Search Results - "Bonnin, Marc"

Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism by Niu, Congrong, Li, Li, Daffis, Stephane, Lucifora, Julie, Bonnin, Marc, Maadadi, Sarah, Salas, Eduardo, Chu, Ruth, Ramos, Hilario, Livingston, Christine M., Beran, Rudolf K., Garg, Abhishek V., Balsitis, Scott, Durantel, David, Zoulim, Fabien, Delaney, William E., Fletcher, Simon P.

“…[Display omitted] •GS-9620 has no direct antiviral activity against HBV.•Type I IFN induced by GS-9620 durably suppresses HBV without reducing cccDNA…”
Get full text

Higher mortality and intubation rate in COVID-19 patients treated with noninvasive ventilation compared with high-flow oxygen or CPAP by Marti, Sergi, Carsin, Anne-Elie, Sampol, Júlia, Pallero, Mercedes, Aldas, Irene, Marin, Toni, Lujan, Manel, Lalmolda, Cristina, Sabater, Gladis, Bonnin-Vilaplana, Marc, Peñacoba, Patricia, Martinez-Llorens, Juana, Tárrega, Julia, Bernadich, Óscar, Córdoba-Izquierdo, Ana, Lozano, Lourdes, Mendez, Susana, Vélez-Segovia, Eduardo, Prina, Elena, Eizaguirre, Saioa, Balañá-Corberó, Ana, Ferrer, Jaume, Garcia-Aymerich, Judith

“…The effectiveness of noninvasive respiratory support in severe COVID-19 patients is still controversial. We aimed to compare the outcome of patients with…”
Get full text

Long-term respiratory consequences of COVID-19 related pneumonia: a cohort study by Eizaguirre, Saioa, Sabater, Gladis, Belda, Sònia, Calderón, Juan Carlos, Pineda, Victor, Comas-Cufí, Marc, Bonnin, Marc, Orriols, Ramon

“…Abstract Background Our aims were to describe respiratory sequelae up to 12 months after discharge in COVID-19 patients with severe pneumonia requiring…”
Get full text

A Chemically Defined TLR3 Agonist with Anticancer Activity by Le Naour, Julie, Thierry, Sylvain, Scuderi, Sarah Adriana, Boucard-Jourdin, Mathilde, Liu, Peng, Bonnin, Marc, Pan, Yuhong, Perret, Clémence, Zhao, Liwei, Mao, Misha, Renoux, Chloé, Pérez-Lanzón, María, Martin, Baptiste, Kepp, Oliver, Kroemer, Guido, Werlé, Bettina

“…Toll-like receptor 3 (TLR3) agonists such as polyinosinic:polycytidylic acid (poly(I:C)) have immunostimulatory effects that can be taken advantage of to…”
Get full text

Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment by Peracaula, Miriam, Sebastian, Laura, Francisco, Iria, Vilaplana, Marc Bonnin, Rodríguez-Chiaradía, Diego A, Tura-Ceide, Olga

“…Pulmonary Embolism (PE) is a life-threatening condition initiated by the presence of blood clots in the pulmonary arteries, leading to severe morbidity and…”
Get full text

Cleaved/associated TLR3 represents the primary form of the signaling receptor by Toscano, Florent, Estornes, Yann, Virard, François, Garcia-Cattaneo, Alejandra, Pierrot, Audrey, Vanbervliet, Béatrice, Bonnin, Marc, Ciancanelli, Michael J, Zhang, Shen-Ying, Funami, Kenji, Seya, Tsukasa, Matsumoto, Misako, Pin, Jean-Jacques, Casanova, Jean-Laurent, Renno, Toufic, Lebecque, Serge

“…TLR3 belongs to the family of intracellular TLRs that recognize nucleic acids. Endolysosomal localization and cleavage of intracellular TLRs play pivotal roles…”
Get full text

TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization by Thierry, Sylvain, Maadadi, Sarah, Berton, Aurore, Dimier, Laura, Perret, Clémence, Vey, Nelly, Ourfali, Saïd, Saccas, Mathilde, Caron, Solène, Boucard-Jourdin, Mathilde, Colombel, Marc, Werle, Bettina, Bonnin, Marc

