Search Results - "Bonnafous, S"

ER stress induces NLRP3 inflammasome activation and hepatocyte death by Lebeaupin, C, Proics, E, de Bieville, C H D, Rousseau, D, Bonnafous, S, Patouraux, S, Adam, G, Lavallard, V J, Rovere, C, Le Thuc, O, Saint-Paul, M C, Anty, R, Schneck, A S, Iannelli, A, Gugenheim, J, Tran, A, Gual, P, Bailly-Maitre, B

“…The incidence of chronic liver disease is constantly increasing, owing to the obesity epidemic. However, the causes and mechanisms of inflammation-mediated…”
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Posterior auricular artery helix root free flap—part II: clinical application by Pierrefeu, A., Bonnafous, S., Gagnieur, P., Daurade, M.

“…The surgical repair of full-thickness defects involving the alae nasi is complex. Pedicle flaps such as frontal and nasolabial flaps can be used, but require…”
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Screening for therapeutic trials and treatment indication in clinical practice: MACK‐3, a new blood test for the diagnosis of fibrotic NASH by Boursier, J., Anty, R., Vonghia, L., Moal, V., Vanwolleghem, T., Canivet, C. M., Michalak, S., Bonnafous, S., Michielsen, P., Oberti, F., Iannelli, A., Van Gaal, L., Patouraux, S., Blanchet, O., Verrijken, A., Gual, P., Rousselet, M.‐C., Driessen, A., Hunault, G., Bertrais, S., Tran, A., Calès, P., Francque, S.

“…Summary Background The composite histological endpoint comprising nonalcoholic steatohepatitis (NASH) and NAFLD activity score ≥4 and advanced fibrosis (F ≥ 2)…”
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Evolution and safety of day-case major ear surgery by Bonnafous, S., Hermann, R., Zaouche, S., Tringali, S., Fieux, M.

“…To study the evolution of middle-ear surgery in 2019 in relation to the French Health Authority target of 66% day-surgery by 2020. A single-center…”
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A new composite model including metabolic syndrome, alanine aminotransferase and cytokeratin‐18 for the diagnosis of non‐alcoholic steatohepatitis in morbidly obese patients by Anty, R., Iannelli, A., Patouraux, S., Bonnafous, S., Lavallard, V. J., Senni‐Buratti, M., Ben Amor, I., Staccini‐Myx, A., Saint‐Paul, M.‐C., Berthier, F., Huet, P.‐M., Le Marchand‐Brustel, Y., Gugenheim, J., Gual, P., Tran, A.

“…Aliment Pharmacol Ther 2010; 32: 1315–1322 Summary Background  Non‐invasive approaches are useful to differentiate simple steatosis from non‐alcoholic…”
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Matrix Metalloproteinases Are Differentially Expressed in Adipose Tissue during Obesity and Modulate Adipocyte Differentiation by Chavey, Carine, Mari, Bernard, Monthouel, Marie-Noëlle, Bonnafous, Stéphanie, Anglard, Patrick, Van Obberghen, Emmanuel, Tartare-Deckert, Sophie

“…Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix remodeling, a process that takes place during obesity-mediated adipose tissue…”
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Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice by Patouraux, S, Rousseau, D, Rubio, A, Bonnafous, S, Lavallard, V J, Lauron, J, Saint-Paul, M-C, Bailly-Maitre, B, Tran, A, Crenesse, D, Gual, P

“…Osteopontin (OPN) is a multifunctional protein involved in hepatic steatosis, inflammation, fibrosis and cancer progression. However, its role in hepatic…”
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Involvement of TNF-α in abnormal adipocyte and muscle sortilin expression in obese mice and humans by Kaddai, V, Jager, J, Gonzalez, T, Najem-Lendom, R, Bonnafous, S, Tran, A, Le Marchand-Brustel, Y, Gual, P, Tanti, J.-F, Cormont, M

“…Aims/hypothesis Insulin resistance is caused by numerous factors including inflammation. It is characterised by defective insulin stimulation of adipocyte and…”
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Tudca Protects against Endoplasmic Reticulum Stress-Induced Inflammasome Activation and Hepatocyte Death in Non-Alcoholic Steatohepatitis by Lebeaupin, C, Proics, E, de Bieville, C.-H.D, Rousseau, D, Bonnafous, S, Patouraux, S, Tran, A, Gual, P, Bailly-Maitre, B

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P0941 : CD44 is an important actor in non alcoholic steatohepatitis by Rousseau, D, Anty, R, Bonnafous, S, Patouraux, S, Schneck, A.-S, Iannelli, A, Saint-Paul, M.-C, Gugenheim, J, Bailly-Maitre, B, Tran, A, Gual, P

