Search Results - "Bonnet, Sandrine"

RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53 by Jacquier, Valentin, Gitenay, Delphine, Fritsch, Samuel, Bonnet, Sandrine, Győrffy, Balázs, Jalaguier, Stéphan, Linares, Laetitia K., Cavaillès, Vincent, Teyssier, Catherine

“…Glycolysis is essential to support cancer cell proliferation, even in the presence of oxygen. The transcriptional co-regulator RIP140 represses the activity of…”
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RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells by Sfeir, Nour, Kajdan, Marilyn, Jalaguier, Stéphan, Bonnet, Sandrine, Teyssier, Catherine, Pyrdziak, Samuel, Yuan, Rong, Bousquet, Emilie, Maraver, Antonio, Bernex, Florence, Pirot, Nelly, Boissière‐Michot, Florence, Castet‐Nicolas, Audrey, Lapierre, Marion, Cavaillès, Vincent

“…The transcription factor receptor‐interacting protein 140 (RIP140) regulates intestinal homeostasis and tumorigenesis through Wnt signaling. In this study, we…”
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Specific Activity of Class II Histone Deacetylases in Human Breast Cancer Cells by Duong, Vanessa, Bret, Caroline, Altucci, Lucia, Mai, Antonello, Duraffourd, Céline, Loubersac, Julie, Harmand, Pierre-Olivier, Bonnet, Sandrine, Valente, Sergio, Maudelonde, Thierry, Cavailles, Vincent, Boulle, Nathalie

“…Although numerous studies have underlined the role of histone deacetylases (HDAC) in breast physiology and tumorigenesis, little is known on the particular…”
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Receptor-Interacting Protein 140 Differentially Regulates Estrogen Receptor-Related Receptor Transactivation Depending on Target Genes by Castet, Audrey, Herledan, Adrien, Bonnet, Sandrine, Jalaguier, Stéphan, Vanacker, Jean-Marc, Cavaillès, Vincent

“…We have investigated the effects of receptor-interacting protein 140 (RIP140) on transcriptional regulation by estrogen receptor-related receptors (ERRs). We…”
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Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial by Hardt, Karin, Vandebosch, An, Sadoff, Jerald, Le Gars, Mathieu, Schuitemaker, Hanneke, Albertson, Timothy E., Velarde, Luis Humberto Anaya, Bhushanan, Jisha, Chen, Bohang, Chetty, Polan, Custers, Jerome, Delanghe, Hilde, Duca, Anna, Pinheiro, Jose, Roels, Sanne, Salas, Jose, Vaissiere, Nathalie, Xu, Jiajun, Goecker, Erin A., Takuva, Simbarashe G., Ahsan, Habibul, Bajwa, Ali, Berdaï, Driss, Biagioni Santos, Maria Silvia, Binnian, Ian, Bisnauthsing, Karen, Boivin, Jean-Marc, Botelho-Nevers, Elisabeth, Buntinx, Erik, Carr, Quito Osuna, Cereto Castro, Fernando, Chavoustie, Steven, D'Onofrio, Valentino, Dargan, Paul, Del Pozo, Jose Luis, Desai, Amisha, DiBuono, Mark, Duncan, Christopher, Elzi, Stanton, Emmett, Stevan, Evans, Mim, Farah, Theo, Floutier, Catherine, Flume, Patrick, Ford, Stacy, Garcia Diaz, Julia, Gardener, Zoe, Gauteul, Pascale, Gillet, Claudia, Go, Herschel Don D., Gokani, Karishma, Gonthier, Damien, Greenberg, Richard, Grobbelaar, Coert, Guancia, Adonis, Hakkarainen, Gloria, Hellstrom-Louw, Elizabeth, Hussen, Nazreen, Jackson, Yvonne, Jain, Manish, João Filho, Esaú Custódio, Jumeras, Analyn, Kimmel, Murray, Lazarus, Rajeka, Lins, Muriel, Maia, Bernardo Porto, Marín-Candon, Alícia, McCaughan, Frank, McCormack, Louise, McGettigan, John, Mehra, Purvi, Molto Marhuenda, Jose, Mullan, Daniel, Munro, Alasdair, Newman Lobato Souza, Tamara, Oliver, Abigail, Otero Romero, Susana, Pacurar, Mihaela, Pinto, S. Jerry, Presti, Rachel, Ramesh, Mayur, Riegel Santos, Breno, Riesenberg, Robert, Riffer, Ernie, Roche, Siobhan, Rose, Katie, Rosellini, Pietro, Rossignol, Patrick, Safirstein, Beth, Santhosh, Smrithi, Seco-Meseguer, Enrique, Seep, Michael, Short, Philip, Tellalian, David, Thiriphoo, Nang, Thomas, Judith, Thomas, Nicholas, Webster, Brian, Winston, Alan, Zervos, Marcus