“…Toll-like receptor 3 (TLR3) is an innate immune receptor that recognizes double-stranded RNA (dsRNA) and induces inflammation in immune and normal cells to…”
Get full text

Endothelial dysfunction and cardiovascular risk in post-COVID-19 patients after 6- and 12-months SARS-CoV-2 infection by Poyatos, Paula, Luque, Neus, Sabater, Gladis, Eizaguirre, Saioa, Bonnin, Marc, Orriols, Ramon, Tura-Ceide, Olga

“…Introduction SARS-CoV-2 infection causes severe endothelial damage, an essential step for cardiovascular complications. Endothelial-colony forming cells…”
Get full text

Souvenirs d’Australie et écriture du moi dans June in Her Spring, de Colin MacInnes by Jean-Marc Bonnin

Get full text

Expression and functionality of Toll- and RIG-like receptors in HepaRG cells by Luangsay, Souphalone, Ait-Goughoulte, Malika, Michelet, Maud, Floriot, Océane, Bonnin, Marc, Gruffaz, Marion, Rivoire, Michel, Fletcher, Simon, Javanbakht, Hassan, Lucifora, Julie, Zoulim, Fabien, Durantel, David

“…Graphical abstract…”
Get full text

Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes by Lucifora, Julie, Bonnin, Marc, Aillot, Ludovic, Fusil, Floriane, Maadadi, Sarah, Dimier, Laura, Michelet, Maud, Floriot, Océane, Ollivier, Anaïs, Rivoire, Michel, Ait-Goughoulte, Malika, Daffis, Stéphane, Fletcher, Simon P., Salvetti, Anna, Cosset, François-Loïc, Zoulim, Fabien, Durantel, David

“…Current therapies for chronic hepatitis B virus (HBV) infections are effective at decreasing the viral load in serum, but do not lead to viral eradication…”
Get full text

Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis by Bonnin, Marc, Fares, Nadim, Testoni, Barbara, Estornes, Yann, Weber, Kathrin, Vanbervliet, Béatrice, Lefrançois, Lydie, Garcia, Amandine, Kfoury, Alain, Pez, Floriane, Coste, Isabelle, Saintigny, Pierre, Viari, Alain, Lang, Kévin, Guey, Baptiste, Hervieu, Valérie, Bancel, Brigitte, Bartoch, Birke, Durantel, David, Renno, Toufic, Merle, Philippe, Lebecque, Serge

“…[Display omitted] •Downregulation of TLR3 in HCC is associated with poor prognosis and with resistance to TLR3-triggered apoptosis.•Downregulation of TLR3 is…”
Get full text

Interaction between Toll-Like Receptor 9-CpG Oligodeoxynucleotides and Hepatitis B Virus Virions Leads to Entry Inhibition in Hepatocytes and Reduction of Alpha Interferon Production by Plasmacytoid Dendritic Cells by Aillot, Ludovic, Bonnin, Marc, Ait-Goughoulte, Malika, Bendriss-Vermare, Nathalie, Maadadi, Sarah, Dimier, Laura, Subic, Miroslava, Scholtes, Caroline, Najera, Isabel, Zoulim, Fabien, Lucifora, Julie, Durantel, David

“…We previously reported that Toll-like receptor 9 (TLR9)-CpG oligonucleotides could inhibit the establishment of hepatitis B virus (HBV) infections in…”
Get full text

Efficacy of continuous positive airway pressure treatment on 5‐year survival in patients with ischaemic stroke and obstructive sleep apnea: a randomized controlled trial by Parra, Olga, Sánchez‐Armengol, Ángeles, Capote, Francisco, Bonnin, Marc, Arboix, Adrià, Campos‐Rodríguez, Francisco, Pérez‐Ronchel, José, Durán‐Cantolla, Joaquín, Martínez‐Null, Cristina, Peña, Mónica, Jiménez, Maria Carmen, Masa, Fernando, Casadon, Ignacio, Alonso, Maria Luz, Macarrón, José L.

