Search Results - "Bone, ND"

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia by Lee, Yean K., Bone, Nancy D., Strege, Ann K., Shanafelt, Tait D., Jelinek, Diane F., Kay, Neil E.

“…We recently reported that chronic lymphocytic leukemia (CLL) cells synthesize and release vascular endothelial growth factor (VEGF) under normoxic and hypoxic…”
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VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance by LEE, Y. K, SHANAFELT, T. D, BONE, N. D, STREGE, A. K, JELINEK, D. F, KAY, N. E

“…We have previously shown that chronic lymphocytic leukemia (CLL) B cells secrete vascular endothelial growth factor (VEGF) in vitro, have constitutively active…”
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Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B‐cell chronic lymphocytic leukaemia by Dewald, Gordon W., Brockman, Stephanie R., Paternoster, Sarah F., Bone, Nancy D., O'Fallon, Judith R., Allmer, Cristine, James, Charles D., Jelinek, Diane F., Tschumper, Renee C., Hanson, Curtis A., Pruthi, Rajiv K., Witzig, Thomas E., Call, Timothy G., Kay, Neil E.

“…Fluorescence in situ hybridization (FISH) was used to detect 6q–, 11q–, +12, 13q–, 17p– and translocations involving 14q32 in interphase nuclei from blood…”
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Analysis of clonal B‐cell CD38 and immunoglobulin variable region sequence status in relation to clinical outcome for B‐chronic lymphocytic leukaemia by Jelinek, Diane F., Tschumper, Renee C., Geyer, Susan M., Bone, Nancy D., Dewald, Gordon W., Hanson, Curtis A., Stenson, Mary J., Witzig, Thomas E., Tefferi, Ayalew, Kay, Neil E.

“…Recent reports suggest that the expression of germline (GL) Ig variable region heavy‐chain genes (VH) is a negative prognostic factor for B‐cell chronic…”
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Expression of the chemokine receptors CXCR4 and CCR7 and disease progression in B-cell chronic lymphocytic leukemia/ small lymphocytic lymphoma by Ghobrial, Irene M, Bone, Nancy D, Stenson, Mary J, Novak, Anne, Hedin, Karen E, Kay, Neil E, Ansell, Stephen M

“…To assess the clinical relevance of chemokine receptor expression on the progression of B-cell chronic lymphocytic leukemia (B-CLL). Peripheral blood…”
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B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules by KAY, N. E, BONE, N. D, TSCHUMPER, R. C, HOWELL, K. H, GEYER, S. M, DEWALD, G. W, HANSON, C. A, JELINEK, D. F

“…Initial work has shown that clonal B cells from B-chronic lymphocytic leukemia (B-CLL) are able to synthesize pro-angiogenic molecules. In this study, our goal…”
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Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine by Shanafelt, Tait D., Lee, Yean K., Bone, Nancy D., Strege, Ann K., Narayanan, Ven L., Sausville, Edward A., Geyer, Susan M., Kaufmann, Scott H., Kay, Neil E.

“…B-cell chronic lymphocytic leukemia (CLL) is characterized by accumulation of clonal lymphocytes resistant to apoptosis. We evaluated the ability of the…”
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A recombinant IL-4- Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells by Kay, Neil E., Bone, Nancy D., Lee, Yean K., Jelinek, Diane F., Leland, Pamela, Battle, Traci E., Frank, David A., Puri, Raj K.

“…We have determined that CLL B cells consistently express type 3 membrane receptors for the Th2-derived cytokine IL-4 (IL-4R). Furthermore, when added to CLL B…”
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Human T-cell function in experimental ascorbic acid deficiency and spontaneous scurvy by Kay, NE, Holloway, DE, Hutton, SW, Bone, ND, Duane, WC

“…Studies in animal models suggest that ascorbic acid deficiency impairs T-cell-mediated immunity. We studied five normal volunteers hospitalized on a metabolic…”
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