Search Results - "Bongarzone, E.R."

Deregulation of signalling in genetic conditions affecting the lysosomal metabolism of cholesterol and galactosyl-sphingolipids by Gowrishankar, S., Cologna, S.M., Givogri, M.I., Bongarzone, E.R.

“…The role of lipids in neuroglial function is gaining momentum in part due to a better understanding of how many lipid species contribute to key cellular…”
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Cerebellar neurons and glial cells are transducible by lentiviral vectors without decrease of cerebellar functions by Croci, C, Fasano, S, Superchi, D, Perani, L, Martellosio, A, Brambilla, R, Consalez, G, Bongarzone, E R

“…Due to the profuse connections of the cerebellum to the rest of the central nervous system, cerebellar dysfunction impacts tremendously on movement…”
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Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease by White, A.B., Galbiati, F., Givogri, M.I., Lopez Rosas, A., Qiu, X., van Breemen, R., Bongarzone, E.R.

“…Sphingolipids are intrinsic components of membrane lipid rafts. The abnormal accumulation of these molecules may introduce architectural and functional changes…”
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Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease by Galbiati, F., Givogri, M.I., Cantuti, L., Lopez Rosas, A., Cao, H., van Breemen, R., Bongarzone, E.R.

“…This study characterized the therapeutic benefits of combining hematogenous cell replacement with lentiviral‐mediated gene transfer of galactosylceramidase…”
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Two neuronal cell lines expressing the myelin basic protein gene display differences in their in vitro survival and in their response to glia by Bongarzone, E.R., Foster, L., Byravan, S., Casaccia-Bonnefil, P., Schonmann, V., Campagnoni, A.T.

“…We have generated two conditionally immortalized neuronal cell lines from primary cultures of embryonic day 13 (E13) and postmitotic (postnatal day 0; P0)…”
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Conditionally Immortalized Neural Cell Lines: Potential Models for the Study of Neural Cell Function by Bongarzone, E.R., Foster, L.M., Byravan, S., Verity, A.N., Landry, C.F., Schonmann, V., Amur-Umarjee, S., Campagnoni, A.T.

“…Studies on primary cell cultures have contributed significantly to our understanding of neural cell function. Nevertheless, for many studies the value of these…”
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Single intracerebral injection of apotransferrin in young rats induces increased myelination by Escobar Cabrera, O E, Bongarzone, E R, Soto, E F, Pasquini, J M

“…Three-day-old rats were injected intracranially with 210 or 350 ng of apotransferrin (aTf) to study the possible neurotrophic effects of this iron transport…”
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