Search Results - "Bonnot, Guillaume"
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Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria
Published in International journal of infectious diseases (01-12-2019)“…•Artemisinin-based treatment of malaria and risks of resistance.•Inter-individual variability of ART and DHA pharmacokinetic parameters.•Positive correlation…”
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Pre-referral intranasal artesunate powder for cerebral malaria: a proof-of-concept study
Published in Malaria journal (11-10-2022)“…Abstract Background Malaria still kills young children in rural endemic areas because early treatment is not available. Thus, the World Health Organization…”
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Diagnostic accuracy of fluorescence flow-cytometry technology using Sysmex XN-31 for imported malaria in a non-endemic setting
Published in Parasite (Paris) (2022)“…Malaria diagnosis based on microscopy is impaired by the gradual disappearance of experienced microscopists in non-endemic areas. Aside from the conventional…”
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Interaction between environment, nutrient-derived metabolites and immunity: A possible role in malaria susceptibility/resistance in Fulani and Dogon of Mali
Published in PloS one (20-12-2017)“…The role of some nutrient-derived metabolites on the innate and adaptive immune responses is now established. Global research approach investigating the…”
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Assessment of quantitative and semi-quantitative biological test methods of artesunate in vitro
Published in Parasite (Paris) (2022)“…Artesunate is the current most potent antimalarial drug widely used for the treatment of malaria. Considering the emergence of artemisinin resistance, several…”
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Recrudescence of a high parasitaemia, severe Plasmodium falciparum malaria episode, treated by artesunate monotherapy
Published in International journal of infectious diseases (01-04-2021)“…[Display omitted] •A patient with severe malaria suffered a severe recrudescent episode.•Artesunate monotherapy is associated with a higher risk of…”
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Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening patients with imported malaria in a non-endemic setting
Published in Parasite (Paris) (2017)“…Sensitive and easy-to-perform methods for the diagnosis of malaria are not yet available. Improving the limit of detection and following the requirements for…”
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An outbreak of locally acquired Plasmodium vivax malaria among migrant workers in Oman
Published in Parasite (Paris) (2017)“…Plasmodium vivax is the most widely distributed human malaria parasite. Outside sub-Saharan Africa, the proportion of P. vivax malaria is rising. A major cause…”
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Therapeutic efficacy of artemether-lumefantrine for Plasmodium vivax infections in a prospective study in Guyana
Published in Malaria journal (19-10-2012)“…In Guyana, chloroquine + primaquine is used for the treatment of vivax malaria. A worldwide increase of chloroquine resistance in Plasmodium vivax led to…”
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Nanoparticle tracking analysis of natural hemozoin from Plasmodium parasites
Published in Acta tropica (01-02-2024)“…Hemozoin is a byproduct of hemoglobin digestion crucial for parasite survival. It forms crystals that can be of interest as drug targets or biomarkers of…”
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Paper functionalization for detection of Plasmodium falciparum DNA using square waves voltammetry
Published in Talanta (Oxford) (15-01-2023)“…Malaria elimination is a major goal to be reached in the next decade. Significant progress were made in the past, and the prevalence decreased in many areas…”
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Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials
Published in European journal of medicinal chemistry (05-12-2022)“…A series of ferrocenyl-containing γ-hydroxy-γ-lactam tetramates were prepared in 2–3 steps through ring opening-ring closure (RORC) process of…”
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The first case of artemisinin treatment failure of Plasmodium falciparum imported to Oman from Tanzania
Published in Journal of travel medicine (18-05-2023)“…We present the clinical and genomic epidemiological perspective of the first case of Artesunate treatment failure in an Omani citizen admitted to a hospital in…”
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Efficacy of intranasal administration of artesunate in experimental cerebral malaria
Published in Malaria journal (16-12-2014)“…Improving management of patients suffering from cerebral malaria is needed to reduce the devastating mortality and morbidity of the disease in endemic areas…”
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7-Chloro-4-aminoquinoline γ-hydroxy-γ-lactam derived-tetramates as a new family of antimalarial compounds
Published in Bioorganic & medicinal chemistry letters (01-11-2016)“…[Display omitted] In this Letter we report on an efficient and short 2–3 steps synthesis of γ-hydroxy-γ-lactam derived-tetramates bearing a…”
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Drying anti-malarial drugs in vitro tests to outsource SYBR green assays
Published in Malaria journal (21-02-2015)“…Measurement of anti-malarial drug efficacy and resistance relies mainly on in vivo clinical trials, in vitro/ex vivo assays and molecular markers detection…”
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Evaluation of the malaria rapid diagnostic test VIKIA malaria Ag Pf/Pan™ in endemic and non-endemic settings
Published in Malaria journal (06-06-2013)“…Malaria rapid diagnostic tests (RDTs) are a useful tool in endemic malaria countries, where light microscopy is not feasible. In non-endemic countries they can…”
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Genetic diversity of Plasmodium vivax metacaspase 1 and Plasmodium vivax multi-drug resistance 1 genes of field isolates from Mauritania, Sudan and Oman
Published in Malaria journal (02-02-2017)“…Plasmodium vivax is the second most important human malaria parasite, widely spread across the world. This parasite is associated with important issues in the…”
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