“…Summary The main purpose of the present analysis is to assess the influence of introducing early nasal continuous positive airway pressure (nCPAP) treatment on…”
Get full text

A Chemically Defined TLR3 Agonist with Anticancer Activity by Le Naour, Julie, Thierry, Sylvain, Scuderi, Sarah Adriana, Boucard-Jourdin, Mathilde, Liu, Peng, Bonnin, Marc, Pan, Yuhong, Perret, Clémence, Zhao, Liwei, Mao, Misha, Renoux, Chloé, Pérez-Lanzón, María, Martin, Baptiste, Kepp, Oliver, Kroemer, Guido, Werlé, Bettina

Get full text

Release of c-FLIP brake selectively sensitizes human cancer cells to TLR3-mediated apoptosis by Alkurdi, Lugain, Virard, François, Vanbervliet, Béatrice, Weber, Kathrin, Toscano, Florent, Bonnin, Marc, Le Stang, Nolwenn, Lantuejoul, Sylvie, Micheau, Olivier, Renno, Toufic, Lebecque, Serge, Estornes, Yann

“…Toll-like receptor 3 (TLR3) mediates innate immune responses by sensing viral dsRNA, but also induces apoptosis selectively in cancer cells. Our analysis by…”
Get full text

Characterization of Pattern Recognition Receptor Expression and Functionality in Liver Primary Cells and Derived Cell Lines by Faure-Dupuy, Suzanne, Vegna, Serena, Aillot, Ludovic, Dimier, Laura, Esser, Knud, Broxtermann, Mathias, Bonnin, Marc, Bendriss-Vermare, Nathalie, Rivoire, Michel, Passot, Guillaume, Lesurtel, Mickaël, Mabrut, Jean-Yves, Ducerf, Christian, Salvetti, Anna, Protzer, Ulrike, Zoulim, Fabien, Durantel, David, Lucifora, Julie

“…Different liver cell types are endowed with immunological properties, including cell-intrinsic innate immune functions that are important to initially control…”
Get full text

Abstract 2085: The specific TLR3-agonist TL-532 induces life-long anti-tumor autovaccination, cross-immunity against unrelated cancers and reverses resistance to immune checkpoint inhibitors by Bonnin, Marc, Ourfali, Saïd, Boucard-Jourdin, Mathilde, Perret, Clémence, Renoux, Chloé, Vey, Nelly, Colombel, Marc, Werlé, Bettina, Thierry, Sylvain

“…Abstract Background: Toll-Like Receptor 3 (TLR3) is an innate immunity receptor that triggers inflammation by recognizing double stranded RNAs. In the past…”
Get full text

Corrigendum to “Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis” [J Hepatol 71 (2019) 763–772] by Bonnin, Marc, Fares, Nadim, Testoni, Barbara, Estornes, Yann, Weber, Kathrin, Vanbervliet, Béatrice, Lefrançois, Lydie, Garcia, Amandine, Kfoury, Alain, Pez, Floriane, Coste, Isabelle, Saintigny, Pierre, Viari, Alain, Lang, Kévin, Guey, Baptiste, Petrilli, Virginie, Hervieu, Valérie, Bancel, Brigitte, Bartosch, Birke, Durantel, David, Renno, Toufic, Merle, Philippe, Lebecque, Serge

Get full text

Factors associated with hospital admission for exacerbation of chronic obstructive pulmonary disease by Alcázar, Bernardino, García-Polo, Cayo, Herrejón, Alberto, Ruiz, Luis Alberto, de Miguel, Javier, Ros, José Antonio, García-Sidro, Patricia, Conde, Gema Tirado, López-Campos, José Luis, Martínez, Carlos, Costán, Joaquin, Bonnin, Marc, Mayoralas, Sagrario, Miravitlles, Marc

“…INTRODUCTIONExacerbations of Chronic Obstructive Pulmonary Disease (COPD) that require hospital admission have a major impact on the progression of disease and…”
Get full text