Search Results - "Bontempo, Paola"

Functional Properties of Natural Products and Human Health by Bontempo, Paola, De Masi, Luigi, Rigano, Daniela

“…Natural products (NPs), broadly defined as chemicals produced by living organisms including microbes, marine organisms, animals, fungi and plants, are widely…”
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SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism by Varghese, Benluvankar, Chianese, Ugo, Capasso, Lucia, Sian, Veronica, Bontempo, Paola, Conte, Mariarosaria, Benedetti, Rosaria, Altucci, Lucia, Carafa, Vincenzo, Nebbioso, Angela

“…Abstract Background Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved…”
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Therapeutic Potential of Natural Compounds Acting through Epigenetic Mechanisms in Cardiovascular Diseases: Current Findings and Future Directions by Bontempo, Paola, Capasso, Lucia, De Masi, Luigi, Nebbioso, Angela, Rigano, Daniela

“…Cardiovascular diseases (CVDs) remain a leading global cause of morbidity and mortality. These diseases have a multifaceted nature being influenced by a…”
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Comparative Phytochemical Characterization, Genetic Profile, and Antiproliferative Activity of Polyphenol-Rich Extracts from Pigmented Tubers of Different Solanum tuberosum Varieties by De Masi, Luigi, Bontempo, Paola, Rigano, Daniela, Stiuso, Paola, Carafa, Vincenzo, Nebbioso, Angela, Piacente, Sonia, Montoro, Paola, Aversano, Riccardo, D'Amelia, Vincenzo, Carputo, Domenico, Altucci, Lucia

“…Plants produce a vast array of biomolecules with beneficial effects for human health. In this study, polyphenol and anthocyanin-rich extracts (PAE) from…”
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Antiproliferative, antibacterial and antifungal activity of the lichen Xanthoria parietina and its secondary metabolite parietin by Basile, Adriana, Rigano, Daniela, Loppi, Stefano, Di Santi, Annalisa, Nebbioso, Angela, Sorbo, Sergio, Conte, Barbara, Paoli, Luca, De Ruberto, Francesca, Molinari, Anna Maria, Altucci, Lucia, Bontempo, Paola

“…Lichens are valuable natural resources used for centuries throughout the world as medicine, food, fodder, perfume, spices and dyes, as well as for other…”
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Molecular Docking Simulations on Histone Deacetylases (HDAC)-1 and -2 to Investigate the Flavone Binding by Scafuri, Bernardina, Bontempo, Paola, Altucci, Lucia, De Masi, Luigi, Facchiano, Angelo

“…Histone modifications through acetylation are fundamental for remodelling chromatin and consequently activating gene expression. The imbalance between…”
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ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis by Infante, Teresa, Franzese, Monica, Ruocco, Antonio, Schiano, Concetta, Affinito, Ornella, Pane, Katia, Memoli, Domenico, Rizzo, Francesca, Weisz, Alessandro, Bontempo, Paola, Grimaldi, Vincenzo, Berrino, Liberato, Soricelli, Andrea, Mauro, Ciro, Napoli, Claudio

“…Acute coronary syndrome (ACS) is the most severe clinical manifestation of coronary heart disease. We performed an epigenome-wide analysis of circulating CD4 +…”
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Health-Promoting Effects, Phytochemical Constituents and Molecular Genetic Profile of the Purple Carrot 'Purple Sun' ( Daucus carota L.) by Maresca, Viviana, Capasso, Lucia, Rigano, Daniela, Stornaiuolo, Mariano, Sirignano, Carmina, Piacente, Sonia, Cerulli, Antonietta, Marallo, Nadia, Basile, Adriana, Nebbioso, Angela, Giordano, Deborah, Facchiano, Angelo, De Masi, Luigi, Bontempo, Paola

“…The purple carrot cultivar 'Purple Sun' ( L.) is characterized by a relevant content of phenolic compounds and anthocyanins, which may play an important role…”
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RIP1-HAT1-SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer by Carafa, Vincenzo, Nebbioso, Angela, Cuomo, Francesca, Rotili, Dante, Cobellis, Gilda, Bontempo, Paola, Baldi, Alfonso, Spugnini, Enrico P, Citro, Gennaro, Chambery, Angela, Russo, Rosita, Ruvo, Menotti, Ciana, Paolo, Maravigna, Luca, Shaik, Jani, Radaelli, Enrico, De Antonellis, Pasquale, Tarantino, Domenico, Pirolli, Adele, Ragno, Rino, Zollo, Massimo, Stunnenberg, Hendrik G, Mai, Antonello, Altucci, Lucia

“…Alteration in cell death is a hallmark of cancer. A functional role regulating survival, apoptosis, and necroptosis has been attributed to RIP1/3 complexes. We…”
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Metabolite Profile and In Vitro Beneficial Effects of Black Garlic ( Allium sativum L.) Polar Extract by Bontempo, Paola, Stiuso, Paola, Lama, Stefania, Napolitano, Assunta, Piacente, Sonia, Altucci, Lucia, Molinari, Anna Maria, De Masi, Luigi, Rigano, Daniela

“…Over the centuries, humans have traditionally used garlic ( L.) as a food ingredient (spice) and remedy for many diseases. To confirm this, many extensive…”
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Chemical Composition of Thymus leucotrichus var. creticus Essential Oil and Its Protective Effects on Both Damage and Oxidative Stress in Leptodictyum riparium Hedw. Induced by Cadmium by Maresca, Viviana, Badalamenti, Natale, Ilardi, Vincenzo, Bruno, Maurizio, Bontempo, Paola, Basile, Adriana