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P3 INVALIDATION OF OSTEOPONTIN AGGRAVATES HEPATIC INJURY INDUCED BY ISCHEMIA–REPERFUSION IN MICE by Patouraux, S, Rousseau, D, Rubio, A, Lauron, J, Bonnafous, S, Lavallard, V.J, Saint-Paul, M.-C, Bailly-Maitre, B, Tran, A, Crenesse, D, Gual, P

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1274 MORBIDLY OBESE PATIENTS WITH ALANINE AMINOTRANSFERASE (ALT) LEVEL BELOW THE THRESHOLD 0.5 TIMES THE UPPER LIMIT OF NORMAL HAVE NO NASH by Anty, R, Iannelli, A, Patouraux, S, Bonnafous, S, Lavallard, V, Marine-Barjoan, E, Schneck, A.-S, Paul, M.C. Saint, Huet, P.M, Marchand-Brustel, Y. Le, Gugenheim, J, Gual, P, Tran, A

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1349 ELEVATED OSTEOPONTIN EXPRESSION IN LIVER, ADIPOSE TISSUE AND SERUM IS CORRELATED WITH FIBROSIS IN PATIENTS WITH ALCOHOLIC LIVER DISEASE by Patouraux, S, Bonnafous, S, Voican, C.S, Anty, R, Saint-Paul, M.-C, Rosenthal-Allieri, M.-A, Agostini, H, Njike, M, Barri-Ova, N, Naveau, S, Marchand-Brustel, Y. Le, Cales, P, Perlemuter, G, Tran, A, Gual, P

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93 C-REACTIVE PROTEIN INHIBITS INSULIN SIGNALLING PATHWAY IN BOTH HUMAN HEPATOCYTES AND ADIPOCYTES by Bertola, A, Anty, R, Bonnafous, S, Le Marchand-Brustel, Y, Tran, A, Gual, P

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789 ROLE OF THE AUTOPHAGY IN HEPATOCYTE DEATH IN NONALCOHOLIC FATTY LIVER DISEASE (NAFLD): STUDY IN VITRO, IN MICE AND IN HUMANS by Lavallard, V, Bonnafous, S, Rousseau, D, Bailly-Maitre, B, Anty, R, Saint-Paul, M.-C, Sadoul, J.-L, Ianelli, A, Deveaux, V, Lotersztajn, S, Gounon, P, Gugenheim, J, Le Marchand-Brustel, Y, Tran, A, Gual, P

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696 ELEVATED EXPRESSION OF OSTEOPONTIN IS RELATED TO ADIPOSE TISSUE MACROPHAGE ACCUMULATION AND LIVER STEATOSIS IN MORBID OBESITY by Bertola, A, Deveaux, V, Bonnafous, S, Rousseau, D, Anty, R, Wakkach, A, Dahman, M, Tordjman, J, Clément, K, McQuaid, S.E, Frayn, K.N, Huet, P.M, Gugenheim, J, Lotersztajn, S, Le Marchand-Brustel, Y, Tran, A, Gual, P

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The formation of an intrachain disulfide bond in the leptin protein is necessary for efficient leptin secretion by Boute, N., Zilberfarb, V., Camoin, L., Bonnafous, S., Le Marchand-Brustel, Y., Issad, T.

“…Leptin is a cytokine secreted by the adipose tissue that is involved in the control of body weight. We previously showed that a point mutation (R105W) in…”
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PO24 Le stress du réticulum endoplasmique dialogue avec l’inflammasome dans la pathophysiologie des stéatophaties métaboliques by Bailly-Maitre, B, Desnoyer de Bieville, C.-H, Proics, E, Patouraux, S, Rousseau, D, Bonnafous, S, Saint-Paul, M.-C, Le Marchand-Brustel, Y, Gual, P, Tran, A

“…Introduction Les complications hépatiques associées à l’obésité vont de la stéatose simple, dont le pronostic est excellent, à la stéatohépatite (NASH), plus…”
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O58 Implication des protéines des gouttelettes lipidiques dans la résistance a l’insuline hépatique by Bouduban, T, Gual, P, Tran, A, Bonnafous, S, Postic, C, Minehira, K

“…Introduction La prévalence des maladies stéatosiques non alcooliques du foie augmente de manière exponentielle dans les pays industrialisés. Le développement…”
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076 Accumulation de cellules dendritiques dans le tissu adipeux en fonction de l’obésité et de l’insulino-résistance chez la souris et les patients by Ciucci, T, Bertola, A, Rousseau, D, Bourlier, V, Duffaut, C, Bonnafous, S, Blin-Wakkach, C, Anty, R, Iannelli, A, Gugenheim, J, Tran, A, Bouloumié, A, Wakkach, A, Gual, P

“…Introduction La régulation des cellules T dans le tissu adipeux constitue un lien important entre l’inflammation et l’insulino-résistance. Nous avons recherché…”
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