“…Despite the availability of effective vaccines against COVID-19, booster vaccinations are needed to maintain vaccine-induced protection against variant strains…”
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RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis by Lapierre, Marion, Bonnet, Sandrine, Bascoul-Mollevi, Caroline, Ait-Arsa, Imade, Jalaguier, Stéphan, Del Rio, Maguy, Plateroti, Michela, Roepman, Paul, Ychou, Marc, Pannequin, Julie, Hollande, Frédéric, Parker, Malcolm, Cavailles, Vincent

“…Deregulation of the Wnt/APC/β-catenin signaling pathway is an important consequence of tumor suppressor APC dysfunction. Genetic and molecular data have…”
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Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors by Lapierre, Marion, Linares, Aurélien, Dalvai, Mathieu, Duraffourd, Céline, Bonnet, Sandrine, Boulahtouf, Abdelhay, Rodriguez, Carmen, Jalaguier, Stéphan, Assou, Said, Orsetti, Beatrice, Balaguer, Patrick, Maudelonde, Thierry, Blache, Philippe, Bystricky, Kerstin, Boulle, Nathalie, Cavaillès, Vincent

“…Histone lysine acetylation is an epigenetic mark regulated by histone acetyltransferases and histone deacetylases (HDAC) which plays an important role in…”
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Negative Regulation of Estrogen Signaling by ERβ and RIP140 in Ovarian Cancer Cells by Docquier, Aurélie, Garcia, Aurélie, Savatier, Julien, Boulahtouf, Abdel, Bonnet, Sandrine, Bellet, Virginie, Busson, Muriel, Margeat, Emmanuel, Jalaguier, Stéphan, Royer, Cathy, Balaguer, Patrick, Cavaillès, Vincent

“…In hormone-dependent tissues such as breast and ovary, tumorigenesis is associated with an altered expression ratio between the two estrogen receptor (ER)…”
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RIP140 Represses Intestinal Paneth Cell Differentiation and Interplays with SOX9 Signaling in Colorectal Cancer by Gleizes, Antoine, Triki, Mouna, Bonnet, Sandrine, Baccari, Naomi, Jimenez-Dominguez, Gabriel, Covinhes, Aurélie, Pirot, Nelly, Blache, Philippe, Yuan, Rong, Győrffy, Balázs, Cavaillès, Vincent, Lapierre, Marion

“…RIP140 is a major transcriptional coregulator of gut homeostasis and tumorigenesis through the regulation of Wnt/APC signaling. Here, we investigated the…”
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Differential regulation of estrogen receptor α turnover and transactivation by Mdm2 and stress-inducing agents by DUONG, Vanessa, BOULLE, Nathalie, DAUJAT, Sylvain, CHAUVET, Jérome, BONNET, Sandrine, NEEL, Henry, CAVAILLES, Vincent

“…In mammalian cells, the level of estrogen receptor alpha (ERalpha) is rapidly decreased upon estrogen treatment, and this regulation involves proteasome…”
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A Truncated NRIP1 Mutant Amplifies Microsatellite Instability of Colorectal Cancer by Regulating MSH2/MSH6 Expression, and Is a Prognostic Marker of Stage III Tumors by Palassin, Pascale, Lapierre, Marion, Pyrdziak, Samuel, Wagner, Antoine, Stehle, Régine, Corsini, Carole, Duffour, Jacqueline, Bonnet, Sandrine, Boulahtouf, Abdelhay, Rodriguez, Carmen, Ho-Pun-Cheung, Alexandre, Lopez-Crapez, Evelyne, Boissière-Michot, Florence, Bibeau, Frédéric, Thezenas, Simon, Elarouci, Nabila, Selves, Janick, Hoffmann, Jean-Sébastien, Roepman, Paul, Mazard, Thibault, Buhard, Olivier, Duval, Alex, Jalaguier, Stéphan, Cavaillès, Vincent, Castet-Nicolas, Audrey

“…Microsatellite instability (MSI) is related to the alteration of mismatch repair (MMR) genes and plays a key role in colorectal cancer (CRC) pathogenesis. We…”
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RIP140 regulates POLK gene expression and the response to alkylating drugs in colon cancer cells by Palassin, Pascale, Lapierre, Marion, Bonnet, Sandrine, Pillaire, Marie-Jeanne, Győrffy, Balázs, Teyssier, Catherine, Jalaguier, Stéphan, Hoffmann, Jean-Sébastien, Cavaillès, Vincent, Castet-Nicolas, Audrey