“…The chemical profile of the essential oil (EO) of the aerial parts of var. (Lamiaceae), a taxon not previously studied, was investigated by GC-MS analysis,…”
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Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells by Gronemeyer, Hinrich, Altucci, Lucia, Nebbioso, Angela, Clarke, Nicole, Voltz, Emilie, Germain, Emmanuelle, Ambrosino, Concetta, Bontempo, Paola, Alvarez, Rosana, Schiavone, Ettore M, Ferrara, Felicetto, Bresciani, Francesco, Weisz, Alessandro, de Lera, Angel R

“…Chromatin is a dynamic macromolecular structure epigenetically modified to regulate specific gene expression. Altered chromatin function can lead to aberrant…”
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Sirtuin Inhibitor Cambinol Induces Cell Differentiation and Differently Interferes with SIRT1 and 2 at the Substrate Binding Site by Giordano, Deborah, Scafuri, Bernardina, De Masi, Luigi, Capasso, Lucia, Maresca, Viviana, Altucci, Lucia, Nebbioso, Angela, Facchiano, Angelo, Bontempo, Paola

“…Epigenetic mechanisms finely regulate gene expression and represent potential therapeutic targets. Cambinol is a synthetic heterocyclic compound that inhibits…”
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Phytochemical Characterization, Antioxidant, and Anti-Proliferative Activities of Wild and Cultivated Nigella damascena Species Collected in Sicily (Italy) by Scognamiglio, Monica, Maresca, Viviana, Basile, Adriana, Pacifico, Severina, Fiorentino, Antonio, Bruno, Maurizio, Badalamenti, Natale, Kapelusz, Marta, Marino, Pasquale, Capasso, Lucia, Bontempo, Paola, Bazan, Giuseppe

“…The use of seeds in the culinary field or as aerial parts infusions in the pharmaceutical and cosmetic fields is widely reported. The biological activity of…”
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Anticancer activities of anthocyanin extract from genotyped Solanum tuberosum L. “Vitelotte” by Bontempo, Paola, De Masi, Luigi, Carafa, Vincenzo, Rigano, Daniela, Scisciola, Lucia, Iside, Concetta, Grassi, Roberto, Molinari, Anna Maria, Aversano, Riccardo, Nebbioso, Angela, Carputo, Domenico, Altucci, Lucia

“…•Molecular genotyping of Vitelotte potato was identified promoting the use of this genetic resource by plant breeders.•Molecular analyses of anthocyanin action…”
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CYP17 and CYP19 gene polymorphisms in women affected with endometriosis by Vietri, Maria Teresa, M.D, Cioffi, Michele, M.D, Sessa, Marcella, Ph.D, Simeone, Serena, M.D, Bontempo, Paola, M.D, Trabucco, Elisabetta, M.D, Ardovino, Mario, M.D, Colacurci, Nicola, M.D, Molinari, Anna Maria, M.D, Cobellis, Luigi, M.D

“…Objective To investigate whether CYP17 T>C polymorphism and polymorphisms C1558T and Val80 of CYP19 are related to endometriosis. Design Clinical study…”
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The Beneficial Effects of Antioxidant Supplementation in Enteral Feeding in Critically Ill Patients: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial by Crimi, Ettore, Liguori, Antonio, Condorelli, Mario, Cioffi, Michele, Astuto, Marinella, Bontempo, Paola, Pignalosa, Orlando, Vietri, Maria Teresa, Molinari, Anna Maria, Sica, Vincenzo, Corte, Francesco Della, Napoli, Claudio

“…We investigated whether intervention with antioxidant vitamins C and E in enteral feeding influenced oxidative stress and clinical outcome in critically ill…”
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Arg72Pro p53 polymorphism in Italian women: no association with endometriosis by Vietri, Maria Teresa, M.D, Molinari, Anna Maria, M.D, Iannella, Iolanda, M.D, Cioffi, Michele, M.D, Bontempo, Paola, M.D, Ardovino, Mario, M.D, Scaffa, Cono, M.D, Colacurci, Nicola, M.D, Cobellis, Luigi, M.D., Ph.D

“…p53 codon 72 polymorphism in Italian women have a minor role in determining genetic susceptibility to endometriosis. The racial differences, in association…”
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Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells by Bontempo, Paola, Mita, Luigi, Doto, Antonella, Miceli, Marco, Nebbioso, Angela, Lepore, Ilaria, Franci, GianLuigi, Menafra, Roberta, Carafa, Vincenzo, Conte, Mariarosaria, De Bellis, Floriana, Manzo, Fabio, Di Cerbo, Vincenzo, Benedetti, Rosaria, D'Amato, Loredana, Marino, Maria, Bolli, Alessandro, Del Pozzo, Giovanna, Diano, Nadia, Portaccio, Marianna, Mita, Gustavo D, Vietri, Maria Teresa, Cioffi, Michele, Nola, Ernesto, Dell'aversana, Carmela, Sica, Vincenzo, Molinari, Anna Maria, Altucci, Lucia

“…BPA (bisphenol A or 2,2-bis(4-hydroxy-phenol)propane) is present in the manufacture of polycarbonate plastic and epoxy resins, which can be used in…”
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Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential by Sharifi-Rad, Javad, Quispe, Cristina, Castillo, Carla Marina Salgado, Caroca, Rodrigo, Lazo-Vélez, Marco A., Antonyak, Halyna, Polishchuk, Alexandr, Lysiuk, Roman, Oliinyk, Petro, De Masi, Luigi, Bontempo, Paola, Martorell, Miquel, Daştan, Sevgi Durna, Rigano, Daniela, Wink, Michael, Cho, William C.

“…Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary metabolite in many plant taxa. EA content is considerable in…”
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