Search Results - "Bood, Mattias"
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1
Interbase-FRET binding assay for pre-microRNAs
Published in Scientific reports (30-04-2021)“…The aberrant expression of microRNAs (miRs) has been linked to several human diseases. A promising approach for targeting these anomalies is the use of…”
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2
Fluorescent nucleobase analogues for base-base FRET in nucleic acids: synthesis, photophysics and applications
Published in Beilstein journal of organic chemistry (2018)“…Förster resonance energy transfer (FRET) between a donor nucleobase analogue and an acceptor nucleobase analogue, base-base FRET, works as a spectroscopic…”
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3
Interbase FRET in RNA: from A to Z
Published in Nucleic acids research (04-11-2019)“…Abstract Interbase FRET can reveal highly detailed information about distance, orientation and dynamics in nucleic acids, complementing the existing structure…”
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4
Metabolic RNA labeling in non-engineered cells following spontaneous uptake of fluorescent nucleoside phosphate analogues
Published in Nucleic acids research (20-08-2024)“…RNA and its building blocks play central roles in biology and have become increasingly important as therapeutic agents and targets. Hence, probing and…”
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5
8-Bromination of 2,6,9-trisubstituted purines with pyridinium tribromide
Published in Tetrahedron letters (30-04-2014)“…[Display omitted] 2,6,9-Trisubstituted purines are brominated in high yields using pyridinium tribromide as the brominating reagent. This procedure works…”
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6
Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET
Published in Journal of the American Chemical Society (12-07-2017)“…Förster resonance energy transfer (FRET) using fluorescent base analogues is a powerful means of obtaining high-resolution nucleic acid structure and dynamics…”
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7
Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor
Published in Nucleic acids research (20-08-2020)“…Abstract With the central role of nucleic acids there is a need for development of fluorophores that facilitate the visualization of processes involving…”
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8
Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue
Published in Chemical science (Cambridge) (2018)“…Emissive base analogs are powerful tools for probing nucleic acids at the molecular level. Herein we describe the development and thorough characterization of…”
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Second-Generation Fluorescent Quadracyclic Adenine Analogues: Environment-Responsive Probes with Enhanced Brightness
Published in Chemistry : a European journal (02-03-2015)“…Fluorescent base analogues comprise a group of increasingly important molecules for the investigation of nucleic acid structure, dynamics, and interactions…”
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10
Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design
Published in Scientific reports (31-07-2015)“…Fluorescent base analogues (FBAs) comprise a family of increasingly important molecules for the investigation of nucleic acid structure and dynamics. We…”
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Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogueElectronic supplementary information (ESI) available. See DOI: 10.1039/c7sc05448c
Published 04-04-2018“…Emissive base analogs are powerful tools for probing nucleic acids at the molecular level. Herein we describe the development and thorough characterization of…”
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Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc05448c
Published in Chemical science (Cambridge) (01-03-2018)“…A highly fluorescent, non-perturbing, pentacyclic adenine analog was designed, synthesized, incorporated into DNA and photophysical evaluated. Emissive base…”
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13
Lighting Up DNA with the Environment‐Sensitive Bright Adenine Analogue qAN4
Published in ChemPlusChem (Weinheim, Germany) (01-02-2020)“…The fluorescent adenine analogue qAN4 was recently shown to possess promising photophysical properties, including a high brightness as a monomer. Here we…”
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