Search Results - "Bonnereau, Julie"
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Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment
Published in Journal for immunotherapy of cancer (14-03-2019)“…Immunotherapies still fail to benefit colorectal cancer (CRC) patients. Relevant functional assays aimed at studying these failures and the efficacy of cancer…”
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KLRG1 and CD103 Expressions Define Distinct Intestinal Tissue-Resident Memory CD8 T Cell Subsets Modulated in Crohn's Disease
Published in Frontiers in immunology (12-05-2020)“…Intestinal tissue-resident memory CD8 T cells (Trm) are non-recirculating effector cells ideally positioned to detect and react to microbial infections in the…”
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Autologous organoid co-culture model reveals T cell-driven epithelial cell death in Crohn’s Disease
Published in Frontiers in immunology (10-11-2022)“…Lympho-epithelial interactions between intestinal T resident memory cells (Trm) and the epithelium have been associated with inflammatory bowel disease (IBD)…”
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Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition
Published in Gut (01-04-2023)“…T cells are major effectors of the antitumoural immune response. Their activation by tumour-associated antigens can unleash their proliferation and cytotoxic…”
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Assessment of the reliability of MSI status and dMMR proteins deficiency screening on endoscopic biopsy material in esophagus and gastric adenocarcinoma
Published in Digestive and liver disease (01-08-2023)“…Microsatellite instability (MSI) is a negative predictive factor for neoadjuvant chemotherapy in resectable oesogastric adenocarcinoma and a crucial…”
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Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis
Published in Science advances (18-10-2024)“…A major therapeutic barrier in melanoma is the coexistence of diverse cellular states marked by distinct metabolic traits. Transitioning from a proliferative…”
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