Search Results - "Bonito, Paola"

Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation by Di Bonito, Paola, Chiozzini, Chiara, Arenaccio, Claudia, Anticoli, Simona, Manfredi, Francesco, Olivetta, Eleonora, Ferrantelli, Flavia, Falcone, Emiliana, Ruggieri, Anna, Federico, Maurizio

“…We recently proved that exosomes engineered in vitro to deliver high amounts of HPV E7 upon fusion with the Nef exosome-anchoring protein elicit an efficient…”
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Incorporation of Heterologous Proteins in Engineered Exosomes by Manfredi, Francesco, Di Bonito, Paola, Arenaccio, Claudia, Anticoli, Simona, Federico, Maurizio

“…Engineering exosomes to upload heterologous proteins represents the last frontier in terms of nanoparticle-based technology. A limited number of methods…”
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HPV-E7 delivered by engineered exosomes elicits a protective CD8⁺ T cell-mediated immune response by Di Bonito, Paola, Ridolfi, Barbara, Columba-Cabezas, Sandra, Giovannelli, Andrea, Chiozzini, Chiara, Manfredi, Francesco, Anticoli, Simona, Arenaccio, Claudia, Federico, Maurizio

“…We developed an innovative strategy to induce a cytotoxic T cell (CTL) immune response against protein antigens of choice. It relies on the production of…”
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Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity by Flego, Michela, Frau, Aldo, Accardi, Luisa, Mallano, Alessandra, Ascione, Alessandro, Gellini, Mara, Fanunza, Elisa, Vella, Stefano, Di Bonito, Paola, Tramontano, Enzo

“…Ebola hemorrhagic fever is caused by the Ebola filovirus (EBOV), which is one of the most aggressive infectious agents known worldwide. The EBOV pathogenesis…”
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In vivo antitumor effect of an intracellular single‐chain antibody fragment against the E7 oncoprotein of human papillomavirus 16 by Accardi, Luisa, Paolini, Francesca, Mandarino, Angela, Percario, Zulema, Bonito, Paola, Carlo, Valentina, Affabris, Elisabetta, Giorgi, Colomba, Amici, Carla, Venuti, Aldo

“…Human papillomavirus (HPV)‐associated tumors still represent an urgent problem of public health in spite of the efficacy of the prophylactic HPV vaccines…”
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Human Oncogenic Viruses: Characteristics and Prevention Strategies-Lessons Learned from Human Papillomaviruses by Galati, Luisa, Chiantore, Maria Vincenza, Marinaro, Mariarosaria, Di Bonito, Paola

“…Approximately 12% of human cancers worldwide are associated with infectious agents, which are classified by the International Agency for Research on Cancer…”
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Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy by Illiano, Elena, Demurtas, Olivia Costantina, Massa, Silvia, Di Bonito, Paola, Consalvi, Valerio, Chiaraluce, Roberta, Zanotto, Carlo, De Giuli Morghen, Carlo, Radaelli, Antonia, Venuti, Aldo, Franconi, Rosella

“…High-risk human papillomaviruses (HR-HPVs) types 16 and 18 are the main etiological agents of cervical cancer, with more than 550,000 new cases each year…”
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Anti-Cancer Vaccine for HPV-Associated Neoplasms: Focus on a Therapeutic HPV Vaccine Based on a Novel Tumor Antigen Delivery Method Using Endogenously Engineered Exosomes by Di Bonito, Paola, Accardi, Luisa, Galati, Luisa, Ferrantelli, Flavia, Federico, Maurizio

“…Some human papillomavirus (HPV) genotypes are universally recognized as major etiological agents not only of ano-genital tumors but also of head and neck…”
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Identification of novel linear megaplasmids carrying a ß-lactamase gene in neurotoxigenic Clostridium butyricum type E strains by Franciosa, Giovanna, Scalfaro, Concetta, Di Bonito, Paola, Vitale, Marco, Aureli, Paolo

“…Since the first isolation of type E botulinum toxin-producing Clostridium butyricum from two infant botulism cases in Italy in 1984, this peculiar…”
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HPV16 Phylogenetic Variants in Anogenital and Head and Neck Cancers: State of the Art and Perspectives by Galati, Luisa, Di Bonito, Paola, Marinaro, Mariarosaria, Chiantore, Maria Vincenza, Gheit, Tarik

