Search Results - "Bonnefoy, Eliette"

Susceptibility to Zika virus in a Collaborative Cross mouse strain is induced by Irf3 deficiency in vitro but requires other variants in vivo by Bourdon, Marie, Manet, Caroline, Conquet, Laurine, Ramaugé Parra, Corentin, Kornobis, Etienne, Bonnefoy, Eliette, Montagutelli, Xavier

“…Zika virus (ZIKV) is a Flavivirus responsible for recent epidemics in Pacific Islands and in the Americas. In humans, the consequences of ZIKV infection range…”
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Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo by Violet, Marie, Chauderlier, Alban, Delattre, Lucie, Tardivel, Meryem, Chouala, Meliza Sendid, Sultan, Audrey, Marciniak, Elodie, Humez, Sandrine, Binder, Lester, Kayed, Rakez, Lefebvre, Bruno, Bonnefoy, Eliette, Buée, Luc, Galas, Marie-Christine

“…Abstract The accumulation of DNA and RNA oxidative damage is observed in cortical and hippocampal neurons from Alzheimer's disease (AD) brains at early stages…”
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Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response by Manet, Caroline, Mansuroglu, Zeyni, Conquet, Laurine, Bortolin, Violaine, Comptdaer, Thomas, Segrt, Helena, Bourdon, Marie, Menidjel, Reyene, Stadler, Nicolas, Tian, Guanfang, Herit, Floriane, Niedergang, Florence, Souès, Sylvie, Buée, Luc, Galas, Marie-Christine, Montagutelli, Xavier, Bonnefoy, Eliette

“…Zika virus (ZIKV) infection at postnatal or adult age can lead to neurological disorders associated with cognitive defects. Yet, how mature neurons respond to…”
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A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells by Le May, Nicolas, Mansuroglu, Zeyni, Léger, Psylvia, Josse, Thibaut, Blot, Guillaume, Billecocq, Agnès, Flick, Ramon, Jacob, Yves, Bonnefoy, Eliette, Bouloy, Michèle

“…Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon beta (IFN-beta) gene expression…”
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Large-Scale Chromatin Immunoprecipitation with Promoter Sequence Microarray Analysis of the Interaction of the NSs Protein of Rift Valley Fever Virus with Regulatory DNA Regions of the Host Genome by BENFERHAT, Rima, JOSSE, Thibaut, ALBAUD, Benoit, GENTIEN, David, MANSUROGLU, Zeyni, MARCATO, Vasco, SOUES, Sylvie, LE BONNIEC, Bernard, BOULOY, Michèle, BONNEFOY, Eliette

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Binding of YY1 to the Proximal Region of the Murine Beta Interferon Promoter Is Essential To Allow CBP Recruitment and K8H4/K14H3 Acetylation on the Promoter Region after Virus Infection by Mokrani, Houda, Sharaf el dein, Ossama, Mansuroglu, Zeyni, Bonnefoy, Eliette

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Inhibition of Histone Deacetylation Induces Constitutive Derepression of the Beta Interferon Promoter and Confers Antiviral Activity by Shestakova, E, Bandu, M T, Doly, J, Bonnefoy, E

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Specific Binding of High-Mobility-Group I (HMGI) Protein and Histone H1 to the Upstream AT-Rich Region of the Murine Beta Interferon Promoter: HMGI Protein Acts as a Potential Antirepressor of the Promoter by Bonnefoy, Eliette, Bandu, Marie-Thérèse, Doly, Janine

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Nuclear Tau, a Key Player in Neuronal DNA Protection by Sultan, Audrey, Nesslany, Fabrice, Violet, Marie, Bégard, Séverine, Loyens, Anne, Talahari, Smail, Mansuroglu, Zeyni, Marzin, Daniel, Sergeant, Nicolas, Humez, Sandrine, Colin, Morvane, Bonnefoy, Eliette, Buée, Luc, Galas, Marie-Christine

“…Tau, a neuronal protein involved in neurodegenerative disorders such as Alzheimer disease, which is primarily described as a microtubule-associated protein,…”
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Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions by Benhelli-Mokrani, Houda, Mansuroglu, Zeyni, Chauderlier, Alban, Albaud, Benoit, Gentien, David, Sommer, Sabrina, Schirmer, Claire, Laqueuvre, Lucie, Josse, Thibaut, Buée, Luc, Lefebvre, Bruno, Galas, Marie-Christine, Souès, Sylvie, Bonnefoy, Eliette

“…Abstract Tauopathies such as Alzheimer's Disease (AD) are neurodegenerative disorders for which there is presently no cure. They are named after the abnormal…”
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Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin by Mansuroglu, Zeyni, Benhelli-Mokrani, Houda, Marcato, Vasco, Sultan, Audrey, Violet, Marie, Chauderlier, Alban, Delattre, Lucie, Loyens, Anne, Talahari, Smail, Bégard, Séverine, Nesslany, Fabrice, Colin, Morvane, Souès, Sylvie, Lefebvre, Bruno, Buée, Luc, Galas, Marie-Christine, Bonnefoy, Eliette

