Search Results - "Bonner, Maeve"

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity by Victor, Matheus B., Leary, Noelle, Luna, Xochitl, Meharena, Hiruy S., Scannail, Aine Ni, Bozzelli, P. Lorenzo, Samaan, George, Murdock, Mitchell H., von Maydell, Djuna, Effenberger, Audrey H., Cerit, Oyku, Wen, Hsin-Lan, Liu, Liwang, Welch, Gwyneth, Bonner, Maeve, Tsai, Li-Huei

“…Apolipoprotein E4 (APOE4) is the greatest known genetic risk factor for developing sporadic Alzheimer’s disease. How the interaction of APOE4 microglia with…”
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A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance by Newby, Gregory A., Kiriakov, Szilvia, Hallacli, Erinc, Kayatekin, Can, Tsvetkov, Peter, Mancuso, Christopher P., Bonner, J. Maeve, Hesse, William R., Chakrabortee, Sohini, Manogaran, Anita L., Liebman, Susan W., Lindquist, Susan, Khalil, Ahmad S.

“…Protein aggregation is a hallmark of many diseases but also underlies a wide range of positive cellular functions. This phenomenon has been difficult to study…”
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Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes by Blanchard, Joel W., Bula, Michael, Davila-Velderrain, Jose, Akay, Leyla Anne, Zhu, Lena, Frank, Alexander, Victor, Matheus B., Bonner, Julia Maeve, Mathys, Hansruedi, Lin, Yuan-Ta, Ko, Tak, Bennett, David A., Cam, Hugh P., Kellis, Manolis, Tsai, Li-Huei

“…In Alzheimer’s disease, amyloid deposits along the brain vasculature lead to a condition known as cerebral amyloid angiopathy (CAA), which impairs blood–brain…”
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Author Correction: Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes by Blanchard, Joel W., Bula, Michael, Davila-Velderrain, Jose, Akay, Leyla Anne, Zhu, Lena, Frank, Alexander, Victor, Matheus B., Bonner, Julia Maeve, Mathys, Hansruedi, Lin, Yuan-Ta, Ko, Tak, Bennett, David A., Cam, Hugh P., Kellis, Manolis, Tsai, Li-Huei

“…A Correction to this paper has been published: https://doi.org/10.1038/s41591-021-01250-8…”
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Functional Analysis of the NHR2 Domain Indicates that Oligomerization of Neuralized Regulates Ubiquitination and Endocytosis of Delta during Notch Signaling by Liu, Sili, Bonner, Julia Maeve, Chanet, Soline, Commisso, Cosimo, Skwarek, Lara C., Schweisguth, François, Boulianne, Gabrielle L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diverse structures, functions and uses of FK506 binding proteins by Bonner, Julia Maeve, Boulianne, Gabrielle L.

“…FK506 (Tacrolimus), isolated from Streptomyces tsukubaenis is a powerful immunosuppressant shown to inhibit T cell activation. FK506 mediated immunosuppression…”
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APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia by Sienski, Grzegorz, Narayan, Priyanka, Bonner, Julia Maeve, Kory, Nora, Boland, Sebastian, Arczewska, Aleksandra A, Ralvenius, William T, Akay, Leyla, Lockshin, Elana, He, Liang, Milo, Blerta, Graziosi, Agnese, Baru, Valeriya, Lewis, Caroline A, Kellis, Manolis, Sabatini, David M, Tsai, Li-Huei, Lindquist, Susan

“…The allele of the apolipoprotein E gene ( ) has been established as a genetic risk factor for many diseases including cardiovascular diseases and Alzheimer's…”
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Nanoparticle‐Mediated Delivery of Anti‐PU.1 siRNA via Localized Intracisternal Administration Reduces Neuroinflammation by Ralvenius, William T., Andresen, Jason L., Huston, Margaret M., Penney, Jay, Bonner, Julia Maeve, Fenton, Owen S., Langer, Robert, Tsai, Li‐Huei

“…Neuroinflammation is a hallmark of neurodegenerative disorders including Alzheimer's disease (AD). Microglia, the brain's immune cells, express many of the…”
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Drosophila as a model to study age-related neurodegenerative disorders: Alzheimer's disease by Bonner, Julia Maeve, Boulianne, Gabrielle L.

“…Alzheimer's Disease (AD) is the most common cause of dementia in the aging population. Although a variety of drug treatments can delay the onset of disease or…”
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FKBP14 in Notch Signalling and Drosophila Development by Bonner, Julia Maeve

“…Presenilins (PSs) are highly conserved transmembrane proteins that form the catalytic core of the gamma-secretase complex, which cleaves a growing list of…”
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