CD4+ T cell counts in initiation of antiretroviral therapy in HIV infected asymptomatic individuals; controversies and inconsistencies

CD4+ T cell counts in initiation of antiretroviral therapy in HIV infected asymptomatic individuals; controversies and inconsistencies

Highlights • Assesses available data on optimal time to initiate therapy in HIV-infected asymptomatic individuals with respect to CD4+ T cell threshold. • Discuss arguments for and against early or late initiation of ART. • Discusses available information from 1998 through 2015. • Presents authors c...

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Bibliographic Details
Published in:Immunology letters Vol. 168; no. 2; pp. 279 - 284
Main Authors: Maina, E.K, Bonney, E.Y, Bukusi, E.A, Sedegah, M, Lartey, M, Ampofo, W.K
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 01-12-2015
Subjects:
AIDS
Allergy and Immunology
Anti-HIV Agents - therapeutic use
Antiretroviral therapy
CD4 Lymphocyte Count
CD4+ T cell
Europe
HIV
HIV - drug effects
HIV - immunology
HIV - physiology
HIV Infections - drug therapy
HIV Infections - immunology
HIV Infections - virology
Humans
Practice Guidelines as Topic
Time Factors
United States
World Health Organization
United States
Europe
AIDS
CD4+ T cell
HIV
Antiretroviral therapy
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Description
Summary:Highlights • Assesses available data on optimal time to initiate therapy in HIV-infected asymptomatic individuals with respect to CD4+ T cell threshold. • Discuss arguments for and against early or late initiation of ART. • Discusses available information from 1998 through 2015. • Presents authors conclusion and views.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2015.10.005