Search Results - "Bonfanti, Gianluca"

Machine learning prediction and explanatory models of serious infections in patients with rheumatoid arthritis treated with tofacitinib by Hetland, Merete Lund, Strangfeld, Anja, Bonfanti, Gianluca, Soudis, Dimitrios, Deuring, J Jasper, Edwards, Roger A

“…Patients with rheumatoid arthritis (RA) have an increased risk of developing serious infections (SIs) vs. individuals without RA; efforts to predict SIs in…”
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Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies by Lees, Charlie W., Deuring, J. Jasper, Chiorean, Michael, Daperno, Marco, Bonfanti, Gianluca, Germino, Rebecca, Brown, Pritha Bhadra, Modesto, Irene, Edwards, Roger A.

“…Introduction: Tofacitinib is an oral, small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Outcome prediction based on early…”
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Using time series analysis approaches for improved prediction of pain outcomes in subgroups of patients with painful diabetic peripheral neuropathy by Alexander, Jr, Joe, Edwards, Roger A, Brodsky, Marina, Manca, Luigi, Grugni, Roberto, Savoldelli, Alberto, Bonfanti, Gianluca, Emir, Birol, Whalen, Ed, Watt, Steve, Parsons, Bruce

“…Prior work applied hierarchical clustering, coarsened exact matching (CEM), time series regressions with lagged variables as inputs, and microsimulation to…”
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Impact of Previous Alopecia Areata Treatment on Efficacy Responses up to Week 48 Following Ritlecitinib Treatment: A Post Hoc Analysis by Fu, Jennifer, Egeberg, Alexander, Holmes, Susan, Vano-Galvan, Sergio, Steinhoff, Martin, Edwards, Roger, Bonfanti, Gianluca, Nagra, Ranjit, Wolk, Robert, Tran, Helen, Law, Ernest

“…Introduction Patients with alopecia areata (AA) may have received several therapies for management of AA during their lives. In the ALLEGRO phase 2b/3…”
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Hair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the ALLEGRO Phase 2b/3 Study by Thaçi, Diamant, Tziotzios, Christos, Ito, Taisuke, Ko, Justin, Karadağ, Ayşe Serap, Fang, Hong, Edwards, Roger A., Bonfanti, Gianluca, Wolk, Robert, Tran, Helen, Law, Ernest

“…Introduction Ritlecitinib demonstrated efficacy in patients with alopecia areata (AA) in the ALLEGRO phase 2b/3 study (NCT03732807). However, hair loss…”
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Correction: Using time series analysis approaches for improved prediction of pain outcomes in subgroups of patients with painful diabetic peripheral neuropathy by Alexander, Jr, Joe, Edwards, Roger A, Brodsky, Marina, Manca, Luigi, Grugni, Roberto, Savoldelli, Alberto, Bonfanti, Gianluca, Emir, Birol, Whalen, Ed, Watt, Steve, Parsons, Bruce

“…[This corrects the article DOI: 10.1371/journal.pone.0207120.]…”
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52741 Efficacy of Abrocitinib Versus Dupilumab on Dermatitis in the Head-and-Neck Region of Patients With Moderate-To-Severe Atopic Dermatitis: A Post Hoc Analysis of the Phase 3 JADE DARE Study by Armstrong, April W., Gooderham, Melinda J., Eyerich, Kilian, Reich, Kristian, Blauvelt, Andrew, Hong, H. Chih-ho, Edwards, Roger A., Bonfanti, Gianluca, Chan, Gary, Güler, Erman, Feeney, Claire

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A Two-Step, Trajectory-Focused, Analytics Approach to Attempt Prediction of Analgesic Response in Patients with Moderate-to-Severe Osteoarthritis by Atkinson, Joanna, Edwards, Roger A., Bonfanti, Gianluca, Barroso, Joana, Schnitzer, Thomas J.

“…Introduction We sought to predict analgesic response to daily oral nonsteroidal anti-inflammatory drugs (NSAIDs) or subcutaneous tanezumab 2.5 mg (every…”
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Characterizing 16-Week Responder Profiles Using Group-Based Trajectory Modeling in Over 4300 Clinical Trial Participants Receiving Pharmaceutical Treatment for Moderate to Severe Osteoarthritis by Schnitzer, Thomas J., Bonfanti, Gianluca, Atkinson, Joanna, Donevan, Sean, Viktrup, Lars, Barroso, Joana, Whalen, Edward, Edwards, Roger A.

“…Introduction We sought to identify and characterize distinct responder profiles among osteoarthritis (OA) subjects treated with tanezumab, nonsteroidal…”
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Modeling of Treatment Outcomes with Tofacitinib Maintenance Therapy in Patients with Ulcerative Colitis: A Post Hoc Analysis of Data from the OCTAVE Clinical Program by Chiorean, Michael, Daperno, Marco, Lees, Charlie W., Bonfanti, Gianluca, Soudis, Dimitrios, Modesto, Irene, Deuring, J. Jasper, Edwards, Roger A.

“…Introduction Tofacitinib is an oral small molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). This post hoc analysis assessed whether…”
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Predicting Responses to Pregabalin for Painful Diabetic Peripheral Neuropathy Based on Trajectory-Focused Patient Profiles Derived from the First 4 Weeks of Treatment by Edwards, Roger A., Bonfanti, Gianluca, Grugni, Roberto, Manca, Luigi, Parsons, Bruce, Alexander, Joe

“…Introduction Prediction of final clinical outcomes based on early weeks of treatment can enable more effective patient care for chronic pain. Our goal was to…”
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Dose Titration of Pregabalin in Patients with Painful Diabetic Peripheral Neuropathy: Simulation Based on Observational Study Patients Enriched with Data from Randomized Studies by Alexander, Joe, Edwards, Roger A., Manca, Luigi, Grugni, Roberto, Bonfanti, Gianluca, Emir, Birol, Whalen, Edward, Watt, Stephen, Parsons, Bruce

“…Introduction Achieving a therapeutic response to pregabalin in patients with painful diabetic peripheral neuropathy (pDPN) requires adequate upward dose…”
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Integrating Machine Learning With Microsimulation to Classify Hypothetical, Novel Patients for Predicting Pregabalin Treatment Response Based on Observational and Randomized Data in Patients With Painful Diabetic Peripheral Neuropathy by Alexander, Jr, Joe, Edwards, Roger A, Manca, Luigi, Grugni, Roberto, Bonfanti, Gianluca, Emir, Birol, Whalen, Ed, Watt, Steve, Brodsky, Marina, Parsons, Bruce

“…Variability in patient treatment responses can be a barrier to effective care. Utilization of available patient databases may improve the prediction of…”
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