“…Pericentromeric heterochromatin (PCH) gives rise to highly dense chromatin sub-structures rich in the epigenetic mark corresponding to the trimethylated form…”
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The NSs Protein Encoded by the Virulent Strain of Rift Valley Fever Virus Targets the Expression of Abl2 and the Actin Cytoskeleton of the Host, Affecting Cell Mobility, Cell Shape, and Cell-Cell Adhesion by Bamia, Aline, Marcato, Vasco, Boissière, Magali, Mansuroglu, Zeyni, Tamietti, Carole, Romani, Mattea, Simon, Dominique, Tian, Guanfang, Niedergang, Florence, Panthier, Jean-Jacques, Flamand, Marie, Souès, Sylvie, Bonnefoy, Eliette

“…Rift Valley fever virus (RVFV) is a highly pathogenic zoonotic arbovirus endemic in many African countries and the Arabian Peninsula. Animal infections cause…”
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Nuclear Magnetic Resonance Spectroscopy Characterization of Interaction of Tau with DNA and Its Regulation by Phosphorylation by Qi, Haoling, Cantrelle, François-Xavier, Benhelli-Mokrani, Houda, Smet-Nocca, Caroline, Buée, Luc, Lippens, Guy, Bonnefoy, Eliette, Galas, Marie-Christine, Landrieu, Isabelle

“…The capacity of endogenous Tau to bind DNA has been recently identified in neurons under physiological or oxidative stress conditions. Characterization of the…”
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Protein kinase R induced by type I interferons is a main regulator of reactive microglia in Zika virus infection by Bortolin, Violaine, Mansuroglu, Zeyni, Conquet, Laurine, Calcagno, Gaetano, Lambert, Fanny, Marin-Obando, Jose Pablo, Segrt, Helena, Savino, Mary, Menidjel, Reyene, Souès, Sylvie, Buée, Luc, Niedergang, Florence, Galas, Marie-Christine, Montagutelli, Xavier, Bonnefoy, Eliette

“…Microglial cells are the phagocytic cells of the brain that under physiological conditions participate in brain homeostasis and surveillance. Under pathogenic…”
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A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions by Violet, Marie, Delattre, Lucie, Tardivel, Meryem, Sultan, Audrey, Chauderlier, Alban, Caillierez, Raphaelle, Talahari, Smail, Nesslany, Fabrice, Lefebvre, Bruno, Bonnefoy, Eliette, Buée, Luc, Galas, Marie-Christine

“…Nucleic acid protection is a substantial challenge for neurons, which are continuously exposed to oxidative stress in the brain. Neurons require powerful…”
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Tau/DDX6 interaction increases microRNA activity by Chauderlier, Alban, Gilles, Melissa, Spolcova, Andrea, Caillierez, Raphaelle, Chwastyniak, Maggy, Kress, Michel, Drobecq, Herve, Bonnefoy, Eliette, Pinet, Florence, Weil, Dominique, Buée, Luc, Galas, Marie-Christine, Lefebvre, Bruno

“…Tauopathies, such as Alzheimer's disease, are characterized by intracellular aggregates of insoluble Tau proteins. Originally described as a microtubule…”
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β-Catenin Upregulates the Constitutive and Virus-Induced Transcriptional Capacity of the Interferon Beta Promoter through T-Cell Factor Binding Sites by Marcato, Vasco, Luron, Lionel, Laqueuvre, Lucie M., Simon, Dominique, Mansuroglu, Zeyni, Flamand, Marie, Panthier, Jean-Jacques, Souès, Sylvie, Massaad, Charbel, Bonnefoy, Eliette

“…Rapid upregulation of interferon beta (IFN-β) expression following virus infection is essential to set up an efficient innate antiviral response. Biological…”
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Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions by Benhelli-Mokrani, Houda, Mansuroglu, Zeyni, Chauderlier, Alban, Albaud, Benoit, Gentien, David, Sommer, Sabrina, Schirmer, Claire, Laqueuvre, Lucie, Josse, Thibaut, Buée, Luc, Lefebvre, Bruno, Galas, Marie-Christine, Souès, Sylvie, Bonnefoy, Eliette

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Emerging Connections Between Tau and Nucleic Acids by Galas, Marie-Christine, Bonnefoy, Eliette, Buee, Luc, Lefebvre, Bruno

“…Connections between tau and nucleic acids have been largely underestimated until recently when several reports highlighted new key roles of tau in relation…”
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Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization by Sjöberg, Marcela K, Shestakova, Elena, Mansuroglu, Zeyni, Maccioni, Ricardo B, Bonnefoy, Eliette

“…The microtubule-associated tau protein participates in the organization and integrity of the neuronal cytoskeleton. A nuclear form of tau has been described in…”
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