“…Aim: The transcription factor RIP140 (receptor interacting protein of 140 kDa) is involved in intestinal tumorigenesis. It plays a role in the control of…”
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RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis: RIP140 in colon cancer by Lapierre, Marion, Bonnet, Sandrine, Bascoul-Mollevi, Caroline, Ait-Arsa, Imade, Jalaguier, Stéphan, del Rio, Maguy, Plateroti, Michela, Roepman, Paul, Ychou, Marc, Pannequin, Julie, Hollande, Frédéric, Parker, Malcolm, Cavailles, Vincent

“…Deregulation of the Wnt/APC/β-catenin signaling pathway is an important consequence of tumor suppressor APC dysfunction. Genetic and molecular data have…”
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Multiple domains of the Receptor‐Interacting Protein 140 contribute to transcription inhibition by Castet, Audrey, Boulahtouf, Abdelhay, Versini, Gwennaëlle, Bonnet, Sandrine, Augereau, Patrick, Vignon, Françoise, Khochbin, Saadi, Jalaguier, Stéphan, Cavaillès, Vincent

“…In this study, we have investigated the role of C‐terminal binding proteins (CtBPs) and histone deacetylases (HDACs) in the repressive activity of the nuclear…”
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Estrogen receptor cofactors expression in breast and endometrial human cancer cells by Thenot, Sandrine, Charpin, Magali, Bonnet, Sandrine, Cavailles, Vincent

“…In order to approach the molecular basis of the tissue-specific agonistic activity of antioestrogens, we have compared, at the mRNA level, the expression of…”
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HIV education in the formal curriculum by Nsubuga, Yusuf K., Bonnet, Sandrine

“…The AIDS epidemic presents a complex of issues that require global answers, involving entire societies. The only sustainable solution is to include all sectors…”
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N‑[6-(4-Butanoyl-5-methyl‑1H‑pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]‑1H‑indole-3-carboxamide (SAR216471), a Novel Intravenous and Oral, Reversible, and Directly Acting P2Y12 Antagonist by Boldron, Christophe, Besse, Angélina, Bordes, Marie-Françoise, Tissandié, Stéphanie, Yvon, Xavier, Gau, Benjamin, Badorc, Alain, Rousseaux, Tristan, Barré, Guillaume, Meneyrol, Jérôme, Zech, Gernot, Nazare, Marc, Fossey, Valérie, Pflieger, Anne-Marie, Bonnet-Lignon, Sandrine, Millet, Laurence, Briot, Christophe, Dol, Frédérique, Hérault, Jean-Pascal, Savi, Pierre, Lassalle, Gilbert, Delesque, Nathalie, Herbert, Jean-Marc, Bono, Françoise

“…In the search of a potential backup for clopidogrel, we have initiated a HTS campaign designed to identify novel reversible P2Y12 antagonists. Starting from a…”
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N -[6-(4-Butanoyl-5-methyl-1 H -pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1 H -indole-3-carboxamide (SAR216471), a Novel Intravenous and Oral, Reversible, and Directly Acting P2Y12 Antagonist by Boldron, Christophe, Besse, Angélina, Bordes, Marie-Françoise, Tissandié, Stéphanie, Yvon, Xavier, Gau, Benjamin, Badorc, Alain, Rousseaux, Tristan, Barré, Guillaume, Meneyrol, Jérôme, Zech, Gernot, Nazare, Marc, Fossey, Valérie, Pflieger, Anne-Marie, Bonnet-Lignon, Sandrine, Millet, Laurence, Briot, Christophe, Dol, Frédérique, Hérault, Jean-Pascal, Savi, Pierre, Lassalle, Gilbert, Delesque, Nathalie, Herbert, Jean-Marc, Bono, Françoise

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Effect of Ligand and DNA Binding on the Interaction between Human Transcription Intermediary Factor 1α and Estrogen Receptors by Thénot, Sandrine, Bonnet, Sandrine, Boulahtouf, Abdelhay, Margeat, Emmanuel, Royer, Catherine A, Borgna, Jean-Louis, Cavaillès, Vincent

“…Hormonal regulation of gene activity is mediated by nuclear receptors acting as ligand-activated transcription factors. To achieve efficient regulation of gene…”
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Both estradiol and tamoxifen decrease proliferation and invasiveness of cancer cells transfected with a mutated estrogen receptor by Garcia, Marcel, Derocq, Danielle, Platet, Nadine, Bonnet, Sandrine, Brouillet, Jean-Paul, Touitou, Isabelle, Rochefort, Henri

“…Previous studies have shown that, after wild-type estrogen receptor (ER) transfection in ER-negative breast cancer cells, estradiol but not tamoxifen prevents…”
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