G., Stropp, G.D., Wilks, M.F., Will, W.

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Urinary 1-hydroxypyrene as biomarker of exposure to polycyclic aromatic hydrocarbons in workers in petrochemical industries: baseline values and dermal uptake by Boogaard, P.J., van Sittert, N.J.

“…The suitability of urinary 1-hydroxypyrene as a biomarker for the assessment of exposure to polycyclic aromatic hydrocarbons (PAH) in petrochemical industries…”
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Nephrotoxicity of halogenated alkenyl cysteine-S-conjugates by Nagelkerke, J F, Boogaard, P J

“…In 1916 a relationship was postulated between the occurrence of aplastic anaemia in cattle and the soy bean meal that they had been fed, which had been…”
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Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide (EtO) by Tates, A.D., Boogaard, P.J., Darroudi, F., Natarajan, A.T., Caubo, M.E., van Sittert, N.J.

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Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide by Tates, A D, Boogaard, P J, Darroudi, F, Natarajan, A T, Caubo, M E, van Sittert, N J

“…Peripheral blood from four groups of seven workers from a chemical manufacturing plant in The Netherlands was analyzed for hemoglobin adducts in erythrocytes…”
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