“…HPV16 is responsible for approximately 60% and 90% of global HPV-induced cervical and oropharyngeal cancers, respectively. HPV16 intratype variants have been…”
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Seroprevalence of Toscana virus in blood donors, France, 2007 by Brisbarre, Nadège, Attoui, Houssam, Gallian, Pierre, Di Bonito, Paola, Giorgi, Colomba, Cantaloube, Jean-Francois, Biagini, Philippe, Touinssi, Mhammed, Jordier, Francois, de Micco, Philippe

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Remission of HPV-Related Diseases by Antivirals for Herpesvirus: Clinical Cases and a Literature Review by Balestrieri, Maria, Chiantore, Maria Vincenza, Garbuglia, Anna Rosa, Carnovale-Scalzo, Caterina, Falcucci, Susanna, Di Bonito, Paola

“…Epidemiological studies have shown that HPV-related diseases are the most prevalent sexually transmitted infections. In this context, this report will present…”
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Targeting Human Papillomavirus-Associated Cancer by Oncoprotein-Specific Recombinant Antibodies by Donà, Maria Gabriella, Di Bonito, Paola, Chiantore, Maria Vincenza, Amici, Carla, Accardi, Luisa

“…In recent decades, recombinant antibodies against specific antigens have shown great promise for the therapy of infectious diseases and cancer. Human…”
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Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors by Paolini, Francesca, Amici, Carla, Carosi, Mariantonia, Bonomo, Claudia, Di Bonito, Paola, Venuti, Aldo, Accardi, Luisa

“…The oncogenic activity of the high risk human papillomavirus type 16 (HPV16) is fully dependent on the E6 and E7 viral oncoproteins produced during viral…”
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Epitope Mapping and Computational Analysis of Anti-HPV16 E6 and E7 Antibodies in Single-Chain Format for Clinical Development as Antitumor Drugs by Amici, Carla, Donà, Maria Gabriella, Chirullo, Barbara, Di Bonito, Paola, Accardi, Luisa

“…Human Papillomavirus 16-associated cancer, affecting primarily the uterine cervix but, increasingly, other body districts, including the head–neck area, will…”
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Plant Molecular Farming as a Strategy Against COVID-19 - The Italian Perspective by Lico, Chiara, Santi, Luca, Baschieri, Selene, Noris, Emanuela, Marusic, Carla, Donini, Marcello, Pedrazzini, Emanuela, Maga, Giovanni, Franconi, Rosella, Di Bonito, Paola, Avesani, Linda

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed more than 37,000 people in Italy and has caused widespread socioeconomic disruption…”
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Conventional therapy for genital herpesvirus and remission of HPV-related lesions: a case series by Balestrieri, Maria, Carnovale-Scalzo, Caterina, Garbuglia, Anna Rosa, Chiantore, Maria Vincenza, Accardi, Luisa, Di Bonito, Paola

“…This report covers the case of 7 women affected by pathologies related to genital Herpesvirus and Papillomavirus. They were referred to the gynaecology…”
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Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model by Petrone, Linda, Ammendolia, Maria G, Cesolini, Armando, Caimi, Stefano, Superti, Fabiana, Giorgi, Colomba, Di Bonito, Paola

“…The HPV16 E7 protein is both a tumour-specific and a tumour-rejection antigen, the ideal target for developing therapeutic vaccines for the treatment of…”
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Antibodies Induced by Smallpox Vaccination after at Least 45 Years Cross-React with and In Vitro Neutralize Mpox Virus: A Role for Polyclonal B Cell Activation? by Mariotti, Sabrina, Venturi, Giulietta, Chiantore, Maria Vincenza, Teloni, Raffaela, De Santis, Riccardo, Amendola, Antonello, Fortuna, Claudia, Marsili, Giulia, Grilli, Giorgia, Lia, Maria Stella, Kiros, Seble Tekle, Lagi, Filippo, Bartoloni, Alessandro, Iacobino, Angelo, Cresta, Raffaele, Lastilla, Marco, Biselli, Roberto, Di Bonito, Paola, Lista, Florigio, Nisini, Roberto

“…To evaluate whether antibodies specific for the vaccinia virus (VV) are still detectable after at least 45 years from immunization. To confirm that VV-specific…”
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Virus-Induced Tumorigenesis and IFN System by Iuliano, Marco, Mangino, Giorgio, Chiantore, Maria Vincenza, Di Bonito, Paola, Rosa, Paolo, Affabris, Elisabetta, Romeo, Giovanna

“…Oncogenic viruses favor the development of tumors in mammals by persistent infection and specific cellular pathways modifications by deregulating cell…”
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