Search Results - "Bonvin, Elise"
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Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation
Published in Nature communications (02-10-2020)“…Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine…”
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Transcriptome-wide distribution and function of RNA hydroxymethylcytosine
Published in Science (American Association for the Advancement of Science) (15-01-2016)“…Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is…”
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3
Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
Published in Cancer research (Chicago, Ill.) (15-10-2009)“…How melanoma acquire a metastatic phenotype is a key issue. One possible mechanism is that metastasis is driven by microenvironment-induced switching between…”
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A Phosphatidylinositol 3-Kinase–Pax3 Axis Regulates Brn-2 Expression in Melanoma
Published in Molecular and Cellular Biology (01-11-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Congenital tracheal malformation in cystic fibrosis transmembrane conductance regulator-deficient mice
Published in The Journal of physiology (01-07-2008)“…In cystic fibrosis (CF) patients, the major alteration in pulmonary function is due to peripheral airway obstruction. In the present study, we investigated the…”
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Phosphorylation of BRN2 Modulates Its Interaction with the Pax3 Promoter To Control Melanocyte Migration and Proliferation
Published in Molecular and Cellular Biology (01-04-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
New Method for Efficient siRNA Delivery in Retina Explants: Reverse Magnetofection
Published in Bioconjugate chemistry (16-06-2021)“…The prevalence of retinal disorders associated with visual impairment and blindness is increasing worldwide, while most of them remain without effective…”
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TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression
Published in Cancer research (Chicago, Ill.) (01-02-2019)“…Although numerous epigenetic aberrancies accumulate in melanoma, their contribution to initiation and progression remain unclear. The epigenetic mark…”
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Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis
Published in The journal of histochemistry and cytochemistry (01-03-2021)“…The mouse line carrying the Tg(Tyr-NRAS*Q61K)1Bee transgene is widely used to model in vivo NRAS-driven melanomagenesis. Although the pathological features of…”
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Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion
Published in Journal of investigative dermatology (01-07-2022)“…Phenotypic plasticity drives cancer progression, impacts treatment response, and is a major driver of therapeutic resistance. In melanoma, a regulatory axis…”
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Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: Potential mechanism for excessive IL-8 expression
Published in The international journal of biochemistry & cell biology (2008)“…Cystic fibrosis (CF) is a lethal disease caused by defective function of the cftr gene product, the CF transmembrane conductance regulator (CFTR) that leads to…”
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Cystic Fibrosis Transmembrane Conductance Regulator Controls Lung Proteasomal Degradation and Nuclear Factor-κB Activity in Conditions of Oxidative Stress
Published in The American journal of pathology (2008)“…Cystic fibrosis is a lethal inherited disorder caused by mutations in a single gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR)…”
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13
Impact of nutrition on phenotype in CFTR-deficient mice
Published in Pediatric research (01-11-2007)“…To elucidate the impact of nutrition in cystic fibrosis (CF), we compared the phenotypic traits of Cftr -/- mice fed either a lipid-enriched liquid diet…”
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14
RNA biochemistry. Transcriptome-wide distribution and function of RNA hydroxymethylcytosine
Published in Science (American Association for the Advancement of Science) (15-01-2016)“…Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is…”
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15
Intracellular colocalization and interaction of IGF-binding protein-2 with the cyclin-dependent kinase inhibitor p21CIP1/WAF1 during growth inhibition
Published in Biochemical journal (15-12-2005)“…It is presently unknown whether any member of the IGFBP (insulin-like growth factor binding protein) family directly participates in the control of cell…”
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Oxidative stress response results in increased p21 degradation in cystic fibrosis lung epithelial cells
Published in Free radical biology & medicine (01-01-2006)“…Lung epithelium in cystic fibrosis (CF) patients is characterized by structural damage and altered repair due to oxidative stress. To gain insight into the…”
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Oxidative stress response results in increased p21 WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells
Published in Free radical biology & medicine (2006)“…Lung epithelium in cystic fibrosis (CF) patients is characterized by structural damage and altered repair due to oxidative stress. To gain insight into the…”
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Oxidative stress response results in increased p21WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells
Published in Free radical biology & medicine (01-01-2006)“…Lung epithelium in cystic fibrosis (CF) patients is characterized by structural damage and altered repair due to oxidative stress. To gain insight into the…”
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Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling
Published in The Journal of pharmacology and experimental therapeutics (01-09-2008)“…Sodium 4-phenylbutyrate (4-PBA) has attracted a great deal of attention in cystic fibrosis (CF) pathology due to its capacity to traffic DeltaF508-cystic…”
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Cystic fibrosis transmembrane conductance regulator controls lung proteasomal degradation and nuclear factor-kappaB activity in conditions of oxidative stress
Published in The American journal of pathology (01-05-2008)“…Cystic fibrosis is a lethal inherited disorder caused by mutations in a single gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR)…”
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