Search Results - "Bonin, Irena"

Active Site Geometry and Substrate Recognition of the Molybdenum Hydroxylase Quinoline 2-Oxidoreductase by Bonin, Irena, Martins, Berta M., Purvanov, Vladimir, Fetzner, Susanne, Huber, Robert, Dobbek, Holger

“…The soil bacterium Pseudomonas putida 86 uses quinoline as a sole source of carbon and energy. Quinoline 2-oxidoreductase (Qor) catalyzes the first metabolic…”
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Structural Basis for the Interaction of Escherichia coli NusA with Protein N of Phage λ by Bonin, Irena, Mühlberger, Rene, Bourenkov, Gleb P., Huber, Robert, Bacher, Adelbert, Richter, Gerald, Wahl, Markus C.

“…The C terminus of transcription factor NusA from Escherichia coli comprises two repeat units, which bind during antitermination to protein N from phage λ. To…”
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Design and Synthesis of Novel [60]Fullerene Derivatives as Potential HIV Aspartic Protease Inhibitors by Marcorin, Gian Luca, Da Ros, Tatiana, Castellano, Sabrina, Stefancich, Giorgio, Bonin, Irena, Miertus, Stanislav, Prato, Maurizio

“…Two water-soluble fullerene derivatives have been computer-designed and synthesized. They may exhibit interesting anti-HIV activity owing to the presence of…”
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Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding by Bonin, Irena, Robelek, Rudolf, Benecke, Heike, Urlaub, Henning, Bacher, Adelbert, Richter, Gerald, Wahl, Markus C

“…NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site…”
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Computational Design of New Cyclic Urea Inhibitors for Improved Binding of HIV-1 Aspartic Protease by Kotamarthi, Bhanuprakash, Bonin, Irena, Benedetti, Fabio, Miertus, Stanislav

“…We report in this paper the design, by means of computational techniques, of new cyclic urea inhibitors of the HIV aspartic protease. The relationship between…”
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Computational studies of the resistance patterns of mutant HIV-1 aspartic proteases towards ABT-538 (ritonavir) and design of new derivatives by Nair, Anil C, Bonin, Irena, Tossi, Alessandro, Welsh, William J, Miertus, Stanislav

“…Kinetic characterization and cross resistance pattern studies of HIV-1 aspartic protease (PR) inhibitors have shown that some mutations cause considerable…”
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Aspartic protease inhibitors: An integrated approach for the design and synthesis of diaminodiol‐based peptidomimetics by Tossi, Alessandro, Bonin, Irena, Antcheva, Nikolinka, Norbedo, Stefano, Benedetti, Fabio, Miertus, Stanislav, Nair, Anil C., Maliar, Tibor, Dal Bello, Federico, Palù, Giorgio, Romeo, Domenico

“…Aspartic proteases play key roles in a variety of pathologies, including acquired immunodeficiency syndrome. Peptidomimetic inhibitors can act as drugs to…”
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Aspartic protease inhibitors by Tossi, Alessandro, Bonin, Irena, Antcheva, Nikolinka, Norbedo, Stefano, Benedetti, Fabio, Miertus, Stanislav, Nair, Anil C., Maliar, Tibor, Dal Bello, Federico, Palù, Giorgio, Romeo, Domenico

“…Aspartic proteases play key roles in a variety of pathologies, including acquired immunodeficiency syndrome. Peptidomimetic inhibitors can act as drugs to…”
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